CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation (Q45107882)

9 December 2017

title

CD98hc (SLC3A2) interaction with beta 1 integrins is required for transformation (English)

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9 December 2017

Neil C Henderson

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9 December 2017

Elizabeth A Collis

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9 December 2017

Alison C Mackinnon

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9 December 2017

Kenneth J Simpson

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9 December 2017

Christopher Haslett

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9 December 2017

Roy Zent

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9 December 2017

Mark Ginsberg

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9 December 2017

Tariq Sethi

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9 December 2017

language of work or name

English

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publication date

12 October 2004

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Journal of Biological Chemistry

9 December 2017

published in

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9 December 2017

volume

279

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9 December 2017

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9 December 2017

page(s)

54731-54741

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Analysis of the expression of the 4F2 surface antigen in normal and neoplastic fibroblastic human cells of embryonic and adult origin

9 December 2017

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Activated SRC oncogene phosphorylates R-ras and suppresses integrin activity

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Pro-adhesive and chemotactic activities of thrombospondin-1 for breast carcinoma cells are mediated by alpha3beta1 integrin and regulated by insulin-like growth factor-1 and CD98

21 January 2018

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Beta1 integrins show specific association with CD98 protein in low density membranes

21 January 2018

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Transformation of BALB3T3 cells caused by over-expression of rat CD98 heavy chain (HC) requires its association with light chain: mis-sense mutation in a cysteine residue of CD98HC eliminates its transforming activity.

21 January 2018

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Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts

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The cytoplasmic tyrosines of integrin subunit beta1 are involved in focal adhesion kinase activation

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24 Evaluation of chemical carcinogenicity by in vitro neoplastic transformation

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Distinct domains of CD98hc regulate integrins and amino acid transport

21 January 2018

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FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

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Mammary epithelial-specific expression of the integrin-linked kinase (ILK) results in the induction of mammary gland hyperplasias and tumors in transgenic mice.

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Focal adhesion kinase as a potential target in oncology

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Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

21 January 2018

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Identification and characterization of a new oncogene derived from the regulatory subunit of phosphoinositide 3-kinase

21 January 2018

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

21 January 2018

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4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer.

21 January 2018

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Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)

21 January 2018

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Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family

21 January 2018

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Functional heterodimeric amino acid transporters lacking cysteine residues involved in disulfide bond.

21 January 2018

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Ligand-specific activation of HER4/p180erbB4, a fourth member of the epidermal growth factor receptor family

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M408700200

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9 December 2017

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