A Basis for Rapid Clearance of Circulating Ring-Stage Malaria Parasites by the Spiroindolone KAE609. (Q36365291)

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18 February 2020

title

A Basis for Rapid Clearance of Circulating Ring-Stage Malaria Parasites by the Spiroindolone KAE609 (English)

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18 February 2020

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Bruce Malcolm Russell

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18 February 2020

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18 February 2020

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18 February 2020

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18 February 2020

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18 February 2020

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18 February 2020

Laurent Renia

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18 February 2020

Rou Zhang

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18 February 2020

Rossarin Suwanarusk

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18 February 2020

Brian M Cooke

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18 February 2020

Kevin Shyong Wei Tan

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18 February 2020

language of work or name

English

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publication date

1 July 2015

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Journal of Infectious Diseases

18 February 2020

published in

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18 February 2020

volume

213

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18 February 2020

issue

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18 February 2020

page(s)

100-104

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(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.

18 February 2020

cites work

1 reference

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Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum

30 September 2017

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Plasmodium vivax: restricted tropism and rapid remodeling of CD71-positive reticulocytes

30 September 2017

1 reference

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Spiroindolone KAE609 for falciparum and vivax malaria

30 September 2017

1 reference

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The cellular and molecular rheology of malaria

30 September 2017

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A novel live-dead staining methodology to study malaria parasite viability.

30 September 2017

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Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials

30 September 2017

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Quantitative assessment of sensing and sequestration of spherocytic erythrocytes by the human spleen

30 September 2017

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Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study

30 September 2017

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Host cell deformability is linked to transmission in the human malaria parasite Plasmodium falciparum.

30 September 2017

1 reference

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Mechanisms and significance of eryptosis, the suicidal death of erythrocytes

30 September 2017

1 reference

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A programmed cell death pathway in the malaria parasite Plasmodium falciparum has general features of mammalian apoptosis but is mediated by clan CA cysteine proteases.

30 September 2017

1 reference

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Spiroindolones, a potent compound class for the treatment of malaria

30 September 2017

1 reference

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High deformability of Plasmodium vivax-infected red blood cells under microfluidic conditions

30 September 2017

1 reference

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The deformability of red blood cells parasitized by Plasmodium falciparum and P. vivax

30 September 2017

1 reference

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Rheologic properties of senescent erythrocytes: loss of surface area and volume with red blood cell age

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26136472

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/INFDIS/JIV358

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18 February 2020

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18 February 2020

PubMed publication ID

26136472

1 reference

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