CD28/CTLA-4/B7 costimulatory pathway blockade affects regulatory T-cell function in autoimmunity (Q56895988)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25727069%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

CD28/CTLA-4/B7 costimulatory pathway blockade affects regulatory T-cell function in autoimmunity (English)

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1 March 2020

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1 March 2020

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1 March 2020

Ahmad Kasran

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1 March 2020

Jonathan Cremer

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1 March 2020

Yoo-Jin Kim

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1 March 2020

Louis Boon

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1 March 2020

Stefaan W Van Gool

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1 March 2020

language of work or name

English

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publication date

3 April 2015

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European Journal of Immunology

1 March 2020

published in

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volume

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issue

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1 March 2020

page(s)

1832-1841

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1 March 2020

cites work

The B7-CD28 superfamily

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Induction of immunologic tolerance for allogeneic hematopoietic cell transplantation

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Intracellular trafficking of CTLA-4 and focal localization towards sites of TCR engagement

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The emerging role of CTLA-4 as an immune attenuator

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CTLA-4 control over Foxp3+ regulatory T cell function

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Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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7 January 2021

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

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7 January 2021

Treatment of rheumatoid arthritis by selective inhibition of T-cell activation with fusion protein CTLA4Ig

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Abatacept for rheumatoid arthritis refractory to tumor necrosis factor alpha inhibition

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Rational development of LEA29Y (belatacept), a high-affinity variant of CTLA4-Ig with potent immunosuppressive properties.

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Belatacept: a novel immunosuppressive agent for kidney transplant recipients

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The role of B7 co-stimulation in activation and differentiation of CD4+ and CD8+ T cells

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7 January 2021

Deleterious effect of CTLA4-Ig on a Treg-dependent transplant model

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7 January 2021

CTLA4-Ig restores rejection of MHC class-II mismatched allografts by disabling IL-2-expanded regulatory T cells.

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7 January 2021

Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

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7 January 2021

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

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https://api.crossref.org/works/10.1002%2FEJI.201445190

7 January 2021

Cell-intrinsic and -extrinsic control of Treg-cell homeostasis and function revealed by induced CD28 deletion

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7 January 2021

https://api.crossref.org/works/10.1002%2FEJI.201445190

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7 January 2021

Long-term inhibition of murine experimental autoimmune encephalomyelitis using CTLA-4-Fc supports a key role for CD28 costimulation.

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7 January 2021

Kinetics and cellular origin of cytokines in the central nervous system: insight into mechanisms of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis

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Cytokines and effector T cell subsets causing autoimmune CNS disease

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GM-CSF: the secret weapon in the T(H)17 arsenal

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Interleukin-10 and the interleukin-10 receptor

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7 January 2021

Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis

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7 January 2021

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.

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7 January 2021

Pharmacokinetics of CTLA4Ig fusion protein in healthy volunteers and patients with rheumatoid arthritis

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7 January 2021

CD28 co-stimulation down regulates Th17 development

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https://api.crossref.org/works/10.1002%2FEJI.201445190

7 January 2021

Cutting edge: CTLA-4--B7 interaction suppresses Th17 cell differentiation

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201445190

7 January 2021

ICOS deficiency results in exacerbated IL-17 mediated experimental autoimmune encephalomyelitis.

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7 January 2021

Experimental optic neuritis induced by a demyelinating strain of mouse hepatitis virus.

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Mechanisms of primary axonal damage in a viral model of multiple sclerosis.

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7 January 2021

Identifiers

DOI

10.1002/EJI.201445190

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25727069%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25727069%20AND%20SRC:MED&resulttype=core&format=json