ATM is a target for positive regulation by E2F-1. (Q42806424)

7 November 2017

title

ATM is a target for positive regulation by E2F-1. (English)

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7 November 2017

Eli Berkovich

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7 November 2017

Doron Ginsberg

series ordinal

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7 November 2017

language of work or name

English

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publication date

1 January 2003

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7 November 2017

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7 November 2017

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7 November 2017

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7 November 2017

page(s)

161-167

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Enhanced phosphorylation of p53 by ATM in response to DNA damage

7 November 2017

cites work

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Ras induces elevation of E2F-1 mRNA levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

A gene transcribed from the bidirectional ATM promoter coding for a serine rich protein: amino acid sequence, structure and expression studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

The regulation of E2F by pRB-family proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

p53 down-regulates CHK1 through p21 and the retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

The retinoblastoma gene product protects E2F-1 from degradation by the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

The structure and organization of the human NPAT gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Identification and characterization of a new gene physically linked to the ATM gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Role for E2F in control of both DNA replication and mitotic functions as revealed from DNA microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Expression of transcription factor E2F1 induces quiescent cells to enter S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

ATM associates with and phosphorylates p53: mapping the region of interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

The subcellular localization of E2F-4 is cell-cycle dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Induction of DNA synthesis and apoptosis are separable functions of E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

E2Fs up-regulate expression of genes involved in DNA replication, DNA repair and mitosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

E2F1 induces phosphorylation of p53 that is coincident with p53 accumulation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

ARF differentially modulates apoptosis induced by E2F1 and Myc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

ATM and ATR: networking cellular responses to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

p19(ARF) is dispensable for oncogenic stress-induced p53-mediated apoptosis and tumor suppression in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

CDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Regulation of BRCA1 expression by the Rb-E2F pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Multiple members of the E2F transcription factor family are the products of oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

Myc signaling via the ARF tumor suppressor regulates p53-dependent apoptosis and immortalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

E2F1 overexpression in quiescent fibroblasts leads to induction of cellular DNA synthesis and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

inferred from DOI database lookup

7 January 2021

based on heuristic

Stress signals induce transcriptionally inactive E2F-1 independently of p53 and Rb

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

inferred from DOI database lookup

7 January 2021

based on heuristic

ARF is not required for apoptosis in Rb mutant mouse embryos

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1206144

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.ONC.1206144

1 reference

Dimensions Publication ID

7 November 2017

1043155438

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1 reference