×

Nonparametric Bayesian bioassay with prior constraints on the shape of the potency curve. (English) Zbl 0787.62115

Summary: We consider the problem of implementing nonparametric Bayesian analysis of bioassay problems when the prior constrains the form of the potency curve (for example, to be convex, concave or ogive). Sampling based approaches to calculating posterior features of interest are detailed and illustrated. Extensions to prior constraints on hazard rates are outlined.

MSC:

62P10 Applications of statistics to biology and medical sciences; meta analysis
62G05 Nonparametric estimation
62F15 Bayesian inference
Full Text: DOI