×

Optimal diallel cross designs for estimation of heritability. (English) Zbl 1020.62063

Summary: Diallel crosses as mating designs are used to study the genetic properties of inbred lines in plant breeding experiments. Most of the theory of optimal diallel cross designs is based on standard linear model assumptions where the general combining ability effects are taken as fixed. In many practical situations, this assumption may not be tenable since we are studying only a sample of inbred lines from a possibly large hypothetical population. A random effects model is proposed that allows us to first estimate the variance components and then obtain the variances of the estimates.
We address the issue of optimal designs in this context by considering \(A\)-optimality criteria. We obtain designs that are \(A\)-optimal for the estimation of heritability in the sense that the designs minimize the sum of the variances of the estimates of the variance components. The approach leads to certain connections with the optimization problem under the fixed effects model. Some numerical illustrations are given.

MSC:

62K05 Optimal statistical designs
62P10 Applications of statistics to biology and medical sciences; meta analysis
62J10 Analysis of variance and covariance (ANOVA)
Full Text: DOI

References:

[1] Das, A.; Dean, A. M.; Gupta, S., On optimality of some partial diallel cross designs, Sankhyā B, 60, 511-524 (1998) · Zbl 0974.62055
[2] Das, A.; Dey, A.; Dean, A. M., Optimal block designs for diallel cross experiments, Statist. Probab. Lett., 36, 427-436 (1998) · Zbl 0888.62076
[3] Das, K.; Meneghini, Q.; Giri, N. C., Inadmissibility of an estimator for the ratio of variance components, Statist. Probab. Lett., 10, 151-157 (1990) · Zbl 0716.62007
[4] Dey, A.; Midha, C. K., Optimal block designs for diallel crossses, Biometrika, 83, 484-489 (1996) · Zbl 0864.62051
[5] Falconer, D. S., Introduction to Quantitative Genetics (1991), Oliver and Boyd: Oliver and Boyd Edinburgh
[6] Griffing, B., Concepts of general and specific combining ability in relation to diallel crossing systems, Austar. J. Bio. Sci., 9, 463-493 (1956)
[7] Gupta, S.; Kageyama, S., Optimal complete diallel crosses, Biometrika, 81, 420-424 (1994) · Zbl 0825.62642
[8] Kempthorne, O., An Introduction to Genetic Statistic (1969), The Iowa State University Press: The Iowa State University Press Iowa · Zbl 0214.19402
[9] Loh, W., Improved estimators for ratio of variance components, J. Amer. Statist. Assoc., 81, 699-702 (1986) · Zbl 0625.62055
[10] Mayo, O., The Theory of Plant Breeding (1980), Clarendon Press: Clarendon Press Oxford
[11] Morgan, J. P.; Preece, D. A.; Rees, D. H., Nested balanced incomplete block designs, Discrete Math., 231, 351-389 (2001) · Zbl 0988.05018
[12] Mukerjee, R., Optimal partial diallel crosses, Biometrika, 84, 939-948 (1997) · Zbl 0892.62056
[13] Preece, D. A., Nested balanced incomplete block designs, Biometrika, 54, 479-486 (1967)
[14] Searle, S. R.; Casella, G.; McCulloch, C. E., Variance Components (1992), Wiley: Wiley New York · Zbl 0850.62007
[15] Singh, M.; Hinkelmann, K., Partial diallel crosses in incomplete blocks, Biometrics, 51, 1302-1314 (1995) · Zbl 0875.62512
This reference list is based on information provided by the publisher or from digital mathematics libraries. Its items are heuristically matched to zbMATH identifiers and may contain data conversion errors. In some cases that data have been complemented/enhanced by data from zbMATH Open. This attempts to reflect the references listed in the original paper as accurately as possible without claiming completeness or a perfect matching.