Cryo-EM structure of substrate-bound human telomerase holoenzyme. (Q52716589)

PubMed publication ID

29695869

6 May 2018

http://europepmc.org/abstract/MED/29695869

title

Cryo-EM structure of substrate-bound human telomerase holoenzyme (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6223129&resulttype=core&format=json

cryogenic electron microscopy

12 May 2020

main subject

0 references

Telomerase reverse transcriptase

1 reference

WD repeat containing antisense to TP53

1 reference

NHP2 ribonucleoprotein

1 reference

GAR1 ribonucleoprotein

1 reference

Dyskerin pseudouridine synthase 1

1 reference

NOP10 ribonucleoprotein

1 reference

telomere maintenance via telomerase

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

0 references

Eva Nogales

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Thi Hoang Duong Nguyen

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jane Tam

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Daniel Toso

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Kathleen Collins

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

language of work or name

English

0 references

publication date

25 April 2018

1 reference

PubMed publication ID

29695869

6 May 2018

http://europepmc.org/abstract/MED/29695869

published in

Nature

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

557

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

7704

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

190-195

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

Complex interactions between the DNA-damage response and mammalian telomeres

11 June 2020

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Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation

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Human telomerase contains two cooperating telomerase RNA molecules

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Structure of active dimeric human telomerase

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Specificity and stoichiometry of subunit interactions in the human telomerase holoenzyme assembled in vivo

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Structure of Tetrahymena telomerase reveals previously unknown subunits, functions, and interactions

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The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification

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RNA-guided isomerization of uridine to pseudouridine--pseudouridylation

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Protein composition of catalytically active human telomerase from immortal cells

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Crystal structure of an H/ACA box ribonucleoprotein particle.

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Purification of human telomerase complexes identifies factors involved in telomerase biogenesis and telomere length regulation

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Human telomerase RNA accumulation in Cajal bodies facilitates telomerase recruitment to telomeres and telomere elongation

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Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex

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Minimized human telomerase maintains telomeres and resolves endogenous roles of H/ACA proteins, TCAB1, and Cajal bodies

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7 January 2021

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7 January 2021

The architecture of Tetrahymena telomerase holoenzyme

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7 January 2021

A Single Templating RNA in Yeast Telomerase

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7 January 2021

Single-molecule analysis of human telomerase monomer

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7 January 2021

Structural basis for protein-RNA recognition in telomerase

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7 January 2021

Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase

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Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.

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Solution structure and dynamics of the wild-type pseudoknot of human telomerase RNA

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7 January 2021

Architecture of human telomerase RNA.

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Structural and functional characterization of human telomerase RNA processing and cajal body localization signals

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Structure and folding of the Tetrahymena telomerase RNA pseudoknot

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7 January 2021

Structural basis of template-boundary definition in Tetrahymena telomerase

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7 January 2021

Human telomerase activation requires two independent interactions between telomerase RNA and telomerase reverse transcriptase

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A critical stem-loop structure in the CR4-CR5 domain of mammalian telomerase RNA.

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RNA-protein binding interface in the telomerase ribonucleoprotein

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Secondary structure of vertebrate telomerase RNA

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PubMed

https://pubmed.ncbi.nlm.nih.gov/29695869

12 December 2020

inferred from PubMed ID database lookup

Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29695869

12 December 2020

inferred from PubMed ID database lookup

Telomerase Regulation from Beginning to the End

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29695869

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/S41586-018-0062-X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

11 June 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

PubMed publication ID

29695869

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29695869%20AND%20SRC:MED&resulttype=core&format=json