Low folding cooperativity of HP35 revealed by single-molecule force spectroscopy and molecular dynamics simulation (Q35895128)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22768951%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Low folding cooperativity of HP35 revealed by single-molecule force spectroscopy and molecular dynamics simulation (English)

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7 February 2020

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7 February 2020

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7 February 2020

Chunmei Lv

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7 February 2020

Meng Qin

series ordinal

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7 February 2020

Dawei Zou

series ordinal

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7 February 2020

Wei Wang

series ordinal

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7 February 2020

language of work or name

English

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publication date

1 April 2012

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7 February 2020

number of pages

1 reference

inferred from page(s)

published in

Biophysical Journal

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7 February 2020

volume

102

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7 February 2020

issue

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7 February 2020

page(s)

1944-1951

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One β hairpin follows the other: exploring refolding pathways and kinetics of the transmembrane β-barrel protein OmpG.

7 February 2020

cites work

1 reference

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How robust are protein folding simulations with respect to force field parameterization?

27 July 2018

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Dynamics of the folded and unfolded villin headpiece (HP35) measured with ultrafast 2D IR vibrational echo spectroscopy

27 July 2018

1 reference

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Naturally Occurring Osmolytes Modulate the Nanomechanical Properties of Polycystic Kidney Disease Domains

27 July 2018

1 reference

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Fast and forceful refolding of stretched alpha-helical solenoid proteins

27 July 2018

1 reference

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The folding cooperativity of a protein is controlled by its chain topology

27 July 2018

1 reference

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Phi-value analysis for ultrafast folding proteins by NMR relaxation dispersion.

27 July 2018

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Detection of a transient intermediate in a rapid protein folding process by solid-state nuclear magnetic resonance

27 July 2018

1 reference

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Refolding dynamics of stretched biopolymers upon force quench.

27 July 2018

1 reference

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Native like structure in the unfolded state of the villin headpiece helical subdomain, an ultrafast folding protein

27 July 2018

1 reference

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Direct observation of an ensemble of stable collapsed states in the mechanical folding of ubiquitin

27 July 2018

1 reference

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Osmolyte-induced separation of the mechanical folding phases of ubiquitin

27 July 2018

1 reference

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Ligand-dependent equilibrium fluctuations of single calmodulin molecules

27 July 2018

1 reference

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The effect of temperature on mechanical resistance of the native and intermediate states of I27.

27 July 2018

1 reference

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Stabilization provided by neighboring strands is critical for the mechanical stability of proteins.

27 July 2018

1 reference

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Single-molecule studies of protein folding.

27 July 2018

1 reference

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Revealing the bifurcation in the unfolding pathways of GFP by using single-molecule experiments and simulations

27 July 2018

1 reference

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Single-molecule experiments in vitro and in silico

27 July 2018

1 reference

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Folding free-energy landscape of villin headpiece subdomain from molecular dynamics simulations

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Conformational dynamics and ensembles in protein folding

27 July 2018

1 reference

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Anisotropic deformation response of single protein molecules.

27 July 2018

1 reference

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Protein misfolding, functional amyloid, and human disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Scalable molecular dynamics with NAMD

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Intrinsically unstructured proteins and their functions

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

The folding pathway of a fast-folding immunoglobulin domain revealed by single-molecule mechanical experiments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Exploring the energy landscape of GFP by single-molecule mechanical experiments

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Solution structures of the C-terminal headpiece subdomains of human villin and advillin, evaluation of headpiece F-actin-binding requirements

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

SWISS-MODEL: An automated protein homology-modeling server

27 July 2018

1 reference

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Experimental tests of villin subdomain folding simulations

27 July 2018

1 reference

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Is there a unifying mechanism for protein folding?

27 July 2018

1 reference

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Multiple conformations of PEVK proteins detected by single-molecule techniques

27 July 2018

1 reference

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The key event in force-induced unfolding of Titin's immunoglobulin domains

27 July 2018

1 reference

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Solid-state synthesis and mechanical unfolding of polymers of T4 lysozyme

27 July 2018

1 reference

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Strength of a weak bond connecting flexible polymer chains

27 July 2018

1 reference

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Pathways to a protein folding intermediate observed in a 1-microsecond simulation in aqueous solution

27 July 2018

1 reference

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

27 July 2018

1 reference

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From Levinthal to pathways to funnels

27 July 2018

1 reference

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Entropic elasticity of lambda-phage DNA

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Mechanically unfolding protein L using a laser-feedback-controlled cantilever

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Making connections between ultrafast protein folding kinetics and molecular dynamics simulations

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Force and function: probing proteins with AFM-based force spectroscopy.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Probing the folding transition state structure of the villin headpiece subdomain via side chain and backbone mutagenesis.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Engineered elastomeric proteins with dual elasticity can be controlled by a molecular regulator

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Mechanical unfoldons as building blocks of maltose-binding protein

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

How do chemical denaturants affect the mechanical folding and unfolding of proteins?

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Direct observation of active protein folding using lock-in force spectroscopy

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Polyprotein of GB1 is an ideal artificial elastomeric protein.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Denatured-state ensemble and the early-stage folding of the G29A mutant of the B-domain of protein A.

24 September 2018

1 reference

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Nanospring behaviour of ankyrin repeats.

24 September 2018

1 reference

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Nonmechanical protein can have significant mechanical stability.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Ultra-fast barrier-limited folding in the peripheral subunit-binding domain family

24 September 2018

1 reference

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Mechanical unfolding of TNfn3: the unfolding pathway of a fnIII domain probed by protein engineering, AFM and MD simulation.

24 September 2018

1 reference

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Mechanically unfolding the small, topologically simple protein L.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Mechanical unfolding intermediates observed by single-molecule force spectroscopy in a fibronectin type III module.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Force-clamp spectroscopy monitors the folding trajectory of a single protein

24 September 2018

1 reference

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Can non-mechanical proteins withstand force? Stretching barnase by atomic force microscopy and molecular dynamics simulation.

24 September 2018

1 reference

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Preorganized secondary structure as an important determinant of fast protein folding

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Atomic force microscopy reveals the mechanical design of a modular protein.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Unfolding proteins by external forces and temperature: the importance of topology and energetics

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Mechanical and chemical unfolding of a single protein: a comparison

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

A “Force Buffer” Protecting Immunoglobulin Titin

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3328709

Protein Folding Kinetics Under Force from Molecular Simulation

6 December 2018

1 reference

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Reversible unfolding of individual titin immunoglobulin domains by AFM

6 December 2018

1 reference

12 December 2020

Temperature softening of a protein in single-molecule experiments

1 reference

12 December 2020

NMR Characterization of a Peptide Model Provides Evidence for Significant Structure in the Unfolded State of the Villin Headpiece Helical Subdomain†

1 reference

12 December 2020

Simulated unfolded-state ensemble and the experimental NMR structures of villin headpiece yield similar wide-angle solution X-ray scattering profiles

1 reference

12 December 2020

Surprising simplicity in the single-molecule folding mechanics of proteins

1 reference

12 December 2020

Kinetic partitioning mechanism governs the folding of the third FnIII domain of tenascin-C: evidence at the single-molecule level

1 reference

12 December 2020

Experimental free energy surface reconstruction from single-molecule force spectroscopy using Jarzynski's equality

1 reference

12 December 2020

Single protein misfolding events captured by atomic force microscopy

1 reference

12 December 2020

10.1016/J.BPJ.2012.03.028

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22768951%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22768951%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

22768951

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22768951%20AND%20SRC:MED&resulttype=core&format=json