p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression (Q58091439)

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article published in the Proceedings of the National Academy of Sciences of the United States of America

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English	p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression	article published in the Proceedings of the National Academy of Sciences of the United States of America

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1 May 2020

p53 mutants cooperate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumor progression (English)

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1 May 2020

tumor progression

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1 May 2020

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1 May 2020

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Ivano Amelio

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1 May 2020

Varvara Petrova

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1 May 2020

Rob A Cairns

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1 May 2020

Polina Vikhreva

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1 May 2020

Sara Nicolai

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1 May 2020

Alberto Marini

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1 May 2020

Alexey A Antonov

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1 May 2020

John Le Quesne

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1 May 2020

Juvenal D Baena Acevedo

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1 May 2020

Kate Dudek

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1 May 2020

Gabriella Sozzi

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1 May 2020

Ugo Pastorino

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1 May 2020

Richard A Knight

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1 May 2020

Tak W Mak

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31 October 2018

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1 May 2020

Proceedings of the National Academy of Sciences of the United States of America

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1 May 2020

115

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1 May 2020

46

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1 May 2020

E10869-E10878

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1 May 2020

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International

31 October 2018

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April 2022 Public Data File from Crossref

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Hypoxia induces accumulation of p53 protein, but activation of a G1-phase checkpoint by low-oxygen conditions is independent of p53 status.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 inhibits hypoxia-inducible factor-stimulated transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA damage is a prerequisite for p53-mediated proteasomal degradation of HIF-1alpha in hypoxic cells and downregulation of the hypoxia marker carbonic anhydrase IX.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type VII collagen is required for Ras-driven human epidermal tumorigenesis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genome-wide analysis of p53 under hypoxic conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumour microenvironment: laminin 332 in squamous-cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blinded by the Light: The Growing Complexity of p53

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factors in physiology and medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 cooperates with ETS2 to promote etoposide resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53: one name, many proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

miR-24 triggers epidermal differentiation by controlling actin adhesion and cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 drives pancreatic cancer metastasis through cell-autonomous PDGF receptor β signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unravelling mechanisms of p53-mediated tumour suppression

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia and the extracellular matrix: drivers of tumour metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible factor 1α degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer: A piece of the p53 puzzle

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-induced p53 modulates both apoptosis and radiosensitivity via AKT

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

H3K9me3 facilitates hypoxia-induced p53-dependent apoptosis through repression of APAK.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The p53 family and the hypoxia-inducible factors (HIFs): determinants of cancer progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-Mediated Increases in L-2-hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia Induces Production of L-2-Hydroxyglutarate.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gain-of-function p53 mutants co-opt chromatin pathways to drive cancer growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SynTarget: an online tool to test the synergetic effect of genes on survival outcome in cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53MutaGene: an online tool to estimate the effect of p53 mutational status on gene regulation in cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic control of metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional Regulation by Wild-Type and Cancer-Related Mutant Forms of p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Putting p53 in Context

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutant p53 partners in crime

1 reference

https://pubmed.ncbi.nlm.nih.gov/30381462

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1808314115

1 reference

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1 May 2020

PMC publication ID

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Europe PubMed Central

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1 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

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1 May 2020

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