Integrative analysis of RUNX1 downstream pathways and target genes (Q33356764)

26 July 2017

title

Integrative analysis of RUNX1 downstream pathways and target genes (English)

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26 July 2017

Matthew E Ritchie

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Marshall S Horwitz

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Hamish S Scott

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Gordon K Smyth

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Terence P Speed

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26 July 2017

Maria Kavallaris

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26 July 2017

Joëlle Michaud

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26 July 2017

Ken M Simpson

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26 July 2017

Robert Escher

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26 July 2017

Karine Buchet-Poyau

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26 July 2017

Tim Beissbarth

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26 July 2017

Catherine Carmichael

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26 July 2017

Frédéric Schütz

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26 July 2017

Ping Cannon

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26 July 2017

Marjorie Liu

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26 July 2017

Xiaofeng Shen

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26 July 2017

Yoshiaki Ito

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26 July 2017

Wendy H Raskind

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26 July 2017

Motomi Osato

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26 July 2017

David R Turner

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26 July 2017

language of work or name

English

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publication date

31 July 2008

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26 July 2017

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26 July 2017

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26 July 2017

page(s)

363

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describes a project that uses

26 July 2017

limma

object named as

LIMMA

2 references

22 June 2022

https://europepmc.org/article/PMC/2529319

inferred from PubMed Central ID database lookup

CZ Software Mentions: A large dataset of software mentions in the biomedical literature

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14 July 2018

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14 July 2018

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A differential gene expression profile reveals overexpression of RUNX1/AML1 in invasive endometrioid carcinoma.

14 July 2018

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14 July 2018

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14 July 2018

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Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer.

14 July 2018

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Dynamic microtubules lead the way for spindle positioning.

14 July 2018

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Point mutations in the RUNX1/AML1 gene: another actor in RUNX leukemia

14 July 2018

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Structure and regulated expression of mammalian RUNX genes

14 July 2018

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Microtubules as a target for anticancer drugs

14 July 2018

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GOstat: find statistically overrepresented Gene Ontologies within a group of genes

14 July 2018

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AML1/RUNX1 increases during G1 to S cell cycle progression independent of cytokine-dependent phosphorylation and induces cyclin D3 gene expression

14 July 2018

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Acute myeloid leukemia fusion proteins deregulate genes involved in stem cell maintenance and DNA repair

14 July 2018

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Normalization of cDNA microarray data

14 July 2018

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Annexin 1 regulates cell proliferation by disruption of cell morphology and inhibition of cyclin D1 expression through sustained activation of the ERK1/2 MAPK signal

14 July 2018

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Expression of myotubularin by an adenoviral vector demonstrates its function as a phosphatidylinositol 3-phosphate [PtdIns(3)P] phosphatase in muscle cell lines: involvement of PtdIns(3)P in insulin-stimulated glucose transport

14 July 2018

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14 July 2018

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AML1 interconnected pathways of leukemogenesis

14 July 2018

1 reference

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Summaries of Affymetrix GeneChip probe level data

14 July 2018

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New mechanisms of AML1 gene alteration in hematological malignancies

14 July 2018

1 reference

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AML1 gene over-expression in childhood acute lymphoblastic leukemia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

In vitro analyses of known and novel RUNX1/AML1 mutations in dominant familial platelet disorder with predisposition to acute myelogenous leukemia: implications for mechanisms of pathogenesis

14 July 2018

1 reference

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AML1-ETO expression is directly involved in the development of acute myeloid leukemia in the presence of additional mutations

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Mutations in MYH9 result in the May-Hegglin anomaly, and Fechtner and Sebastian syndromes. The May-Heggllin/Fechtner Syndrome Consortium

14 July 2018

1 reference

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Isolation and characterization of a human chromosome 21q22.3 gene (WDR4) and its mouse homologue that code for a WD-repeat protein

14 July 2018

1 reference

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Hematopoietic-specific beta 1 tubulin participates in a pathway of platelet biogenesis dependent on the transcription factor NF-E2.

14 July 2018

1 reference

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Accommodating haploinsufficient tumor suppressor genes in Knudson's model

14 July 2018

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Role of the transcription factor AML-1 in acute leukemia and hematopoietic differentiation

14 July 2018

1 reference

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Expression of the AML-1 oncogene shortens the G(1) phase of the cell cycle

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Cbfa2 is required for the formation of intra-aortic hematopoietic clusters.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Somatic cell mutations in cancer epidemiology

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

The protooncogene product, PEBP2beta/CBFbeta, is mainly located in the cytoplasm and has an affinity with cytoskeletal structures

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Lipocortin-1 fragments inhibit neutrophil accumulation and neutrophil-dependent edema in the mouse. A qualitative comparison with an anti-CD11b monoclonal antibody.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Isolation of a novel gene mutated in Wiskott-Aldrich syndrome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Use of within-array replicate spots for assessing differential expression in microarray experiments

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Prognostically useful gene-expression profiles in acute myeloid leukemia.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Microtubule alterations and mutations induced by desoxyepothilone B: implications for drug-target interactions

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Analysis of the role of AML1-ETO in leukemogenesis, using an inducible transgenic mouse model

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

AML1(-/-) embryos do not express certain hematopoiesis-related gene transcripts including those of the PU.1 gene.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2529319

Architecture and anatomy of the genomic locus encoding the human leukemia-associated transcription factor RUNX1/AML1

31 October 2018

1 reference

12 December 2020

Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2alphaB gene associated with myeloblastic leukemias

1 reference

12 December 2020

The fusion gene Cbfb-MYH11 blocks myeloid differentiation and predisposes mice to acute myelomonocytic leukaemia

1 reference

12 December 2020

CBF beta-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells

1 reference

12 December 2020

Development of a human acute myeloid leukaemia screening panel and consequent identification of novel gene mutation in FLT3 and CCND3

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2164-9-363

1 reference

Dimensions Publication ID

26 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-9-363

9 September 2019

1 reference

26 July 2017

1 reference