Summary: It is known that self-adjoint Hamiltonians with purely discrete eigenvalues can be written as (infinite) linear combination of mutually orthogonal projectors with eigenvalues as coefficients of the expansion. The projectors are defined by the eigenvectors of the Hamiltonians. In some recent papers, this expansion has been extended to the case in which these eigenvectors form a Riesz basis or, more recently, a \(\mathcal{D}\)-quasi basis [the first author et al., J. Math. Phys. 59, No. 3, 033506, 13 p. (2018; Zbl 1466.47018); with G. Bellomonte, J. Phys. A, Math. Theor. 50, No. 14, Article ID 145203, 20 p. (2017; Zbl 1364.81123)], rather than an orthonormal basis. Here we discuss what can be done when these sets are replaced by Parseval frames. This interest is motivated by physical reasons, and in particular by the fact that the mathematical Hilbert space where the physical system is originally defined, contains sometimes also states which cannot really be occupied by the physical system itself. In particular, we show what changes in the spectrum of the observables, when going from orthonormal bases to Parseval frames. In this perspective, we propose the notion of \(E\)-connection for observables. Several examples are discussed.