Specific increase in potency via structure-based design of a TCR. (Q34383054)

1 August 2017

title

Specific increase in potency via structure-based design of a TCR. (English)

1 reference

1 August 2017

Steven A Rosenberg

1 reference

1 August 2017

Karolina Malecek

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1 August 2017

Arsen Grigoryan

1 reference

1 August 2017

Shi Zhong

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1 August 2017

Wei Jun Gu

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1 August 2017

Laura A Johnson

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1 August 2017

Timothy Cardozo

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1 August 2017

Michelle Krogsgaard

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1 August 2017

language of work or name

English

0 references

publication date

28 July 2014

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1 August 2017

published in

Journal of Immunology

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1 August 2017

volume

193

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1 August 2017

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1 August 2017

page(s)

2587-2599

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Increased peptide contacts govern high affinity binding of a modified TCR whilst maintaining a native pMHC docking mode

1 August 2017

cites work

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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6 July 2018

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27 October 2018

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27 October 2018

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The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge

27 October 2018

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Directed evolution of human T-cell receptors with picomolar affinities by phage display.

27 October 2018

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Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

27 October 2018

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Conversion of a T cell antagonist into an agonist by repairing a defect in the TCR/peptide/MHC interface: implications for TCR signaling.

27 October 2018

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27 October 2018

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27 October 2018

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How the T Cell Repertoire Becomes Peptide and MHC Specific

27 October 2018

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27 October 2018

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27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205480

Different T Cell Receptor Affinity Thresholds and CD8 Coreceptor Dependence Govern Cytotoxic T Lymphocyte Activation and Tetramer Binding Properties

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4205480

PD-1-targeted immunotherapy: recent clinical findings

9 December 2018

1 reference

12 December 2020

TCR binding to peptide-MHC stabilizes a flexible recognition interface

1 reference

12 December 2020

A very high level of crossreactivity is an essential feature of the T-cell receptor

1 reference

12 December 2020

Analysis of endogenous peptides bound by soluble MHC class I molecules: a novel approach for identifying tumor-specific antigens

1 reference

12 December 2020

Improving T cell therapy for cancer

1 reference

12 December 2020

Identifiers

DOI

10.4049/JIMMUNOL.1302344

1 reference

1 August 2017

1 reference

1 August 2017

1 reference