A constitutive BCL2 down-regulation aggravates the phenotype of PKD1-mutant-induced polycystic kidney disease. (Q47707521)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

title

A constitutive BCL2 down-regulation aggravates the phenotype of PKD1-mutant-induced polycystic kidney disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Laurence Duplomb

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Virginie Carmignac

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Julien Thevenon

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Ange-Line Bruel

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Olivier Bouchot

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Christel Thauvin-Robinet

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Patrick Callier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Guillaume Meurice

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Noémie Pata-Merci

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Romaric Loffroy

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

David Vandroux

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Romain D A Costa

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Laurence Faivre

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

publication date

1 December 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

published in

Human Molecular Genetics

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

page(s)

4680-4688

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation

31 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

The mystery of BCL2 family: Bcl-2 proteins and apoptosis: an update.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Substantial susceptibility of chronic lymphocytic leukemia to BCL2 inhibition: results of a phase I study of navitoclax in patients with relapsed or refractory disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Involvement of B-cell CLL/lymphoma 2 promoter methylation in cigarette smoke extract-induced emphysema

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

miR-15 and miR-16 induce apoptosis by targeting BCL2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

miR-181a/b significantly enhances drug sensitivity in chronic lymphocytic leukemia cells via targeting multiple anti-apoptosis genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Rescue of renal hypoplasia and cystic dysplasia in Bcl-2 -/- mice expressing Bcl-2 in ureteric bud derived epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Thirty years of BCL-2: translating cell death discoveries into novel cancer therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

DNA methylation and its basic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

A nonsense variant in HERC1 is associated with intellectual disability, megalencephaly, thick corpus callosum and cerebellar atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Biallelic HERC1 mutations in a syndromic form of overgrowth and intellectual disability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

A splice site mutation in HERC1 leads to syndromic intellectual disability with macrocephaly and facial dysmorphism: Further delineation of the phenotypic spectrum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

miR-181 targets multiple Bcl-2 family members and influences apoptosis and mitochondrial function in astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Role of apoptosis in the development of autosomal dominant polycystic kidney disease (ADPKD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

The pck rat: a new model that resembles human autosomal dominant polycystic kidney and liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Loss of PKD1 and loss of Bcl-2 elicit polycystic kidney disease through distinct mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

The genetics of vascular complications in autosomal dominant polycystic kidney disease (ADPKD).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Vascular complications in autosomal dominant polycystic kidney disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Transforming growth factor-beta signaling in thoracic aortic aneurysm development: a paradox in pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Apoptotic vascular smooth muscle cell depletion via BCL2 family of proteins in human ascending aortic aneurysm and dissection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Opposing effects of bim and bcl-2 on lung endothelial cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Attenuation of retinal endothelial cell migration and capillary morphogenesis in the absence of bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Bim is responsible for the inherent sensitivity of the developing retinal vasculature to hyperoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Attenuation of retinal vascular development and neovascularization during oxygen-induced ischemic retinopathy in Bcl-2-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Post-transcriptional and post-translational regulation of Bcl2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

miR-181a sensitizes resistant leukaemia HL-60/Ara-C cells to Ara-C by inducing apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

miR-181a sensitizes a multidrug-resistant leukemia cell line K562/A02 to daunorubicin by targeting BCL-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Identification of microRNA-181 by genome-wide screening as a critical player in EpCAM-positive hepatic cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

miR-181a is an intrinsic modulator of T cell sensitivity and selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Immuno-miRs: critical regulators of T-cell development, function and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

hsa-mir-181a and hsa-mir-181b function as tumor suppressors in human glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

MicroRNA-181a - a tale of discrepancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

miR-181a and miR-630 regulate cisplatin-induced cancer cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

Characterization of the inflammatory and apoptotic cells in the aortas of patients with ascending thoracic aortic aneurysms and dissections

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDX349

21 January 2018

Identifiers

DOI

10.1093/HMG/DDX349

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28973148%20AND%20SRC:MED&resulttype=core&format=json