Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae (Q98513594)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

title

Adaptation to the cervical environment is associated with increased antibiotic susceptibility in Neisseria gonorrhoeae (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

main subject

Neisseria gonorrhoeae

object named as

Neisseria gonorrhoeae

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

Simon R Harris

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

George Taiaroa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

Magnus Unemo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

Daniel H F Rubin

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

Yi Wang

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

publication date

17 August 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

published in

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

19 August 2020

page(s)

4126

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:32807804%20AND%20SRC:MED&resulttype=core&format=json

Azithromycin Susceptibility Among Neisseria gonorrhoeae Isolates and Seasonal Macrolide Use

19 August 2020

cites work

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Deciphering the Impact of Bystander Selection for Antibiotic Resistance in Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

The impact of antimicrobials on gonococcal evolution

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Antimicrobial resistance in Neisseria gonorrhoeae in the 21st century: past, evolution, and future

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Azithromycin Resistance through Interspecific Acquisition of an Epistasis-Dependent Efflux Pump Component and Transcriptional Regulator in Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like Efflux Pump Locus

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Neisseria gonorrhoeae host adaptation and pathogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Antimicrobial resistance in Neisseria gonorrhoeae: Global surveillance and a call for international collaborative action

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genomic Epidemiology of Gonococcal Resistance to Extended-Spectrum Cephalosporins, Macrolides, and Fluoroquinolones in the United States, 2000-2013

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genomic surveillance of Neisseria gonorrhoeae to investigate the distribution and evolution of antimicrobial-resistance determinants and lineages

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

WGS to predict antibiotic MICs for Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Equations To Predict Antimicrobial MICs in Neisseria gonorrhoeae Using Molecular Antimicrobial Resistance Determinants

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Evaluation of parameters affecting performance and reliability of machine learning-based antibiotic susceptibility testing from whole genome sequencing data

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Identifying lineage effects when controlling for population structure improves power in bacterial association studies

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

pyseer: a comprehensive tool for microbial pangenome-wide association studies

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

A fast and agnostic method for bacterial genome-wide association studies: Bridging the gap between k-mers and genetic events

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Applications of genomics to slow the spread of multidrug-resistant Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Overexpression of the MtrC-MtrD-MtrE efflux pump due to an mtrR mutation is required for chromosomally mediated penicillin resistance in Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Importance of multidrug efflux pumps in the antimicrobial resistance property of clinical multidrug-resistant isolates of Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Loss-of-function mutations in the mtr efflux system of Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genetic variation regulates the activation and specificity of Restriction-Modification systems in Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Mutations to increased antibiotic sensitivity in naturally-occurring gonococci

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Emergence and evolution of internationally disseminated cephalosporin-resistant Neisseria gonorrhoeae clones from 1995 to 2005 in Japan

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

The MtrCDE Efflux Pump Contributes to Survival of From Human Neutrophils and Their Antimicrobial Components

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Regulation of the MtrC-MtrD-MtrE efflux-pump system modulates the in vivo fitness of Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Clinically relevant mutations that cause derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux pump system confer different levels of antimicrobial resistance and in vivo fitness

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

MtrR modulates rpoH expression and levels of antimicrobial resistance in Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Gonococcal MtrE and its surface-expressed Loop 2 are immunogenic and elicit bactericidal antibodies

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Bridging of Neisseria gonorrhoeae lineages across sexual networks in the HIV pre-exposure prophylaxis era

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Induction of the mtrCDE-encoded efflux pump system of Neisseria gonorrhoeae requires MtrA, an AraC-like protein

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Whole-Genome Sequencing of a Large Panel of Contemporary Neisseria gonorrhoeae Clinical Isolates Indicates that a Wild-Type mtrA Gene Is Common: Implications for Inducible Antimicrobial Resistance

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Multicomponent drug efflux complexes: architecture and mechanism of assembly

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

The farAB-encoded efflux pump mediates resistance of gonococci to long-chained antibacterial fatty acids

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

FarR regulates the farAB-encoded efflux pump of Neisseria gonorrhoeae via an MtrR regulatory mechanism

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

The NorM efflux pump of Neisseria gonorrhoeae and Neisseria meningitidis recognizes antimicrobial cationic compounds

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Characterization of the MacA-MacB efflux system in Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Epidemic meningitis, meningococcaemia, and Neisseria meningitidis

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genomic epidemiology of age-associated meningococcal lineages in national surveillance: an observational cohort study

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Notes from the Field: Increase in Neisseria meningitidis-Associated Urethritis Among Men at Two Sentinel Clinics - Columbus, Ohio, and Oakland County, Michigan, 2015.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Expansion of a urethritis-associated Neisseria meningitidis clade in the United States with concurrent acquisition of N. gonorrhoeae alleles.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Emergence of a new Neisseria meningitidis clonal complex 11 lineage 11.2 clade as an effective urogenital pathogen

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genetic characterisation of Neisseria gonorrhoeae resistant to both ceftriaxone and azithromycin

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Transient Silencing of Antibiotic Resistance by Mutation Represents a Significant Potential Source of Unanticipated Therapeutic Failure

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Gonococcal strains from homosexual men have outer membranes with reduced permeability to hydrophobic molecules

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Missense mutations that alter the DNA-binding domain of the MtrR protein occur frequently in rectal isolates of Neisseria gonorrhoeae that are resistant to faecal lipids

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

MpeR regulates the mtr efflux locus in Neisseria gonorrhoeae and modulates antimicrobial resistance by an iron-responsive mechanism

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Transcriptome Analysis of Neisseria gonorrhoeae during Natural Infection Reveals Differential Expression of Antibiotic Resistance Determinants between Men and Women.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Multidrug efflux pumps: structure, function and regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Efflux unbalance in Pseudomonas aeruginosa isolates from cystic fibrosis patients.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Mechanisms of intrinsic resistance and acquired susceptibility of Pseudomonas aeruginosa isolated from cystic fibrosis patients to temocillin, a revived antibiotic

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Hyperglycaemia and Pseudomonas aeruginosa acidify cystic fibrosis airway surface liquid by elevating epithelial monocarboxylate transporter 2 dependent lactate-H+ secretion

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Sequence-Specific Targeting of Bacterial Resistance Genes Increases Antibiotic Efficacy

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Could Dampening Expression of the Neisseria gonorrhoeae mtrCDE-Encoded Efflux Pump Be a Strategy To Preserve Currently or Resurrect Formerly Used Antibiotics To Treat Gonorrhea?

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Failure of azithromycin therapy in gonorrhea and discorrelation with laboratory test parameters.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Qualimap: evaluating next-generation sequencing alignment data.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Pilon: an integrated tool for comprehensive microbial variant detection and genome assembly improvement

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

SPAdes: a new genome assembly algorithm and its applications to single-cell sequencing

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Prokka: rapid prokaryotic genome annotation

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Roary: rapid large-scale prokaryote pan genome analysis

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Piggy: a rapid, large-scale pan-genome analysis tool for intergenic regions in bacteria.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Interactive Tree Of Life (iTOL) v4: recent updates and new developments

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Rapid phylogenetic analysis of large samples of recombinant bacterial whole genome sequences using Gubbins.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Basic local alignment search tool

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

MAFFT: a novel method for rapid multiple sequence alignment based on fast Fourier transform

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Fast hierarchical Bayesian analysis of population structure

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Use of whole-genome sequencing data to analyze 23S rRNA-mediated azithromycin resistance.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Rationale for a Neisseria gonorrhoeae Susceptible Only Interpretive Breakpoint for Azithromycin

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Biopython: freely available Python tools for computational molecular biology and bioinformatics

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genetic Manipulation of Neisseria gonorrhoeae

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Whole-genome phylogenomic heterogeneity of Neisseria gonorrhoeae isolates with decreased cephalosporin susceptibility collected in Canada between 1989 and 2013.

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genomic Epidemiology and Molecular Resistance Mechanisms of Azithromycin-Resistant Neisseria gonorrhoeae in Canada from 1997 to 2014

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Population structure of Neisseria gonorrhoeae based on whole genome data and its relationship with antibiotic resistance

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Genomic epidemiology of Neisseria gonorrhoeae with reduced susceptibility to cefixime in the USA: a retrospective observational study

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Whole-genome sequencing reveals transmission of gonococcal antibiotic resistance among men who have sex with men: an observational study

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021

Open-access bacterial population genomics: BIGSdb software, the PubMLST.org website and their applications

1 reference

https://api.crossref.org/works/10.1038%2FS41467-020-17980-1

7 January 2021