ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response (Q28488177)

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Robert Davies

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Shareef A Nahas

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Christina Brown

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Rashmi Tunuguntla

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Richard A Gatti

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Hailiang Hu

Creative Commons Attribution 4.0 International

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language of work or name

English

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publication date

May 2013

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e1003505

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start time

16 May 2013

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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Targeting DNA-PKcs and ATM with miR-101 sensitizes tumors to radiation

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ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

19 March 2017

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DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

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Direct regulation of CREB transcriptional activity by ATM in response to genotoxic stress

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Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM

19 March 2017

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Endogenous human microRNAs that suppress breast cancer metastasis

7 April 2017

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Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma

7 April 2017

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BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex

29 September 2017

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Comprehensive profiling of radiosensitive human cell lines with DNA damage response assays identifies the neutral comet assay as a potential surrogate for clonogenic survival

29 September 2017

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Defective DNA double-strand break repair in pediatric systemic lupus erythematosus

29 September 2017

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Assessing 'radiosensitivity' with kinetic profiles of γ-H2AX, 53BP1 and BRCA1 foci

29 September 2017

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Homozygous deficiency of ubiquitin-ligase ring-finger protein RNF168 mimics the radiosensitivity syndrome of ataxia-telangiectasia

29 September 2017

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The ATM kinase induces microRNA biogenesis in the DNA damage response.

29 September 2017

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MicroRNA-335 inhibits tumor reinitiation and is silenced through genetic and epigenetic mechanisms in human breast cancer

29 September 2017

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MicroRNAs: new players in the DNA damage response

29 September 2017

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Transforming growth factor-β regulates the sphere-initiating stem cell-like feature in breast cancer through miRNA-181 and ATM.

29 September 2017

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DNA damage and decisions: CtIP coordinates DNA repair and cell cycle checkpoints

29 September 2017

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ATM is down-regulated by N-Myc-regulated microRNA-421.

29 September 2017

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BRCA1 and its toolbox for the maintenance of genome integrity

29 September 2017

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Assembly of checkpoint and repair machineries at DNA damage sites

29 September 2017

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Cdk1 participates in BRCA1-dependent S phase checkpoint control in response to DNA damage

29 September 2017

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Clinical radiation sensitivity with DNA repair disorders: an overview

29 September 2017

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CtIP-BRCA1 modulates the choice of DNA double-strand-break repair pathway throughout the cell cycle.

29 September 2017

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Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer

29 September 2017

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An integrative genomic approach reveals coordinated expression of intronic miR-335, miR-342, and miR-561 with deregulated host genes in multiple myeloma

29 September 2017

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ATM gene mutations result in both recessive and dominant expression phenotypes of genes and microRNAs

29 September 2017

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Cell cycle-dependent complex formation of BRCA1.CtIP.MRN is important for DNA double-strand break repair.

29 September 2017

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DNA damage signalling guards against activated oncogenes and tumour progression

29 September 2017

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Ctp1/CtIP and the MRN complex collaborate in the initial steps of homologous recombination

29 September 2017

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Methylation of the ATM promoter in glioma cells alters ionizing radiation sensitivity

29 September 2017

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BRCA1 regulates RAD51 function in response to DNA damage and suppresses spontaneous sister chromatid replication slippage: implications for sister chromatid cohesion, genome stability, and carcinogenesis

29 September 2017

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Correction of ATM gene function by aminoglycoside-induced read-through of premature termination codons

29 September 2017

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Early diagnosis of ataxia-telangiectasia using radiosensitivity testing

29 September 2017

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Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line

29 September 2017

1 reference

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Involvement of Brca1 in S-phase and G(2)-phase checkpoints after ionizing irradiation

29 September 2017

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Four radiation hypersensitivity cases and their implications for clinical radiotherapy

29 September 2017

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Effect of ionizing radiation on DNA synthesis in ataxia telangiectasia cells.

29 September 2017

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Radiosensitivity in ataxia-telangiectasia: a new explanation

29 September 2017

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ATM is a target for positive regulation by E2F-1.

29 September 2017

1 reference

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The ATM-mediated DNA-damage response: taking shape.

2 June 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003505