Summary: The stress-driven nonlocal integral model of elasticity for 1D nano-structures [G. Romano and R. Barretta, Int. J. Eng. Sci. 115, 14–27 (2017; Zbl 1423.74512)] is extended in this paper to Kirchhoff axisymmetric nano-plates. The nonlocal formulation, relating elastic principal flexural curvatures and moments, provides an effective methodology to assess size effects in 2D nano-structures. The associated elastostatic problem of nano-plates is conveniently expressed by differential relations equipped with constitutive boundary conditions involving nonlocal curvature fields. The proposed approach is illustrated by examining case-studies of engineering interest. In particular, nonlocal displacement solutions of axisymmetric nano-plates are detected for a variety of loading systems and kinematic boundary conditions. Merits and implications of the stress-driven strategy are elucidated by comparing the achieved results with those of the strain gradient model of elasticity generated by Reissner’s variational principle. The outcomes can be useful for design and optimization of plate-like components of ground-breaking Nano-Electro-Mechanical-Systems (NEMS).