An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling (Q33615675)

28 July 2017

title

An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling (English)

1 reference

28 July 2017

Borries Demeler

1 reference

28 July 2017

Sun Kyung Kim

1 reference

28 July 2017

Lindsey Barron

1 reference

28 July 2017

Cynthia S Hinck

1 reference

28 July 2017

Elyse M Petrunak

1 reference

28 July 2017

Kristin E Cano

1 reference

28 July 2017

Avinash Thangirala

1 reference

28 July 2017

Brian Iskra

1 reference

28 July 2017

Molly Brothers

1 reference

28 July 2017

Machell Vonberg

1 reference

28 July 2017

Belinda Leal

1 reference

28 July 2017

Blair Richter

1 reference

28 July 2017

Ravindra Kodali

1 reference

28 July 2017

Alexander B Taylor

1 reference

28 July 2017

Shoucheng Du

1 reference

28 July 2017

Christopher O Barnes

1 reference

28 July 2017

Traian Sulea

1 reference

28 July 2017

Guillermo Calero

1 reference

28 July 2017

P John Hart

1 reference

28 July 2017

Matthew J Hart

1 reference

28 July 2017

Andrew P Hinck

1 reference

28 July 2017

language of work or name

English

0 references

publication date

22 February 2017

1 reference

Journal of Biological Chemistry

28 July 2017

published in

1 reference

28 July 2017

volume

292

1 reference

28 July 2017

1 reference

28 July 2017

page(s)

7173-7188

1 reference

Sparse multidimensional iterative lineshape-enhanced (SMILE) reconstruction of both non-uniformly sampled and conventional NMR data

28 July 2017

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1 reference

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21 June 2018

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Structural Biology and Evolution of the TGF-β Family

21 June 2018

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Production, Isolation, and Structural Analysis of Ligands and Receptors of the TGF-β Superfamily

21 June 2018

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21 June 2018

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Transforming growth factor-beta1 signaling blockade attenuates gastric cancer cell-induced peritoneal mesothelial cell fibrosis and alleviates peritoneal dissemination both in vitro and in vivo

21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs

21 June 2018

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Outgrowth of drug-resistant carcinomas expressing markers of tumor aggression after long-term TβRI/II kinase inhibition with LY2109761.

21 June 2018

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Targeting the Transforming Growth Factor-beta pathway inhibits human basal-like breast cancer metastasis.

21 June 2018

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Methods for the design and analysis of sedimentation velocity and sedimentation equilibrium experiments with proteins

21 June 2018

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21 June 2018

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Ternary Complex of Transforming Growth Factor- 1 Reveals Isoform-specific Ligand Recognition and Receptor Recruitment in the Superfamily

21 June 2018

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PHENIX: a comprehensive Python-based system for macromolecular structure solution

21 June 2018

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21 June 2018

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21 June 2018

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TbetaR-II discriminates the high- and low-affinity TGF-beta isoforms via two hydrogen-bonded ion pairs

21 June 2018

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21 June 2018

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An anti-transforming growth factor beta antibody suppresses metastasis via cooperative effects on multiple cell compartments.

21 June 2018

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Modeling analytical ultracentrifugation experiments with an adaptive space-time finite element solution for multicomponent reacting systems

21 June 2018

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Cooperative assembly of TGF-beta superfamily signaling complexes is mediated by two disparate mechanisms and distinct modes of receptor binding

21 June 2018

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Gene transfer of soluble transforming growth factor type II receptor by in vivo electroporation attenuates lung injury and fibrosis

21 June 2018

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Aneurysm syndromes caused by mutations in the TGF-beta receptor

21 June 2018

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Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

21 June 2018

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Development of TGF-beta signalling inhibitors for cancer therapy

21 June 2018

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Overexpression of human transforming growth factor-beta1 using a recombinant CHO cell expression system

21 June 2018

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Transforming the TGFbeta pathway: convergence of distinct lead generation strategies on a novel kinase pharmacophore for TbetaRI (ALK5).

21 June 2018

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The 1.1 A crystal structure of human TGF-beta type II receptor ligand binding domain

21 June 2018

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Lifetime exposure to a soluble TGF-beta antagonist protects mice against metastasis without adverse side effects

21 June 2018

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Blockade of TGF-beta inhibits mammary tumor cell viability, migration, and metastases.

21 June 2018

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Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex

21 June 2018

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GDF-8 propeptide binds to GDF-8 and antagonizes biological activity by inhibiting GDF-8 receptor binding

21 June 2018

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Biotinylation of proteins in vivo and in vitro using small peptide tags

21 June 2018

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TGF-beta signal transduction

21 June 2018

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Tumor suppressor activity of the TGF-beta pathway in human cancers

21 June 2018

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The crystal structure of TGF-beta 3 and comparison to TGF-beta 2: implications for receptor binding

21 June 2018

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Transforming growth factor beta 1: three-dimensional structure in solution and comparison with the X-ray structure of transforming growth factor beta 2

21 June 2018

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21 June 2018

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21 June 2018

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Mechanism of activation of the TGF-beta receptor

21 June 2018

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21 June 2018

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Backbone dynamics of proteins as studied by 15N inverse detected heteronuclear NMR spectroscopy: application to staphylococcal nuclease

21 June 2018

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Responsiveness to transforming growth factor-beta (TGF-beta) restored by genetic complementation between cells defective in TGF-beta receptors I and II

21 June 2018

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Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily

21 June 2018

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TGF beta signals through a heteromeric protein kinase receptor complex

21 June 2018

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Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene

21 June 2018

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Assembly of TbetaRI:TbetaRII:TGFbeta ternary complex in vitro with receptor extracellular domains is cooperative and isoform-dependent

28 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.768754

Transforming growth factor beta signalling and matrix metalloproteinases in the mucosa overlying Crohn's disease strictures.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.768754

Selective inhibitors of type I receptor kinase block cellular transforming growth factor-beta signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.768754

Activin signaling through activin receptor type II causes the cachexia-like symptoms in inhibin-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.768754

Characterization of reversible associations by sedimentation velocity with UltraScan.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.768754

Three-dimensional triple-resonance NMR spectroscopy of isotopically enriched proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M116.768754

Sequential resonance assignments of the extracellular ligand binding domain of the human TGF-beta type II receptor

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28228478

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Three key residues underlie the differential affinity of the TGFbeta isoforms for the TGFbeta type II receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28228478

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Conformation and self-association of human recombinant transforming growth factor-beta3 in aqueous solutions

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28228478

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M116.768754

1 reference

28 July 2017

1 reference

28 July 2017

1 reference