Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells (Q35752316)

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scientific article published on 21 August 2015

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English	Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells	scientific article published on 21 August 2015

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26295810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Inhibiting the Recruitment of PLCγ1 to Kaposi's Sarcoma Herpesvirus K15 Protein Reduces the Invasiveness and Angiogenesis of Infected Endothelial Cells (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26295810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

0 references

Kaposi's sarcoma

1 reference

based on heuristic

inferred from title

neoplastic invasiveness

1 reference

based on heuristic

inferred from title

Magdalena Weidner-Glunde

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26295810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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Silvia Gramolelli

1

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22 February 2020

Bizunesh Abere

3

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22 February 2020

Abel Viejo-Borbolla

4

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22 February 2020

Kiran Bala

5

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22 February 2020

Jessica Rückert

6

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22 February 2020

Elisabeth Kremmer

7

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22 February 2020

Thomas F Schulz

8

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22 February 2020

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21 August 2015

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22 February 2020

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22 February 2020

11

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22 February 2020

8

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22 February 2020

e1005105

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22 February 2020

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Creative Commons Attribution 4.0 International

21 August 2015

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April 2022 Public Data File from Crossref

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describes a project that uses

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Generation of high-titre virus stocks using BrK.219, a B-cell line infected stably with recombinant Kaposi's sarcoma-associated herpesvirus

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Activation of NF-κB by the Kaposi's sarcoma-associated herpesvirus K15 protein involves recruitment of the NF-κB-inducing kinase, IκB kinases, and phosphorylation of p65.

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The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells

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Kaposi Sarcoma Pathogenesis: A Triad of Viral Infection, Oncogenesis and Chronic Inflammation.

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2 October 2017

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation

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2 October 2017

Kaposi's sarcoma herpesvirus K15 protein contributes to virus-induced angiogenesis by recruiting PLCγ1 and activating NFAT1-dependent RCAN1 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546648

2 October 2017

Superbinder SH2 domains act as antagonists of cell signaling

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The language of SH2 domain interactions defines phosphotyrosine-mediated signal transduction

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2 October 2017

Deletion of Kaposi's sarcoma-associated herpesvirus FLICE inhibitory protein, vFLIP, from the viral genome compromises the activation of STAT1-responsive cellular genes and spindle cell formation in endothelial cells

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2 October 2017

SH2 Domains Recognize Contextual Peptide Sequence Information to Determine Selectivity

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Cell signaling in space and time: where proteins come together and when they're apart

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Synthetic gene regulation circuits for control of cell expansion

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2 October 2017

Identification and functional characterization of a spliced rhesus rhadinovirus gene with homology to the K15 gene of Kaposi's sarcoma-associated herpesvirus

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Phospholipase Cgamma1 is required for metastasis development and progression

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The M type K15 protein of Kaposi's sarcoma-associated herpesvirus regulates microRNA expression via its SH2-binding motif to induce cell migration and invasion

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The PIX-GIT complex: a G protein signaling cassette in control of cell shape

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2 October 2017

Kaposi's sarcoma: a model of both malignancy and chronic inflammation

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2 October 2017

Role of phospholipase Cgamma1 in cell spreading requires association with a beta-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1.

1 reference

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2 October 2017

Functional characterization of the M-type K15-encoded membrane protein of Kaposi's sarcoma-associated herpesvirus

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4546648

2 October 2017

Kaposi's sarcoma-associated herpesvirus infection promotes invasion of primary human umbilical vein endothelial cells by inducing matrix metalloproteinases

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Intramolecular regulation of phospholipase C-gamma1 by its C-terminal Src homology 2 domain

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Activation of mitogen-activated protein kinase and NF-kappaB pathways by a Kaposi's sarcoma-associated herpesvirus K15 membrane protein

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12 December 2020

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10.1371/JOURNAL.PPAT.1005105

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22 February 2020

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22 February 2020

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22 February 2020

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