Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury (Q34162118)

31 July 2017

title

Genetic and therapeutic targeting of properdin in mice prevents complement-mediated tissue injury (English)

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31 July 2017

Yuko Kimura

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31 July 2017

Lin Zhou

series ordinal

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31 July 2017

Takashi Miwa

series ordinal

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31 July 2017

Wen-Chao Song

series ordinal

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31 July 2017

language of work or name

English

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publication date

1 October 2010

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Journal of Clinical Investigation

31 July 2017

published in

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31 July 2017

volume

120

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31 July 2017

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31 July 2017

page(s)

3545-3554

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Complement regulators and inhibitory proteins

31 July 2017

cites work

1 reference

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5 July 2018

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5 July 2018

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Complement activation by tubular cells is mediated by properdin binding

5 July 2018

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5 July 2018

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5 July 2018

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The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis.

5 July 2018

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Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation

5 July 2018

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5 July 2018

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Activator-specific requirement of properdin in the initiation and amplification of the alternative pathway complement

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Properdin, a positive regulator of complement activation, is expressed in human T cell lines and peripheral blood T cells

5 July 2018

1 reference

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5 July 2018

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Mouse complement regulatory protein Crry/p65 uses the specific mechanisms of both human decay-accelerating factor and membrane cofactor protein

5 July 2018

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Formation of the initial C3 convertase of the alternative complement pathway. Acquisition of C3b-like activities by spontaneous hydrolysis of the putative thioester in native C3

5 July 2018

1 reference

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5 July 2018

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5 July 2018

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Properdin: binding to C3b and stabilization of the C3b-dependent C3 convertase

5 July 2018

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5 July 2018

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5 July 2018

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28 October 2018

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Properdin can initiate complement activation by binding specific target surfaces and providing a platform for de novo convertase assembly

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947218

Retrovirus-mediated over-expression of decay-accelerating factor rescues Crry-deficient erythrocytes from acute alternative pathway complement attack

28 October 2018

1 reference

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The role of properdin in the assembly of the alternative pathway C3 convertases of complement

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947218

Arthritis critically dependent on innate immune system players

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947218

Conditional gene targeting in macrophages and granulocytes using LysMcre mice.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947218

The fractionation of human plasma proteins. I. Affinity purification of human complement properdin

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2947218

Negligible role of antibodies and C5 in pregnancy loss associated exclusively with C3-dependent mechanisms through complement alternative pathway

28 October 2018

1 reference

12 December 2020

Mouse Crry/p65. Characterization of monoclonal antibodies and the tissue distribution of a functional homologue of human MCP and DAF

1 reference

12 December 2020

Properdin deficiency in a large Swiss family: identification of a stop codon in the properdin gene, and association of meningococcal disease with lack of the IgG2 allotype marker G2m(n)

1 reference

12 December 2020

Arthritis provoked by linked T and B cell recognition of a glycolytic enzyme

1 reference

12 December 2020

Organ-specific disease provoked by systemic autoimmunity

1 reference

12 December 2020

Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils

1 reference

12 December 2020

Properdin system and immunity. II. Interaction of the properdin system with polysaccharides

1 reference

12 December 2020

Association between combined properdin and mannose-binding lectin deficiency and infection with Neisseria meningitidis

1 reference

12 December 2020

1 reference

12 December 2020

Pathogenic complement activation in collagen antibody-induced arthritis in mice requires amplification by the alternative pathway

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI41782

1 reference

31 July 2017

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31 July 2017

1 reference