Elimination of IL-10-inducing T-helper epitopes from an IGFBP-2 vaccine ensures potent antitumor activity. (Q33679779)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24778415%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

title

Elimination of IL-10-inducing T-helper epitopes from an IGFBP-2 vaccine ensures potent antitumor activity (English)

1 reference

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16 March 2020

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16 March 2020

Denise L Cecil

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16 March 2020

Kyong Hwa Park

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16 March 2020

Ekram Gad

1 reference

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16 March 2020

Lauren Rastetter

1 reference

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16 March 2020

Jennifer Childs

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16 March 2020

Doreen Higgins

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16 March 2020

Mary L Disis

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16 March 2020

language of work or name

English

0 references

publication date

28 April 2014

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16 March 2020

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16 March 2020

volume

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16 March 2020

issue

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16 March 2020

page(s)

2710-2718

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Key roles of adjuvants in modern vaccines

16 March 2020

cites work

1 reference

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A multiantigen vaccine targeting neu, IGFBP-2, and IGF-IR prevents tumor progression in mice with preinvasive breast disease

21 June 2018

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Messenger RNA vaccine based on recombinant MS2 virus-like particles against prostate cancer

21 June 2018

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HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients

21 June 2018

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TH2 cytokines from malignant cells suppress TH1 responses and enforce a global TH2 bias in leukemic cutaneous T-cell lymphoma

21 June 2018

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High-avidity T cells are preferentially tolerized in the tumor microenvironment

21 June 2018

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A cancer vaccine induces expansion of NY-ESO-1-specific regulatory T cells in patients with advanced melanoma.

21 June 2018

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High avidity cytotoxic T lymphocytes can be selected into the memory pool but they are exquisitely sensitive to functional impairment

21 June 2018

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21 June 2018

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21 June 2018

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Thymic stromal lymphopoietin fosters human breast tumor growth by promoting type 2 inflammation

21 June 2018

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Reduced functional avidity promotes central and effector memory CD4 T cell responses to tumor-associated antigens

21 June 2018

1 reference

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Vaccination of Metastatic Renal Cancer Patients with MVA-5T4: A Randomized, Double-Blind, Placebo-Controlled Phase III Study

21 June 2018

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Inflammatory cytokines as a third signal for T cell activation

21 June 2018

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Signals that influence T follicular helper cell differentiation and function.

21 June 2018

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Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia

21 June 2018

1 reference

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Value of eight-amino-acid matches in predicting the allergenicity status of proteins: an empirical bioinformatic investigation

21 June 2018

1 reference

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Concurrent trastuzumab and HER2/neu-specific vaccination in patients with metastatic breast cancer

21 June 2018

1 reference

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Dendritic cells in immunotherapy of established cancer: Roles of signals 1, 2, 3 and 4

21 June 2018

1 reference

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Insulin-like growth factor-binding protein-2 is a target for the immunomodulation of breast cancer

21 June 2018

1 reference

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An adjuvant autologous therapeutic vaccine (HSPPC-96; vitespen) versus observation alone for patients at high risk of recurrence after nephrectomy for renal cell carcinoma: a multicentre, open-label, randomised phase III trial

21 June 2018

1 reference

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Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma

21 June 2018

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Breast cancer instructs dendritic cells to prime interleukin 13-secreting CD4+ T cells that facilitate tumor development

21 June 2018

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Paradoxical effects of cytokines in tumor immune surveillance and tumor immune escape

21 June 2018

1 reference

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Type, density, and location of immune cells within human colorectal tumors predict clinical outcome

21 June 2018

1 reference

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Neu antigen-negative variants can be generated after neu-specific antibody therapy in neu transgenic mice

21 June 2018

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Adjuvant immunotherapy of resected, intermediate-thickness, node-negative melanoma with an allogeneic tumor vaccine: overall results of a randomized trial of the Southwest Oncology Group

21 June 2018

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Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo

21 June 2018

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Th1 cytokines are more effective than Th2 cytokines at licensing anti-tumour functions in CD40-activated human macrophages in vitro

21 June 2018

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Generation and immunosuppressive functions of p53-induced human adaptive regulatory T cells

30 October 2018

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Adjuvants that improve the ratio of antigen-specific effector to regulatory T cells enhance tumor immunity.

30 October 2018

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T-helper I immunity, specific for the breast cancer antigen insulin-like growth factor-I receptor (IGF-IR), is associated with increased adiposity

30 October 2018

1 reference

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Interpreting the biological relevance of bioinformatic analyses with T-DNA sequence for protein allergenicity

30 October 2018

1 reference

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Dominant Th2 differentiation of human regulatory T cells upon loss of FOXP3 expression.

30 October 2018

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Maximizing the retention of antigen specific lymphocyte function after cryopreservation.

30 October 2018

1 reference

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A key role for ICAM-1 in generating effector cells mediating inflammatory responses

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4037234

TGF-beta contributes to the shift toward Th2-type responses through direct and IL-10-mediated pathways in tumor-bearing mice

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24778415

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/0008-5472.CAN-13-3286

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24778415%20AND%20SRC:MED&resulttype=core&format=json

16 March 2020

1 reference

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16 March 2020

PubMed publication ID

24778415

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24778415%20AND%20SRC:MED&resulttype=core&format=json