Mechanism of aromatic amine carcinogen bypass by the Y-family polymerase, Dpo4. (Q36676542)

15 August 2017

Mechanism of aromatic amine carcinogen bypass by the Y-family polymerase, Dpo4. (English)

1 reference

15 August 2017

Alfonso Brenlla

1 reference

15 August 2017

David Rueda

series ordinal

1 reference

15 August 2017

Louis J Romano

series ordinal

1 reference

15 August 2017

language of work or name

English

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publication date

19 October 2015

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15 August 2017

Nucleic Acids Research

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15 August 2017

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15 August 2017

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15 August 2017

9918-9927

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Creative Commons Attribution 4.0 International

15 August 2017

start time

5 October 2016

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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Structural Mechanism of Replication Stalling on a Bulky Amino-Polycyclic Aromatic Hydrocarbon DNA Adduct by a Y Family DNA Polymerase

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The Y-Family DNA Polymerase Dpo4 Uses a Template Slippage Mechanism To Create Single-Base Deletions

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Mechanism of replication blocking and bypass of Y-family polymerase by bulky acetylaminofluorene DNA adducts

30 September 2017

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Mechanism of error-free and semitargeted mutagenic bypass of an aromatic amine lesion by Y-family polymerase Dpo4

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30 September 2017

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A structural gap in Dpo4 supports mutagenic bypass of a major benzo[a]pyrene dG adduct in DNA through template misalignment

30 September 2017

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A new anti conformation for N-(deoxyguanosin-8-yl)-2-acetylaminofluorene (AAF-dG) allows Watson-Crick pairing in the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4).

30 September 2017

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Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion

30 September 2017

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DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine.

30 September 2017

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Cytochrome P450 activation of arylamines and heterocyclic amines

30 September 2017

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Crystal structures of 2-acetylaminofluorene and 2-aminofluorene in complex with T7 DNA polymerase reveal mechanisms of mutagenesis

30 September 2017

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Environmental and chemical carcinogenesis

30 September 2017

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Chemical-induced DNA damage and human cancer risk

30 September 2017

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Crystal structure of a benzo[a]pyrene diol epoxide adduct in a ternary complex with a DNA polymerase

30 September 2017

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Damage repair DNA polymerases Y.

30 September 2017

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Arylamine exposures and bladder cancer risk

30 September 2017

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Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4): an archaeal DinB-like DNA polymerase with lesion-bypass properties akin to eukaryotic poleta

30 September 2017

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Mechanisms of accurate translesion synthesis by human DNA polymerase eta

30 September 2017

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Specificity of DNA lesion bypass by the yeast DNA polymerase eta.

30 September 2017

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hRAD30 mutations in the variant form of xeroderma pigmentosum

30 September 2017

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The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta

30 September 2017

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Interaction of Escherichia coli DNA polymerase I (Klenow fragment) with primer-templates containing N-acetyl-2-aminofluorene or N-2-aminofluorene adducts in the active site

30 September 2017

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Epidemiology of cancer from exposure to arylamines

30 September 2017

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Formation and persistence of arylamine DNA adducts in vivo

30 September 2017

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Carcinogen-induced frameshift mutagenesis in repetitive sequences

30 September 2017

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Mechanistic studies of the bypass of a bulky single-base lesion catalyzed by a Y-family DNA polymerase

30 September 2017

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8-(N-2-Fluorenylacetamido) guanosine, an Arylamidation Reaction Product of Guanosine and the Carcinogen N-Acetoxy-N-2-fluorenylacetamide in Neutral Solution*

28 June 2018

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Association between DNA strand breaks and specific DNA adducts in murine hepatocytes following in vivo and in vitro exposure to N-hydroxy-2-acetylaminofluorene and N-acetoxy-2-acetylaminofluorene

28 June 2018

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Mutagenesis by single site-specific arylamine-DNA adducts. Induction of mutations at multiple sites.

28 June 2018

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Mutations induced by aminofluorene-DNA adducts during replication in human cells

28 June 2018

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Mutagenesis by site-specific arylamine adducts in plasmid DNA: enhancing replication of the adducted strand alters mutation frequency.

28 June 2018

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Fifty years of research on N-acetyl-2-aminofluorene, one of the most versatile compounds in experimental cancer research.

28 June 2018

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Nucleotide selectivity opposite a benzo[a]pyrene-derived N2-dG adduct in a Y-family DNA polymerase: a 5'-slippage mechanism

28 June 2018

1 reference

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Mutagenic events in Escherichia coli and mammalian cells generated in response to acetylaminofluorene-derived DNA adducts positioned in the Nar I restriction enzyme site

5 September 2018

1 reference

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Translesional synthesis past acetylaminofluorene-derived DNA adducts catalyzed by human DNA polymerase kappa and Escherichia coli DNA polymerase IV.

5 September 2018

1 reference

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Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli. Strain specificity and mutation-prone sequences.

5 September 2018

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Hot spots of frameshift mutations induced by the ultimate carcinogen N- acetoxy-N-2-acetylaminofluorene

5 September 2018

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Crossref

https://api.crossref.org/works/10.1093%2FNAR%2FGKV1067

Structural characterization of an N-acetyl-2-aminofluorene (AAF) modified DNA oligomer by NMR, energy minimization, and molecular dynamics

21 January 2018

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12 December 2020

Mutagenesis at a site-specifically modified NarI sequence by acetylated and deacetylated aminofluorene adducts

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12 December 2020

2–Aminofluorene modified DNA duplex exists in two interchangeable conformations

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12 December 2020

Mechanisms of frameshift mutations: insight from aromatic amines

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12 December 2020

Nuclear magnetic resonance solution structures of covalent aromatic amine-DNA adducts and their mutagenic relevance

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12 December 2020

Mutagenic specificity of (acetylamino)fluorene-derived DNA adducts in mammalian cells

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12 December 2020

Translesion synthesis across polycyclic aromatic hydrocarbon diol epoxide adducts of deoxyadenosine by Sulfolobus solfataricus DNA polymerase Dpo4

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12 December 2020

Chemical-induced DNA damage and human cancer risk

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKV1067

1 reference

15 August 2017

1 reference

15 August 2017

PubMed publication ID

26481355

1 reference