Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD (Q58433147)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json

post-traumatic stress disorder

31 March 2020

main subject

molecular medicine

0 references

1 reference

1 reference

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Marangelie Criado-Marrero

31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

1 reference

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31 March 2020

Jonathan J Sabbagh

1 reference

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31 March 2020

Ricardo A Cordova

1 reference

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31 March 2020

Andrea Lemus

1 reference

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31 March 2020

Pengfei Li

1 reference

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31 March 2020

Jeremy D Baker

1 reference

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31 March 2020

Bryce A Nordhues

1 reference

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31 March 2020

April L Darling

1 reference

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31 March 2020

Carlos Martinez-Licha

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Daniel A Rutz

1 reference

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31 March 2020

Shreya Patel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Johannes Buchner

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Chad A Dickey

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

language of work or name

English

0 references

publication date

19 June 2018

1 reference

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31 March 2020

1 reference

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31 March 2020

volume

1 reference

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31 March 2020

issue

1 reference

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31 March 2020

page(s)

2288-2299

1 reference

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describes a project that uses

31 March 2020

ImageQuant

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11 June 2022

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inferred from PubMed Central ID database lookup

ImageJ

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11 June 2022

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30 November 2018

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30 November 2018

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30 November 2018

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30 November 2018

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The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules.

30 November 2018

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30 November 2018

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The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders

30 November 2018

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Gene expression patterns associated with posttraumatic stress disorder following exposure to the World Trade Center attacks

30 November 2018

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Aging analysis reveals slowed tau turnover and enhanced stress response in a mouse model of tauopathy

30 November 2018

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30 November 2018

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Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults

30 November 2018

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30 November 2018

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30 November 2018

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Identification of small-molecule inhibitors of RGS4 using a high-throughput flow cytometry protein interaction assay

30 November 2018

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30 November 2018

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Postreactivation glucocorticoids impair recall of established fear memory.

30 November 2018

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Glucocorticoid resistance in squirrel monkeys results from a combination of a transcriptionally incompetent glucocorticoid receptor and overexpression of the glucocorticoid receptor co-chaperone FKBP51.

30 November 2018

1 reference

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Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression.

30 November 2018

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Cochaperone immunophilin FKBP52 is critical to uterine receptivity for embryo implantation

30 November 2018

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Psychosis and the genetic spectrum of bipolar disorder: evidence from linkage analysis.

30 November 2018

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Differential control of glucocorticoid receptor hormone-binding function by tetratricopeptide repeat (TPR) proteins and the immunosuppressive ligand FK506.

30 November 2018

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A subcellular prefractionation protocol for minute amounts of mammalian cell cultures and tissue.

30 November 2018

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FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells.

30 November 2018

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Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment

30 November 2018

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Combinatorial synthesis of benztropine libraries and their evaluation as monoamine transporter inhibitors.

30 November 2018

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30 November 2018

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The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo

30 November 2018

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Interaction between glucocorticoid hormones, stress and psychostimulant drugs

30 November 2018

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Crystal structure of the glucocorticoid receptor ligand binding domain reveals a novel mode of receptor dimerization and coactivator recognition

30 November 2018

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Overexpression of the FK506-binding immunophilin FKBP51 is the common cause of glucocorticoid resistance in three New World primates

30 November 2018

1 reference

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Squirrel monkey immunophilin FKBP51 is a potent inhibitor of glucocorticoid receptor binding

30 November 2018

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The dopaminergic hyper-responsiveness of the shell of the nucleus accumbens is hormone-dependent

30 November 2018

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Novel N-substituted 3 alpha-[bis(4'-fluorophenyl)methoxy]tropane analogues: selective ligands for the dopamine transporter

30 November 2018

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Tissue distribution and abundance of human FKBP51, and FK506-binding protein that can mediate calcineurin inhibition

30 November 2018

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Suppression of glucocorticoid secretion and antipsychotic drugs have similar effects on the mesolimbic dopaminergic transmission.

30 November 2018

1 reference

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Corticosterone circadian secretion differentially facilitates dopamine-mediated psychomotor effect of cocaine and morphine.

30 November 2018

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Hyperpyrexia and coma due to overdose of benztropine

30 November 2018

1 reference

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Anticholinergic effects on memory: benztropine versus amantadine.

30 November 2018

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A Controlled Trial of Amantadine in Drug-Induced Extrapyramidal Disorders

30 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6126901

Serial serum drug concentrations and prolonged anticholinergic toxicity after benztropine (Cogentin) overdose

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29893552

12 December 2020

inferred from PubMed ID database lookup

Physostigmine temporarily and dramatically reversing acute mania

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29893552

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1021/ACSCHEMBIO.8B00454

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

PubMed publication ID

29893552

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29893552%20AND%20SRC:MED&resulttype=core&format=json