Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner (Q91882654)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31305993%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

title

Fluoxetine Inhibits Enterovirus Replication by Targeting the Viral 2C Protein in a Stereospecific Manner (English)

1 reference

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25 April 2020

1 reference

Jeroen R.P.M. Strating

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25 April 2020

1 reference

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25 April 2020

1 reference

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Frank J. M. van Kuppeveld

25 April 2020

1 reference

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25 April 2020

Lisa Bauer

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25 April 2020

Roberto Manganaro

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25 April 2020

Birgit Zonsics

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25 April 2020

Priscila El Kazzi

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25 April 2020

Moira Lorenzo Lopez

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25 April 2020

Rachel Ulferts

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25 April 2020

Clara van Hoey

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25 April 2020

Maria J Maté

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25 April 2020

Bruno Coutard

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25 April 2020

publication date

31 July 2019

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25 April 2020

published in

ACS Infectious Diseases

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25 April 2020

volume

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25 April 2020

issue

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25 April 2020

page(s)

1609-1623

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Safety, tolerability, and efficacy of fluoxetine as an antiviral for acute flaccid myelitis

25 April 2020

cites work

1 reference

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Screening of a Library of FDA-Approved Drugs Identifies Several Enterovirus Replication Inhibitors That Target Viral Protein 2C

23 February 2021

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Discovery of Structurally Diverse Small-Molecule Compounds with Broad Antiviral Activity against Enteroviruses

23 February 2021

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Replication and Inhibitors of Enteroviruses and Parechoviruses

23 February 2021

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Human Enterovirus Nonstructural Protein 2CATPase Functions as Both an RNA Helicase and ATP-Independent RNA Chaperone

23 February 2021

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Cholesterol shuttling is important for RNA replication of coxsackievirus B3 and encephalomyocarditis virus.

23 February 2021

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Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein

23 February 2021

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Fluoxetine a novel anti-hepatitis C virus agent via ROS-, JNK-, and PPARβ/γ-dependent pathways

23 February 2021

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Identification of a series of compounds with potent antiviral activity for the treatment of enterovirus infections

23 February 2021

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Assessment of Dengue virus helicase and methyltransferase as targets for fragment-based drug discovery

23 February 2021

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A C-terminal, cysteine-rich site in poliovirus 2C(ATPase) is required for morphogenesis

23 February 2021

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A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ.

23 February 2021

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Selective serotonin reuptake inhibitor fluoxetine inhibits replication of human enteroviruses B and D by targeting viral protein 2C.

23 February 2021

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23 February 2021

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Fluoxetine is a potent inhibitor of coxsackievirus replication

23 February 2021

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Enterovirus 71 2C protein inhibits TNF-α-mediated activation of NF-κB by suppressing IκB kinase β phosphorylation.

23 February 2021

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Direct interaction between two viral proteins, the nonstructural protein 2C and the capsid protein VP3, is required for enterovirus morphogenesis

23 February 2021

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23 February 2021

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Role of annexin A2 in the production of infectious hepatitis C virus particles

23 February 2021

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23 February 2021

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Poliovirus 2C Protein Forms Homo-oligomeric Structures Required for ATPase Activity

23 February 2021

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23 February 2021

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The generalized Born/volume integral implicit solvent model: estimation of the free energy of hydration using London dispersion instead of atomic surface area

23 February 2021

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23 February 2021

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Reticulon 3 Binds the 2C Protein of Enterovirus 71 and Is Required for Viral Replication

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Interaction of poliovirus-encoded 2C/2BC polypeptides with the 3' terminus negative-strand cloverleaf requires an intact stem-loop b

23 February 2021

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The antiviral compound 5-(3,4-dichlorophenyl) methylhydantoin inhibits the post-synthetic cleavages and the assembly of poliovirus in a cell-free system

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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Dependence of echovirus 9 on the enterovirus RNA replication inhibitor 2-(alpha-Hydroxybenzyl)-benzimidazole maps to nonstructural protein 2C

23 February 2021

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Characterization of the nucleoside triphosphatase activity of poliovirus protein 2C reveals a mechanism by which guanidine inhibits poliovirus replication

23 February 2021

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23 February 2021

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Poliovirus 2C protein determinants of membrane binding and rearrangements in mammalian cells

23 February 2021

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23 February 2021

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Synchronous replication of poliovirus RNA: initiation of negative-strand RNA synthesis requires the guanidine-inhibited activity of protein 2C.

23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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23 February 2021

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MAB, a generally applicable molecular force field for structure modelling in medicinal chemistry.

23 February 2021

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Molecular structure of fluoxetine hydrochloride, a highly selective serotonin-uptake inhibitor

23 February 2021

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Isolation of poliovirus 2C mutants defective in viral RNA synthesis

23 February 2021

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An intragenic revertant of a poliovirus 2C mutant has an uncoating defect

23 February 2021

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A Method to Identify Protein Sequences That Fold into a Known Three-Dimensional Structure

23 February 2021

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23 February 2021

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Analysis of the functional significance of amino acid residues in the putative NTP-binding pattern of the poliovirus 2C protein

23 February 2021

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A SIMPLE METHOD OF ESTIMATING FIFTY PER CENT ENDPOINTS

23 February 2021

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Identifiers

DOI

10.1021/ACSINFECDIS.9B00179

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31305993%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31305993%20AND%20SRC:MED&resulttype=core&format=json

25 April 2020

PubMed publication ID

31305993

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:31305993%20AND%20SRC:MED&resulttype=core&format=json