Mitochondrial pruning by Nix and BNip3: an essential function for cardiac-expressed death factors (Q34121511)

31 July 2017

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title

Mitochondrial pruning by Nix and BNip3: an essential function for cardiac-expressed death factors (English)

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31 July 2017

Gerald W Dorn

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31 July 2017

language of work or name

English

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publication date

16 March 2010

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Journal of Cardiovascular Translational Research

31 July 2017

published in

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31 July 2017

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31 July 2017

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31 July 2017

page(s)

374-383

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Nix is a selective autophagy receptor for mitochondrial clearance

31 July 2017

cites work

1 reference

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Cardiac reanimation: targeting cardiomyocyte death by BNIP3 and NIX/BNIP3L.

28 July 2018

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Nix directly binds to GABARAP: a possible crosstalk between apoptosis and autophagy

28 July 2018

1 reference

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Role of BNIP3 and NIX in cell death, autophagy, and mitophagy

28 July 2018

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Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death

28 July 2018

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Bnip3 functions as a mitochondrial sensor of oxidative stress during myocardial ischemia and reperfusion

28 July 2018

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Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling

28 July 2018

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Cell death by necrosis, a regulated way to go.

28 July 2018

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Essential role for Nix in autophagic maturation of erythroid cells

28 July 2018

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Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation

28 July 2018

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The BCL-2 protein family: opposing activities that mediate cell death

28 July 2018

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The cell cycle factor E2F-1 activates Bnip3 and the intrinsic death pathway in ventricular myocytes

28 July 2018

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NIX is required for programmed mitochondrial clearance during reticulocyte maturation

28 July 2018

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Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice

28 July 2018

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Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure

28 July 2018

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Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis

28 July 2018

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Decompensation of cardiac hypertrophy: cellular mechanisms and novel therapeutic targets

28 July 2018

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Microdomains of intracellular Ca2+: molecular determinants and functional consequences.

28 July 2018

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Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

The pro-cell death Bcl-2 family member, BNIP3, is localized to the nucleus of human glial cells: Implications for glioblastoma multiforme tumor cell survival under hypoxia

28 July 2018

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Physiologic growth and pathologic genes in cardiac development and cardiomyopathy

28 July 2018

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Differential profile of Nix upregulation and translocation during hypoxia/ischaemia in vivo versus in vitro

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Death begets failure in the heart

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Regulation of mitochondrial proliferation in the heart: power-plant failure contributes to cardiac failure in hypertrophy

28 July 2018

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Nuclear localization of the hypoxia-regulated pro-apoptotic protein BNIP3 after global brain ischemia in the rat hippocampus

28 July 2018

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BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Hypoxia and acidosis activate cardiac myocyte death through the Bcl-2 family protein BNIP3.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

HIF-1-dependent regulation of hypoxic induction of the cell death factors BNIP3 and NIX in human tumors.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

NIX induces mitochondrial autophagy in reticulocytes

28 July 2018

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Crossref

https://api.crossref.org/works/10.1007%2FS12265-010-9174-X

Cardiac regeneration: repopulating the heart

21 January 2018

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Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner

28 October 2018

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Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Inducible expression of BNIP3 provokes mitochondrial defects and hypoxia-mediated cell death of ventricular myocytes.

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

28 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2900478

Overexpression of Bcl-2 attenuates apoptosis and protects against myocardial I/R injury in transgenic mice

28 October 2018

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Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores

28 October 2018

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12 December 2020

Side-to-side slippage of myocytes participates in ventricular wall remodeling acutely after myocardial infarction in rats

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12 December 2020

Human pathologic correlation with PET in ischemic and nonischemic cardiomyopathy

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12 December 2020

Apoptosis in the failing human heart

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12 December 2020

Changing the remodeling process in heart failure: basic mechanisms and laboratory results

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12 December 2020

Increased cardiomyocyte apoptosis and changes in proapoptotic and antiapoptotic genes bax and bcl-2 during left ventricular adaptations to chronic pressure overload in the rat

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12 December 2020

Physiological growth synergizes with pathological genes in experimental cardiomyopathy

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12 December 2020

10.1007/S12265-010-9174-X

Identifiers

DOI

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Dimensions Publication ID

31 July 2017

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31 July 2017

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