Summary: Commitments among agents are widely recognized as an important basis for organizing interactions in multiagent systems. We develop an approach for formally representing and reasoning about commitments in the event calculus. We apply and evaluate this approach in the context of protocols, which represent the interactions allowed among communicating agents. Protocols are essential in applications such as electronic commerce where it is necessary to constrain the behaviors of autonomous agents. Traditional approaches, which model protocols merely in terms of action sequences, limit the flexibility of the agents in executing the protocols. By contrast, by formally representing commitments, we can specify the content of the protocols through the agents’ commitments to one another. In representing commitments in the event calculus, we formalize commitment operations and domain-independent reasoning rules as axioms to capture the evolution of commitments. We also provide a means to specify protocol-specific axioms through the agents’ actions. These axioms enable agents to reason about their actions explicitly to flexibly accommodate the exceptions and opportunities that may arise at run time. This reasoning is implemented using an event calculus planner that helps determine flexible execution paths that respect the given protocol specifications.