Cytoskeletal regulation: rich in lipids (Q35887301)

10 August 2017

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title

Cytoskeletal regulation: rich in lipids (English)

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10 August 2017

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Paul A Janmey

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10 August 2017

Uno Lindberg

series ordinal

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10 August 2017

publication date

1 August 2004

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Nature Reviews Molecular Cell Biology

10 August 2017

published in

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10 August 2017

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10 August 2017

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10 August 2017

page(s)

658-666

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Intercellular adhesion, signalling and the cytoskeleton

10 August 2017

cites work

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Interplay between TCR signalling and actin cytoskeleton dynamics.

21 January 2018

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Role of the cytoskeleton in signaling networks

21 January 2018

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Structural properties of lipid-binding sites in cytoskeletal proteins

21 January 2018

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Phosphoinositide regulation of the actin cytoskeleton

21 January 2018

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Role of phosphatidylinositol(4,5)bisphosphate organization in membrane transport by the Unc104 kinesin motor

21 January 2018

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Dynamin 2 binds gamma-tubulin and participates in centrosome cohesion

21 January 2018

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Regulating actin dynamics at membranes: a focus on dynamin

21 January 2018

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A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells

21 January 2018

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Identification of the Binding Site for Acidic Phospholipids on the PH Domain of Dynamin: Implications for Stimulation of GTPase Activity

21 January 2018

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Phosphatidylinositol 4,5-bisphosphate induces actin stress-fiber formation and inhibits membrane ruffling in CV1 cells

21 January 2018

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Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3.

21 January 2018

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Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filaments

21 January 2018

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Cell permeant polyphosphoinositide-binding peptides that block cell motility and actin assembly

21 January 2018

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Phosphatidylinositol 4,5-bisphosphate functions as a second messenger that regulates cytoskeleton-plasma membrane adhesion

21 January 2018

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Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42.

21 January 2018

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Regulation of phosphatidylinositol 4,5-bisphosphate levels and its roles in cytoskeletal re-organization and malignant transformation

21 January 2018

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Conversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphology

21 January 2018

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The deficiency of PIP2 5-phosphatase in Lowe syndrome affects actin polymerization

21 January 2018

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Centaurin-alpha1 is an in vivo phosphatidylinositol 3,4,5-trisphosphate-dependent GTPase-activating protein for ARF6 that is involved in actin cytoskeleton organization

21 January 2018

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Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nck, WIP, and Grb2

21 January 2018

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The complex and intriguing lives of PIP2 with ion channels and transporters

21 January 2018

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A new phosphatidylinositol 4,5-bisphosphate-binding site located in the C2 domain of protein kinase Calpha.

21 January 2018

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Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes

21 January 2018

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Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin

21 January 2018

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Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin

21 January 2018

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Corequirement of specific phosphoinositides and small GTP-binding protein Cdc42 in inducing actin assembly in Xenopus egg extracts

21 January 2018

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Dibasic amino acid residues at the carboxy-terminal end of kinase homology domain participate in the plasma membrane localization and function of phosphatidylinositol 5-kinase gamma

21 January 2018

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Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate

21 January 2018

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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

21 January 2018

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Visualization of spatially and temporally regulated N-WASP activity during cytoskeletal reorganization in living cells

21 January 2018

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Polymer motors: pushing out the front and pulling up the back

21 January 2018

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PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia

21 January 2018

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Leading the way: Directional sensing through phosphatidylinositol 3-kinase and other signaling pathways.

21 January 2018

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PIP3, PIP2, and cell movement--similar messages, different meanings?

21 January 2018

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Phosphoinositide kinases as enzymes that produce versatile signaling lipids, phosphoinositides

21 January 2018

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Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling

21 January 2018

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Phosphatidylinositol Phosphate Kinases Put PI4,5P 2 in Its Place

21 January 2018

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ARNO and ARF6 Regulate Axonal Elongation and Branching through Downstream Activation of Phosphatidylinositol 4-Phosphate 5-Kinase α

21 January 2018

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Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions

21 January 2018

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Inhibition of phosphatidylinositol-4-phosphate 5-kinase Ialpha impairs localized actin remodeling and suppresses phagocytosis.

21 January 2018

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Solution structure of the pleckstrin homology domain of Drosophila beta-spectrin

21 January 2018

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Pleckstrin homology domains and the cytoskeleton

21 January 2018

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Mutagenesis of the phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding site in the NH(2)-terminal domain of ezrin correlates with its altered cellular distribution

21 January 2018

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Membrane targeting of protein tyrosine phosphatase PTPL1 through its FERM domain via binding to phosphatidylinositol 4,5-biphosphate.

21 January 2018

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The interaction of titin and alpha-actinin is controlled by a phospholipid-regulated intramolecular pseudoligand mechanism

21 January 2018

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Requirement of phosphatidylinositol 4,5-bisphosphate for alpha-actinin function

21 January 2018

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A new phospholipase C delta 4 is induced at S-phase of the cell cycle and appears in the nucleus

21 January 2018

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Phosphoinositide binding inhibits alpha-actinin bundling activity.

21 January 2018

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Phosphoinositides differentially regulate alpha-actinin flexibility and function

21 January 2018

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Regulation of vinculin binding to talin and actin by phosphatidyl-inositol-4-5-bisphosphate

21 January 2018

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Polyphosphoinositides inhibit the interaction of vinculin with actin filaments

21 January 2018

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Talin: an emerging focal point of adhesion dynamics

21 January 2018

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Dissecting the gelsolin-polyphosphoinositide interaction and engineering of a polyphosphoinositide-sensitive gelsolin C-terminal half protein.

21 January 2018

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Association of Villin with Phosphatidylinositol 4,5-Bisphosphate Regulates the Actin Cytoskeleton

21 January 2018

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Mapping the functional surface of domain 2 in the gelsolin superfamily

21 January 2018

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The phosphoinositides exist in multiple metabolic pools in rabbit platelets

21 January 2018

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Spatial sensing in fibroblasts mediated by 3' phosphoinositides

21 January 2018

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Phosphoinositides and phosphoinositide-utilizing enzymes in detergent-insoluble lipid domains

21 January 2018

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Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

21 January 2018

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Dynamics of phosphatidylinositol 4,5-bisphosphate in actin-rich structures

21 January 2018

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Eukaryotic chemotaxis: distinctions between directional sensing and polarization

21 January 2018

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Agonist-induced PIP(2) hydrolysis inhibits cortical actin dynamics: regulation at a global but not at a micrometer scale

21 January 2018

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Mechanical constraint imposed on plasma membrane through transverse phospholipid imbalance induces reversible actin polymerization via phosphoinositide 3-kinase activation.

21 January 2018

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PIP(2) and proteins: interactions, organization, and information flow

21 January 2018

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Lateral sequestration of phosphatidylinositol 4,5-bisphosphate by the basic effector domain of myristoylated alanine-rich C kinase substrate is due to nonspecific electrostatic interactions

21 January 2018

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Binding of peptides with basic and aromatic residues to bilayer membranes: phenylalanine in the myristoylated alanine-rich C kinase substrate effector domain penetrates into the hydrophobic core of the bilayer

21 January 2018

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The distribution of polyphosphoinositides in lipid films.

21 January 2018

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Molecular dynamics study of a gelsolin-derived peptide binding to a lipid bilayer containing phosphatidylinositol 4,5-bisphosphate.

21 January 2018

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The crystal structure of plasma gelsolin: implications for actin severing, capping, and nucleation

21 January 2018

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Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly

21 January 2018

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High Affinity Binding of Inositol Phosphates and Phosphoinositides to the Pleckstrin Homology Domain of RAC/Protein Kinase B and Their Influence on Kinase Activity

21 January 2018

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The profilin--actin complex: further characterization of profilin and studies on the stability of the complex

21 January 2018

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Diacylglycerol in large alpha-actinin/actin complexes and in the cytoskeleton of activated platelets

31 March 2020

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Regulation of the association of membrane skeletal protein 4.1 with glycophorin by a polyphosphoinositide

31 March 2020

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Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

31 March 2020

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Phosphatidylinositol 4,5-bisphosphate modifies tubulin participation in phospholipase Cbeta1 signaling.

31 March 2020

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Mechanical effects of neurofilament cross-bridges. Modulation by phosphorylation, lipids, and interactions with F-actin

31 March 2020

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N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases

31 March 2020

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Massive actin polymerization induced by phosphatidylinositol-4-phosphate 5-kinase in vivo

31 March 2020

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Phosphatidylinositol 4,5-bisphosphate regulates adipocyte actin dynamics and GLUT4 vesicle recycling

31 March 2020

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Separation of insulin signaling into distinct GLUT4 translocation and activation steps

31 March 2020

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Phosphoinositide recognition domains

31 March 2020

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Structure of the binding site for inositol phosphates in a PH domain

31 March 2020

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Identification of a phosphatidylinositol 4,5-bisphosphate-binding site in chicken skeletal muscle alpha-actinin

31 March 2020

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Structural changes in profilin accompany its binding to phosphatidylinositol 4,5‐bisphosphate

31 March 2020

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Spectroscopic studies of a phosphoinositide-binding peptide from gelsolin: behavior in solutions of mixed solvent and anionic micelles

31 March 2020

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Inositol lipid turnover and compartmentation in canine trachealis smooth muscle

31 March 2020

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Characterization of structural and functional phosphoinositide domains in human erythrocyte membranes

31 March 2020

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Structure of molecular aggregates of 1-(3-sn-phosphatidyl)-l-myo-inositol 3,4-bis(phosphate) in water

31 March 2020

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The structure of divalent cation-induced aggregates of PIP2 and their alteration by gelsolin and tau

31 March 2020

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Electrostatic sequestration of PIP2 on phospholipid membranes by basic/aromatic regions of proteins

31 March 2020

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Domain formation in phosphatidylinositol monophosphate/phosphatidylcholine mixed vesicles

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRM1434

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10 August 2017

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