Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis (Q33854131)

29 July 2017

title

Bax forms multispanning monomers that oligomerize to permeabilize membranes during apoptosis (English)

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29 July 2017

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Erinn L Soucie

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Linda Z Penn

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David William Andrews

David W Andrews

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Matthew G Annis

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29 July 2017

Paulina J Dlugosz

series ordinal

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29 July 2017

Jorge A Cruz-Aguado

series ordinal

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29 July 2017

Brian Leber

series ordinal

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29 July 2017

language of work or name

English

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publication date

26 May 2005

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29 July 2017

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

2096-2103

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During apoptosis bcl-2 changes membrane topology at both the endoplasmic reticulum and mitochondria

29 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Interaction with a membrane surface triggers a reversible conformational change in Bax normally associated with induction of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

BCL-2 Selectively Interacts with the BID-induced Open Conformer of BAK, Inhibiting BAK Auto-oligomerization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

The N-terminal end of Bax contains a mitochondrial-targeting signal.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Myc potentiates apoptosis by stimulating Bax activity at the mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Structure of Bax: coregulation of dimer formation and intracellular localization

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

The putative pore-forming domain of Bax regulates mitochondrial localization and interaction with Bcl-X(L).

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Conformation of the Bax C-terminus regulates subcellular location and cell death

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Bid-induced conformational change of Bax is responsible for mitochondrial cytochrome c release during apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Regulated targeting of BAX to mitochondria.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Movement of Bax from the cytosol to mitochondria during apoptosis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Lipidic pore formation by the concerted action of proapoptotic BAX and tBID.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Bcl-2 and Bax modulate adenine nucleotide translocase activity.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Endoplasmic reticulum localized Bcl-2 prevents apoptosis when redistribution of cytochrome c is a late event

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Characterization of high-order diphtheria toxin oligomers

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Diphtheria toxin forms pores of different sizes depending on its concentration in membranes: probable relationship to oligomerization

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1150878

Primary cells suppress oncogene-dependent apoptosis

29 October 2018

1 reference

12 December 2020

Direct evidence for membrane pore formation by the apoptotic protein Bax

1 reference

12 December 2020

Membrane-insertion fragments of Bcl-xL, Bax, and Bid

1 reference

12 December 2020

Unfolding pathway of the colicin E1 channel protein on a membrane surface

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600675

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29 July 2017

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29 July 2017

1 reference