Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice. (Q34718783)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

title

Δ40 Isoform of p53 controls β-cell proliferation and glucose homeostasis in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Dan Kawamori

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Chong Wee Liew

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Bernhard Maier

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Jiang Hu

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Susanna R Keller

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Raghavendra G Mirmira

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Heidi Scrable

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Rohit N Kulkarni

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

language of work or name

English

0 references

publication date

25 February 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

page(s)

1210-1222

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

23 January 2020

start time

27 August 2021

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

Cyclin D2 is essential for the compensatory beta-cell hyperplastic response to insulin resistance in rodents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Regenerating pancreatic beta-cells: plasticity of adult pancreatic cells and the feasibility of in-vivo neogenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Absence of p53-dependent apoptosis combined with nonhomologous end-joining deficiency leads to a severe diabetic phenotype in mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Polycomb protein Ezh2 regulates pancreatic beta-cell Ink4a/Arf expression and regeneration in diabetes mellitus.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Survey of the human pancreatic beta-cell G1/S proteome reveals a potential therapeutic role for cdk-6 and cyclin D1 in enhancing human beta-cell replication and function in vivo

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Differential expression of cell cycle proteins during ageing of pancreatic islet cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Growth factor control of pancreatic islet regeneration and function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Regenerative capacity of neural precursors in the adult mammalian brain is under the control of p53.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

p53 and its isoforms in cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

The emerging role of FOXO transcription factors in pancreatic beta cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Molecular control of cell cycle progression in the pancreatic beta-cell

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Diabetes mellitus in the elderly: insulin resistance and/or impaired insulin secretion?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

IGF-1 increases laminin, cyclin D1, and p21Cip1 expression in glomerular mesangial cells: an investigation of the intracellular signaling pathway and cell-cycle progression.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

FOXO transcription factors at the interface between longevity and tumor suppression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

p53 isoforms can regulate p53 transcriptional activity.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

The p53 pathway: positive and negative feedback loops

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Cyclins D2 and D1 are essential for postnatal pancreatic beta-cell growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

DeltaNp53 or p44: priming the p53 pump.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Beta cell replication is the primary mechanism for maintaining postnatal beta cell mass.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Regulation of human p53 activity and cell localization by alternative splicing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Modulation of mammalian life span by the short isoform of p53.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

p53 mutant mice that display early ageing-associated phenotypes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Evidence for a circulating islet cell growth factor in insulin-resistant states

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

AFX-like Forkhead transcription factors mediate cell-cycle regulation by Ras and PKB through p27kip1

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Wild-type and mutant p53 differentially regulate transcription of the insulin-like growth factor I receptor gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Growth and regeneration of adult beta cells does not involve specialized progenitors.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Increased islet beta cell replication adjacent to intrapancreatic gastrinomas in humans.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Relationship between beta-cell mass and fasting blood glucose concentration in humans

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Akt induces beta-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Type 2 diabetes-a matter of beta-cell life and death?

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Lilly lecture 2003: the struggle for mastery in insulin action: from triumvirate to republic

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

DeltaN-p53, a natural isoform of p53 lacking the first transactivation domain, counteracts growth suppression by wild-type p53.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Hypoinsulinaemia, glucose intolerance and diminished beta-cell size in S6K1-deficient mice

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

American Diabetes Association diabetes diagnostic criteria, advancing age, and cardiovascular disease risk profiles: results from the Third National Health and Nutrition Examination Survey.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064094

The tumour-suppressor p53 is not required for pancreatic beta cell death during diabetes and upon irradiation

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21357466

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A crucial role for adipose tissue p53 in the regulation of insulin resistance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21357466

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cooperative tumorigenic effects of germline mutations in Rb and p53

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21357466

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.2337/DB09-1379

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

21357466

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21357466%20AND%20SRC:MED&resulttype=core&format=json