Hopf bifurcation analysis of delayed model of thymic infection with HIV-1. (English) Zbl 1278.92027
Summary: In this paper, a delayed differential equation model that describes infection of thymus with HIV-1 is considered. We first investigate the existence and stability of the equilibria and then we study the effect of the time delay on the stability of the infected equilibrium. Criteria are given to ensure that the infected equilibrium is asymptotically stable for all delay. Finally, by using a delay as a bifurcation parameter, the existence of Hopf bifurcation is investigated. Numerical simulations are presented to illustrate the analytical results.
MSC:
| 92C60 | Medical epidemiology |
| 34K18 | Bifurcation theory of functional-differential equations |
| 37N25 | Dynamical systems in biology |
References:
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