Role of Neuro-Immunological Factors in the Pathophysiology of Mood Disorders: Implications for Novel Therapeutics for Treatment Resistant Depression (Q38966223)

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scientific article published on 28 September 2016

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English	Role of Neuro-Immunological Factors in the Pathophysiology of Mood Disorders: Implications for Novel Therapeutics for Treatment Resistant Depression	scientific article published on 28 September 2016

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scholarly article

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Europe PubMed Central

PubMed publication ID

8 September 2017

1 reference

Europe PubMed Central

Role of Neuro-Immunological Factors in the Pathophysiology of Mood Disorders: Implications for Novel Therapeutics for Treatment Resistant Depression (English)

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Anindya Bhattacharya

1

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

Wayne C Drevets

2

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

publication date

28 September 2016

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Europe PubMed Central

PubMed publication ID

8 September 2017

Current topics in behavioral neurosciences

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Europe PubMed Central

PubMed publication ID

8 September 2017

31

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

339-356

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R)

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Faster, better, stronger: towards new antidepressant therapeutic strategies

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Towards new mechanisms: an update on therapeutics for treatment-resistant major depressive disorder

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Lack of clinical therapeutic benefit of antidepressants is associated overall activation of the inflammatory system.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline 'predictors' and longitudinal 'targets'.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

An inflammatory biomarker as a differential predictor of outcome of depression treatment with escitalopram and nortriptyline

1 reference

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21 January 2018

Higher plasma interleukin-6 (IL-6) level is associated with SSRI- or SNRI-refractory depression

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Neuroscience, mental health and the immune system: overcoming the brain-mind-body trichotomy.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Integrating neuroimmune systems in the neurobiology of depression.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Imaging robust microglial activation after lipopolysaccharide administration in humans with PET.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Innate and adaptive immunity in the development of depression: An update on current knowledge and technological advances

1 reference

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21 January 2018

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

1 reference

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21 January 2018

Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress

1 reference

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21 January 2018

Anti-inflammatory Intervention in Depression--Reply

1 reference

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21 January 2018

Activation of the reward system boosts innate and adaptive immunity

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Revisiting the Mechanisms of CNS Immune Privilege

1 reference

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21 January 2018

Immune modulation of learning, memory, neural plasticity and neurogenesis

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Role of neuro-immunological factors in the pathophysiology of mood disorders

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Inflammation and neurological disease-related genes are differentially expressed in depressed patients with mood disorders and correlate with morphometric and functional imaging abnormalities

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Bipolar and major depressive disorder: neuroimaging the developmental-degenerative divide

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Genetics of bipolar disorder

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Unipolar depressive disorders have a common genotype

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Polygenic dissection of major depression clinical heterogeneity

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Immune system to brain signaling: neuropsychopharmacological implications.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Structural and functional features of central nervous system lymphatic vessels

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

How Do Meningeal Lymphatic Vessels Drain the CNS?

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Microglia: Dynamic Mediators of Synapse Development and Plasticity.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Glia: the many ways to modulate synaptic plasticity

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Microglial M1/M2 polarization and metabolic states

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

A polarizing question: do M1 and M2 microglia exist?

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Neuroinflammation and M2 microglia: the good, the bad, and the inflamed.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic neurotransmission?

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Microglia: scapegoat, saboteur, or something else?

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

The role of glial cells in synapse elimination

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Deficient neuron-microglia signaling results in impaired functional brain connectivity and social behavior.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Depression as a microglial disease.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Adaptive immunity affects learning behavior in mice

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Regulation of learning and memory by meningeal immunity: a key role for IL-4

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Febrile illness and pro-inflammatory cytokines are associated with lower neurodevelopmental scores in Bangladeshi infants living in poverty

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

T cell deficiency leads to cognitive dysfunction: implications for therapeutic vaccination for schizophrenia and other psychiatric conditions

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Immune cells contribute to the maintenance of neurogenesis and spatial learning abilities in adulthood

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Innate immunity to Toxoplasma gondii infection

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Autoreactive T cells promote post-traumatic healing in the central nervous system.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Myelin specific Th1 cells are necessary for post-traumatic protective autoimmunity

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Cytokine-induced sickness behavior.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Gene networks specific for innate immunity define post-traumatic stress disorder.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Serum proteomic profiles of depressive subtypes

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Targeting the inflammatory pathway as a therapeutic tool for major depression.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Inflamed moods: a review of the interactions between inflammation and mood disorders

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Neuroinflammation and comorbidity of pain and depression

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

A meta-analysis of cytokines in major depression

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

The role of the innate immune system in psychiatric disorders

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Cytokines and glucocorticoid receptor signaling. Relevance to major depression

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Elevation of cerebrospinal fluid interleukin-1ß in bipolar disorder

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

A review of the relationship between proinflammatory cytokines and major depressive disorder

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Inflammatory activation is associated with a reduced glucocorticoid receptor alpha/beta expression ratio in monocytes of inpatients with melancholic major depressive disorder.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Gene expression in major depressive disorder

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

A discriminating messenger RNA signature for bipolar disorder formed by an aberrant expression of inflammatory genes in monocytes.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Symptomatic treatment of interferon-α-induced depression in hepatitis C: a systematic review

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Cytokines and sickness behavior.

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Does cytokine-induced depression differ from idiopathic major depression in medically healthy individuals?

1 reference

https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Differences in depressive thoughts between major depressive disorder, IFN-alpha-induced depression, and depressive disorders among cancer patients

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21 January 2018

Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment

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https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Prophylactic antidepressant treatment of interferon-induced depression in chronic hepatitis C: a systematic review and meta-analysis

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21 January 2018

Neurobehavioral effects of interferon-α in patients with hepatitis-C: symptom dimensions and responsiveness to paroxetine

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https://api.crossref.org/works/10.1007%2F7854_2016_43

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Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial.

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Stability and transitions of depressive subtypes over a 2-year follow-up

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https://api.crossref.org/works/10.1007%2F7854_2016_43

21 January 2018

Clinical characteristics of inflammation-associated depression: Monocyte gene expression is age-related in major depressive disorder

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21 January 2018

The mononuclear phagocyte system and its cytokine inflammatory networks in schizophrenia and bipolar disorder

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21 January 2018

Neuroimmune mechanisms of depression

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21 January 2018

From inflammation to sickness and depression: when the immune system subjugates the brain

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21 January 2018

TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting

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21 January 2018

Neurobehavioral alterations in mice with a targeted deletion of the tumor necrosis factor-alpha gene: implications for emotional behavior.

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21 January 2018

Chronic administration of infliximab (TNF-α inhibitor) decreases depression and anxiety-like behaviour in rat model of chronic mild stress.

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21 January 2018

Antidepressant effects of TNF-α blockade in an animal model of depression

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21 January 2018

A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers

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21 January 2018

Targeting classical IL-6 signalling or IL-6 trans-signalling in depression?

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21 January 2018

A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality

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21 January 2018

Interleukin-1beta serum levels is increased in antidepressant-free elderly depressed patients.

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21 January 2018

Targeting IL-1 in depression

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IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress

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21 January 2018

NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation

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Interleukin 1 beta enhances conditioned fear memory in rats: possible involvement of glucocorticoids

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Psychological Stress Activates the Inflammasome via Release of Adenosine Triphosphate and Stimulation of the Purinergic Type 2X7 Receptor.

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21 January 2018

Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors

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Altered cytokine production in mice lacking P2X(7) receptors

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Non-synonymous single nucleotide polymorphisms in the P2X receptor genes: association with diseases, impact on receptor functions and potential use as diagnosis biomarkers

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Insights into the Molecular Mechanisms Underlying Mammalian P2X7 Receptor Functions and Contributions in Diseases, Revealed by Structural Modeling and Single Nucleotide Polymorphisms

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Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion

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Lack of association of P2RX7 gene rs2230912 polymorphism with mood disorders: a meta-analysis

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Increased excitotoxicity and neuroinflammatory markers in postmortem frontal cortex from bipolar disorder patients

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21 January 2018

Role of P2X7 Receptor in an Animal Model of Mania Induced by D-Amphetamine.

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Pharmacological characterization of a novel centrally permeable P2X7 receptor antagonist: JNJ-47965567.

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Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432.

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Identifiers

10.1007/7854_2016_43

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

8 September 2017

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