NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo signalling pathway (Q42830266)

8 November 2017

title

NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo signalling pathway (English)

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8 November 2017

main subject

stem cell homeostasis

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Chin Ha Chung

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8 November 2017

Sung Jun Bae

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8 November 2017

Myungjin Kim

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8 November 2017

Sung-Hee Kim

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8 November 2017

Young Eun Kwon

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8 November 2017

Ji-Hoon Lee

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8 November 2017

Jaesang Kim

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8 November 2017

Won-Jae Lee

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8 November 2017

Jae Hong Seol

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8 November 2017

language of work or name

English

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publication date

18 February 2015

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8 November 2017

published in

Nature Communications

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8 November 2017

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8 November 2017

page(s)

6314

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salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines

8 November 2017

cites work

1 reference

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The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis

21 January 2018

1 reference

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Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway

21 January 2018

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Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila

21 January 2018

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The Drosophila Ste20 family kinase dMST functions as a tumor suppressor by restricting cell proliferation and promoting apoptosis

21 January 2018

1 reference

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila.

21 January 2018

1 reference

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The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP

21 January 2018

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Elucidation of a universal size-control mechanism in Drosophila and mammals

21 January 2018

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Human homologue of the Drosophila melanogaster lats tumour suppressor modulates CDC2 activity

21 January 2018

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Control of cell proliferation and apoptosis by mob as tumor suppressor, mats

21 January 2018

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YAP1 increases organ size and expands undifferentiated progenitor cells

21 January 2018

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Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control

21 January 2018

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The Hippo-Salvador pathway restrains hepatic oval cell proliferation, liver size, and liver tumorigenesis.

21 January 2018

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Hippo signaling is a potent in vivo growth and tumor suppressor pathway in the mammalian liver

21 January 2018

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Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma

21 January 2018

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Down-regulation of LATS1 and LATS2 mRNA expression by promoter hypermethylation and its association with biologically aggressive phenotype in human breast cancers

21 January 2018

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Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon

21 January 2018

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Expression of Yes-associated protein in common solid tumors

21 January 2018

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Identification and validation of oncogenes in liver cancer using an integrative oncogenomic approach

21 January 2018

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The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration

21 January 2018

1 reference

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Hippo signaling regulatesDrosophilaintestine stem cell proliferation through multiple pathways

21 January 2018

1 reference

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Delineation of a Fat tumor suppressor pathway

21 January 2018

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21 January 2018

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The HECT family of E3 ubiquitin ligases: multiple players in cancer development

21 January 2018

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The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2+-dependent plasma membrane localization

21 January 2018

1 reference

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Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition

21 January 2018

1 reference

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Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH is sufficient to promote tumorigenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functions

21 January 2018

1 reference

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Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

Yorkie: the final destination of Hippo signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

The predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradation

21 January 2018

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Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

21 January 2018

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Physiological functions of the HECT family of ubiquitin ligases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration

21 January 2018

1 reference

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Warts and Yorkie Mediate Intestinal Regeneration by Influencing Stem Cell Proliferation

21 January 2018

1 reference

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Bantam is essential for Drosophila intestinal stem cell proliferation in response to Hippo signaling.

21 January 2018

1 reference

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Hippo pathway-dependent and -independent roles of RASSF6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

The Fat and Warts signaling pathways: new insights into their regulation, mechanism and conservation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

KIBRA regulates Hippo signaling activity via interactions with large tumor suppressor kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

The WW domain protein Kibra acts upstream of Hippo in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

Kibra is a regulator of the Salvador/Warts/Hippo signaling network

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded

21 January 2018

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NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

21 January 2018

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Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

21 January 2018

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Lats2/Kpm is required for embryonic development, proliferation control and genomic integrity

21 January 2018

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A crucial role of WW45 in developing epithelial tissues in the mouse

21 January 2018

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Evidence that stem cells reside in the adult Drosophila midgut epithelium.

21 January 2018

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Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury.

21 January 2018

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Notch pathway: making sense of suppressor of hairless

21 January 2018

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Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut

21 January 2018

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Drosophila Nedd4 regulates endocytosis of notch and suppresses its ligand-independent activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

GFP reporters detect the activation of the Drosophila JAK/STAT pathway in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

The FLP recombinase of yeast catalyzes site-specific recombination in the Drosophila genome.

21 January 2018

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Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila.

21 January 2018

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Nedd4 controls animal growth by regulating IGF-1 signaling

21 January 2018

1 reference

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inferred from DOI database lookup

7 January 2021

based on heuristic

NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

inferred from DOI database lookup

7 January 2021

based on heuristic

Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS7314

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NCOMMS7314

1 reference

Dimensions Publication ID

8 November 2017

0 references

1001787049

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1 reference