Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer (Q77565725)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818174%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

review article

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title

Differential molecular interactions of beta-catenin and plakoglobin in adhesion, signaling and cancer (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818174%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

main subject

molecular interaction

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818174%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

B Geiger

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6 December 2019

publication date

1 October 1998

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Current Opinion in Cell Biology

6 December 2019

published in

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6 December 2019

volume

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6 December 2019

issue

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6 December 2019

page(s)

629-639

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818174%20AND%20SRC:MED&resulttype=core&format=json

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

6 December 2019

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7 January 2021

Serine phosphorylation-regulated ubiquitination and degradation of beta-catenin

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7 January 2021

Regulation of beta-catenin levels and localization by overexpression of plakoglobin and inhibition of the ubiquitin-proteasome system

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7 January 2021

Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein

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7 January 2021

Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

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7 January 2021

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

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7 January 2021

Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

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7 January 2021

Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos

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7 January 2021

Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

1 reference

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7 January 2021

Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

1 reference

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7 January 2021

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

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7 January 2021

Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

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7 January 2021

Axis determination in Xenopus involves biochemical interactions of axin, glycogen synthase kinase 3 and beta-catenin.

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7 January 2021

GBP, an inhibitor of GSK-3, is implicated in Xenopus development and oncogenesis

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7 January 2021

Wingless signaling: the inconvenient complexities of life

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7 January 2021

The dishevelled protein is modified by wingless signaling in Drosophila

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7 January 2021

Analysis of Dishevelled signalling pathways during Xenopus development.

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7 January 2021

Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin

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7 January 2021

Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin

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7 January 2021

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

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7 January 2021

Functional interaction of beta-catenin with the transcription factor LEF-1

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7 January 2021

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

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7 January 2021

LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

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7 January 2021

An in vivo structure-function study of armadillo, the beta-catenin homologue, reveals both separate and overlapping regions of the protein required for cell adhesion and for wingless signaling

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7 January 2021

Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

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7 January 2021

Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

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7 January 2021

Wnt-1 induces growth, cytosolic beta-catenin, and Tcf/Lef transcriptional activation in Rat-1 fibroblasts

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7 January 2021

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila.

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7 January 2021

LEF-1/TCF proteins mediate wnt-inducible transcription from the Xenopus nodal-related 3 promoter

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7 January 2021

The segment polarity gene armadillo encodes a functionally modular protein that is the Drosophila homolog of human plakoglobin.

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7 January 2021

Plakoglobin and beta-catenin: distinct but closely related

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7 January 2021

The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar properties

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7 January 2021

Identification of Plakoglobin Domains Required for Association with N-cadherin and α-Catenin

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7 January 2021

beta-Catenin associates with the actin-bundling protein fascin in a noncadherin complex

1 reference

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7 January 2021

E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton

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7 January 2021

Suppression of tumorigenicity by plakoglobin: an augmenting effect of N-cadherin.

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7 January 2021

Targeted mutation of plakoglobin in mice reveals essential functions of desmosomes in the embryonic heart

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7 January 2021

Embryonic heart and skin defects in mice lacking plakoglobin

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7 January 2021

Anterior axis duplication in Xenopus induced by the over-expression of the cadherin-binding protein plakoglobin

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7 January 2021

Localizing the adhesive and signaling functions of plakoglobin

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7 January 2021

Embryonic axis induction by the armadillo repeat domain of beta-catenin: evidence for intracellular signaling

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7 January 2021

Cytoplasmically anchored plakoglobin induces a WNT-like phenotype in Xenopus

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7 January 2021

Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus

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7 January 2021

Signaling and adhesion activities of mammalian beta-catenin and plakoglobin in Drosophila

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7 January 2021

Gut reaction to Wnt signaling in worms

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7 January 2021

Wnt signaling and an APC-related gene specify endoderm in early C. elegans embryos

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7 January 2021

Adenomatous polyposis coli tumor suppressor protein has signaling activity in Xenopus laevis embryos resulting in the induction of an ectopic dorsoanterior axis

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7 January 2021

A Drosophila homolog of the tumor suppressor gene adenomatous polyposis coli down-regulates beta-catenin but its zygotic expression is not essential for the regulation of Armadillo

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7 January 2021

Regulation of armadillo by a Drosophila APC inhibits neuronal apoptosis during retinal development

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7 January 2021

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7 January 2021

Wnt signaling polarizes an early C. elegans blastomere to distinguish endoderm from mesoderm

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7 January 2021

A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus

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7 January 2021

The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin

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7 January 2021

Three-dimensional structure of the armadillo repeat region of beta-catenin

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7 January 2021

Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus

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7 January 2021

Uncoupling cadherin-based adhesion from wingless signalling in Drosophila.

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7 January 2021

Expression of Wnt-1 in PC12 cells results in modulation of plakoglobin and E-cadherin and increased cellular adhesion

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7 January 2021

Wnt-1 modulates cell-cell adhesion in mammalian cells by stabilizing beta-catenin binding to the cell adhesion protein cadherin

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7 January 2021

Antagonism of cell adhesion by an alpha-catenin mutant, and of the Wnt-signaling pathway by alpha-catenin in Xenopus embryos.

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7 January 2021

Accumulation of Armadillo induced by Wingless, Dishevelled, and dominant-negative Zeste-White 3 leads to elevated DE-cadherin in Drosophila clone 8 wing disc cells

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7 January 2021

Cell adhesion and the integrin-linked kinase regulate the LEF-1 and beta-catenin signaling pathways

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7 January 2021

Roles of Armadillo, a Drosophila catenin, during central nervous system development.

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7 January 2021

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

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7 January 2021

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

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7 January 2021

Stabilization of beta-catenin by genetic defects in melanoma cell lines

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7 January 2021

Beta-catenin as oncogene: the smoking gun.

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7 January 2021

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

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7 January 2021

Expression cloning of oncogenes by retroviral transfer of cDNA libraries

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7 January 2021

The human plakoglobin gene localizes on chromosome 17q21 and is subjected to loss of heterozygosity in breast and ovarian cancers

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7 January 2021

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

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7 January 2021

Expression of wild-type alpha-catenin protein in cells with a mutant alpha-catenin gene restores both growth regulation and tumor suppressor activities

1 reference

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7 January 2021

10.1016/S0955-0674(98)80039-2

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818174%20AND%20SRC:MED&resulttype=core&format=json

6 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9818174%20AND%20SRC:MED&resulttype=core&format=json