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A mathematical model for two solutes transport in a poroelastic material and its applications. (English) Zbl 1537.35343

Summary: Using well-known mathematical foundations of the elasticity theory, a mathematical model for two solutes transport in a poroelastic material (soft tissue is a typical example) is suggested. It is assumed that molecules of essentially different sizes dissolved in fluid and are transported through pores of different sizes. The stress tensor, the main force leading to the material deformation, is taken not only in the standard linear form but also with an additional nonlinear part. The model is constructed in 1D space and consists of five nonlinear equations. It is shown that the governing equations are integrable in stationary case, therefore all steady-state solutions are constructed. The obtained solutions are used in an example for healthy and tumour tissue, in particular, tissue displacements are calculated and compared for parameters taken from experimental data in cases of the linear and nonlinear stress tensors. Since the governing equations are non-integrable in non-stationary case, the Lie symmetry analysis is used in order to construct time-dependent exact solutions. Depending on parameters arising in the governing equations, several special cases with non-trivial Lie symmetries are identified. As a result, multiparameter families of exact solutions are constructed including those in terms of special functions(hypergeometric and Bessel functions). A possible application of the solutions obtained is demonstrated.

MSC:

35Q92 PDEs in connection with biology, chemistry and other natural sciences
35Q35 PDEs in connection with fluid mechanics
76T20 Suspensions
76S05 Flows in porous media; filtration; seepage
74F10 Fluid-solid interactions (including aero- and hydro-elasticity, porosity, etc.)
74L15 Biomechanical solid mechanics
74B20 Nonlinear elasticity
92C17 Cell movement (chemotaxis, etc.)
92C37 Cell biology
92C50 Medical applications (general)
35C05 Solutions to PDEs in closed form
33C20 Generalized hypergeometric series, \({}_pF_q\)
33C10 Bessel and Airy functions, cylinder functions, \({}_0F_1\)
37K10 Completely integrable infinite-dimensional Hamiltonian and Lagrangian systems, integration methods, integrability tests, integrable hierarchies (KdV, KP, Toda, etc.)
17B80 Applications of Lie algebras and superalgebras to integrable systems

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