Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors (Q45299117)

14 May 2018

title

Correction of hemophilia B in canine and murine models using recombinant adeno-associated viral vectors (English)

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14 May 2018

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Snyder RO

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Miao C

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Meuse L

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Tubb J

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Donahue BA

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Lin HF

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Stafford DW

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Patel S

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Thompson AR

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Nichols T

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Read MS

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Bellinger DA

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Brinkhous KM

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Kay MA

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language of work or name

English

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publication date

1 January 1999

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14 May 2018

published in

Nature Medicine

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volume

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issue

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page(s)

64-70

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Huntington's disease: translating a CAG repeat into a pathogenic mechanism

cites work

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Huntington's disease gene (IT15) is widely expressed in human and rat tissues

21 January 2018

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Ataxin-1 nuclear localization and aggregation: role in polyglutamine-induced disease in SCA1 transgenic mice

21 January 2018

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

21 January 2018

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

21 January 2018

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Intranuclear neuronal inclusions in Huntington's disease and dentatorubral and pallidoluysian atrophy: correlation between the density of inclusions and IT15 CAG triplet repeat length

21 January 2018

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Mitochondrial function in Huntington's disease: clues for pathogenesis and prospects for treatment

21 January 2018

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Mitochondrial defect in Huntington's disease caudate nucleus

21 January 2018

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Energy metabolism defects in Huntington's disease and effects of coenzyme Q10.

21 January 2018

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Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.

21 January 2018

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Biochemical abnormalities and excitotoxicity in Huntington's disease brain.

21 January 2018

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Complex I defect in muscle from patients with Huntington's disease.

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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The mitochondrial death/life regulator in apoptosis and necrosis

21 January 2018

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Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.

21 January 2018

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Glutamate-induced neuronal death: A succession of necrosis or apoptosis depending on mitochondrial function

21 January 2018

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Expression analysis of the ataxin-1 protein in tissues from normal and spinocerebellar ataxia type 1 individuals

21 January 2018

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Mitochondrial permeability transition is a central coordinating event of apoptosis

21 January 2018

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Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel.

21 January 2018

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Immunophilins and nervous system

21 January 2018

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Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

21 January 2018

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Role of Ced-3/ICE-family proteases in staurosporine-induced programmed cell death

21 January 2018

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Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

21 January 2018

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Caspase-8 is required for cell death induced by expanded polyglutamine repeats.

21 January 2018

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Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

21 January 2018

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In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease.

21 January 2018

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Aberrant expression of bcl-2 gene family in Down's syndrome brains

21 January 2018

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Glyceraldehyde-3-phosphate dehydrogenase: nuclear translocation participates in neuronal and nonneuronal cell death

21 January 2018

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Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

21 January 2018

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/13518

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14 May 2018

Dimensions Publication ID

1034835522

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14 May 2018