The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth (Q33328513)

25 July 2017

title

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth (English)

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25 July 2017

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25 July 2017

Rafael de Cabo

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Shuji Ogino

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Charles Fuchs

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25 July 2017

William C Hahn

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25 July 2017

Leonard P Guarente

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25 July 2017

Anupama Bhimavarapu

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25 July 2017

Ron Firestein

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25 July 2017

Gil Blander

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25 July 2017

Shaday Michan

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25 July 2017

Philipp Oberdoerffer

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Jennifer Campbell

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25 July 2017

Sandra Luikenhuis

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25 July 2017

language of work or name

English

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publication date

16 April 2008

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25 July 2017

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25 July 2017

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25 July 2017

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25 July 2017

page(s)

e2020

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Creative Commons Attribution 4.0 International

25 July 2017

start time

16 April 2008

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April 2022 Public Data File from Crossref

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2289879/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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28 July 2018

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28 July 2018

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Combined analysis of COX-2 and p53 expressions reveals synergistic inverse correlations with microsatellite instability and CpG island methylator phenotype in colorectal cancer

28 July 2018

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Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

28 July 2018

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28 July 2018

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Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

28 July 2018

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Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

28 July 2018

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Association of the APC gene product with beta-catenin

28 July 2018

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Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

28 July 2018

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Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene

28 July 2018

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SIRT1 acts as a nutrient-sensitive growth suppressor and its loss is associated with increased AMPK and telomerase activity

28 July 2018

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Sirtuins: critical regulators at the crossroads between cancer and aging

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Sirtuin functions in health and disease

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Sirt1 regulates aging and resistance to oxidative stress in the heart

31 October 2018

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SIRT1 interacts with p73 and suppresses p73-dependent transcriptional activity

31 October 2018

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31 October 2018

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Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

31 October 2018

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Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress

31 October 2018

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31 October 2018

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

31 October 2018

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31 October 2018

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Mammalian SIRT1 represses forkhead transcription factors

31 October 2018

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Calorie restriction and diet composition modulate spontaneous intestinal tumorigenesis in Apc(Min) mice through different mechanisms

31 October 2018

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31 October 2018

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31 October 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/18414679

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0002020

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25 July 2017

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25 July 2017

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