Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework (Q32034964)

5 July 2017

title

Exploiting sequence space: shuffling in vivo formed complementarity determining regions into a master framework (English)

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5 July 2017

Ohlin M

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5 July 2017

Jirholt P

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5 July 2017

Borrebaeck CA

series ordinal

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5 July 2017

Söderlind E

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5 July 2017

language of work or name

English

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publication date

1 July 1998

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5 July 2017

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5 July 2017

volume

215

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5 July 2017

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5 July 2017

page(s)

471-476

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Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problem

5 July 2017

cites work

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The human immunoglobulin VH repertoire

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Antibody VH domains as small recognition units

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Isolation of high affinity human antibodies directly from large synthetic repertoires.

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Non-stochastic utilization of Ig V region genes in unselected human peripheral B cells.

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Analysis of assembly of synthetic antibody fragments: expression of functional scFv with predefined specificity

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7 January 2021

Characteristics of human antibody repertoires following active immune responses in vivo

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Light chain shuffling of a high affinity antibody results in a drift in epitope recognition

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7 January 2021

New protein engineering approaches to multivalent and bispecific antibody fragments

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Rapid evolution of a protein in vitro by DNA shuffling

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7 January 2021

Domain libraries: Synthetic diversity for de novo design of antibody V-regions

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Fidelity of DNA synthesis by the Thermus aquaticus DNA polymerase

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Trinucleotide phosphoramidites: ideal reagents for the synthesis of mixed oligonucleotides for random mutagenesis

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Length distribution of CDRH3 in antibodies

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Molecular evolution by staggered extension process (StEP) in vitro recombination

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7 January 2021

10.1016/S0378-1119(98)00317-5

Identifiers

DOI

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5 July 2017

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