Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner (Q33724405)

28 July 2017

title

Transforming growth factor beta facilitates beta-TrCP-mediated degradation of Cdc25A in a Smad3-dependent manner (English)

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28 July 2017

Giulio F Draetta

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28 July 2017

Dipankar Ray

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28 July 2017

Yasuhisa Terao

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28 July 2017

Dipali Nimbalkar

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28 July 2017

Li-Hao Chu

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28 July 2017

Maddalena Donzelli

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28 July 2017

Tateki Tsutsui

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28 July 2017

Xianghong Zou

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28 July 2017

Asish K Ghosh

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28 July 2017

John Varga

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28 July 2017

Hiroaki Kiyokawa

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28 July 2017

language of work or name

English

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publication date

1 April 2005

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Molecular and Cellular Biology

28 July 2017

published in

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

3338-3347

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Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1

28 July 2017

cites work

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SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Chk1 is activated transiently and targets Cdc25A for degradation at the Xenopus midblastula transition

21 June 2018

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E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

21 June 2018

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Smad3 recruits the anaphase-promoting complex for ubiquitination and degradation of SnoN

21 June 2018

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Cdc25A phosphatase suppresses apoptosis induced by serum deprivation

21 June 2018

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21 June 2018

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The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1

21 June 2018

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Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

21 June 2018

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Ligand-dependent degradation of Smad3 by a ubiquitin ligase complex of ROC1 and associated proteins

21 June 2018

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Transforming growth factor: signal transduction pathways, cell cycle mediation, and effects on hematopoiesis

21 June 2018

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Multifaceted regulation of cell cycle progression by estrogen: regulation of Cdk inhibitors and Cdc25A independent of cyclin D1-Cdk4 function

21 June 2018

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A novel ability of Smad3 to regulate proteasomal degradation of a Cas family member HEF1

21 June 2018

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Role of the Cdc25A phosphatase in human breast cancer

21 June 2018

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Cell cycle regulation by the Cdc25 phosphatase family

21 June 2018

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

21 June 2018

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21 June 2018

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Ectopic expression of Cdc25A accelerates the G(1)/S transition and leads to premature activation of cyclin E- and cyclin A-dependent kinases

21 June 2018

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Targeted disruption of Smad3 reveals an essential role in transforming growth factor beta-mediated signal transduction

21 June 2018

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Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

21 June 2018

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E2F and histone deacetylase mediate transforming growth factor beta repression of cdc25A during keratinocyte cell cycle arrest

21 June 2018

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Smad3 mutant mice develop metastatic colorectal cancer

21 June 2018

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins

21 June 2018

1 reference

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Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

21 June 2018

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Cdc25 protein phosphatases in cell proliferation

21 June 2018

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Cdc25A is a novel phosphatase functioning early in the cell cycle

21 June 2018

1 reference

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CDC25 phosphatases as potential human oncogenes

21 June 2018

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Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

21 June 2018

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Loss of Smad3 in acute T-cell lymphoblastic leukemia.

21 June 2018

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Cyclin-dependent kinases regulate the antiproliferative function of Smads

30 October 2018

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Cdc25A and cdc25B expression in malignant lymphoma of the thyroid: correlation with histological subtypes and cell proliferation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069597

Hierarchical order of phosphorylation events commits Cdc25A to betaTrCP-dependent degradation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069597

Loss of the Smad3 expression increases susceptibility to tumorigenicity in human gastric cancer.

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069597

30 October 2018

1 reference

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Cdc25A stability is controlled by the ubiquitin-proteasome pathway during cell cycle progression and terminal differentiation.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1069597

Reduction of Cdc25A contributes to cyclin E1-Cdk2 inhibition at senescence in human mammary epithelial cells

30 October 2018

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12 December 2020

Distinct modes of deregulation of the proto-oncogenic Cdc25A phosphatase in human breast cancer cell lines

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12 December 2020

CDC25A Mediates Survival by Activating AKT Kinase

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12 December 2020

Overexpression of CDC25A and CDC25B in head and neck cancers

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12 December 2020

Elevated expression of the cdc25A protein phosphatase in colon cancer

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12 December 2020

Overexpression of cdc25A and cdc25B is frequent in primary non-small cell lung cancer but is not associated with overexpression of c-myc

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12 December 2020

Stimulation of Type I Collagen Transcription in Human Skin Fibroblasts by TGF-β: Involvement of Smad 3

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12 December 2020

10.1128/MCB.25.8.3338-3347.2005

Identifiers

DOI

1 reference

28 July 2017

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28 July 2017

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