Alternative splicing: an emerging topic in molecular and clinical oncology (Q36774636)

16 August 2017

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title

Alternative splicing: an emerging topic in molecular and clinical oncology (English)

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alternative mRNA splicing, via spliceosome

16 August 2017

main subject

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Ruben Pio

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Alfonso Calvo

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María J Pajares

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16 August 2017

Teresa Ezponda

series ordinal

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16 August 2017

Raúl Catena

series ordinal

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16 August 2017

Luis M Montuenga

series ordinal

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16 August 2017

publication date

1 April 2007

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Lancet Oncology Commission

16 August 2017

published in

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16 August 2017

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16 August 2017

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16 August 2017

page(s)

349-357

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A genomic view of alternative splicing

16 August 2017

cites work

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Profiling alternative splicing on fiber-optic arrays

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Examples of the complex architecture of the human transcriptome revealed by RACE and high-density tiling arrays

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Detection of alternatively spliced transcripts in leukemia cell lines by minisequencing on microarrays

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Regulation of apoptosis by alternative pre-mRNA splicing

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Alternative splicing: new insights from global analyses

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Mutations affecting mRNA splicing are the most common molecular defects in patients with neurofibromatosis type 1.

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Building specificity with nonspecific RNA-binding proteins

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Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis

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7 January 2021

Relative amounts of antagonistic splicing factors, hnRNP A1 and ASF/SF2, change during neoplastic lung growth: implications for pre-mRNA processing

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De novo ceramide regulates the alternative splicing of caspase 9 and Bcl-x in A549 lung adenocarcinoma cells. Dependence on protein phosphatase-1.

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7 January 2021

Differential regulation of survivin expression and apoptosis by vitamin D3 compounds in two isogenic MCF-7 breast cancer cell sublines

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7 January 2021

An alternatively spliced survivin variant is positively regulated by p53 and sensitizes leukemia cells to chemotherapy

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7 January 2021

Expression of different survivin variants in gastric carcinomas: first clues to a role of survivin-2B in tumour progression

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7 January 2021

An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis.

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Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

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7 January 2021

Quantitation of telomerase components and hTERT mRNA splicing patterns in immortal human cells

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7 January 2021

Telomerase downregulation induced by the G-quadruplex ligand 12459 in A549 cells is mediated by hTERT RNA alternative splicing.

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7 January 2021

The biology of VEGF and its receptors

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7 January 2021

Isoforms of vascular endothelial growth factor act in a coordinate fashion To recruit and expand tumor vasculature.

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7 January 2021

The 121 amino acid isoform of vascular endothelial growth factor is more strongly tumorigenic than other splice variants in vivo

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements

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7 January 2021

Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

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7 January 2021

Phase III study of gemcitabine and cisplatin with or without aprinocarsen, a protein kinase C-alpha antisense oligonucleotide, in patients with advanced-stage non-small-cell lung cancer

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7 January 2021

Bcl-2 antisense (oblimersen sodium) plus dacarbazine in patients with advanced melanoma: the Oblimersen Melanoma Study Group

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7 January 2021

Restoration of hemoglobin A synthesis in erythroid cells from peripheral blood of thalassemic patients

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7 January 2021

Systemic delivery of morpholino oligonucleotide restores dystrophin expression bodywide and improves dystrophic pathology

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7 January 2021

Spliceosome-mediated RNA trans-splicing as a tool for gene therapy

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Efficient in vivo gene expression by trans-splicing adeno-associated viral vectors

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7 January 2021

Safety, biodistribution, pharmacokinetics, and immunogenicity of 99mTc-labeled humanized monoclonal antibody BIWA 4 (bivatuzumab) in patients with squamous cell carcinoma of the head and neck

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7 January 2021

Tumor-targeting properties of novel antibodies specific to the large isoform of tenascin-C.

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7 January 2021

Manipulation of alternative splicing by a newly developed inhibitor of Clks

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7 January 2021

Targeting the RNA splicing machinery as a novel treatment strategy for pancreatic carcinoma

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7 January 2021

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Identifiers

DOI

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16 August 2017

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