Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession (Q30537554)

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English	Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

15 August 2017

Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

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Alzheimer's disease

1 reference

based on heuristic

inferred from title

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1 reference

based on heuristic

inferred from title

8

object named as

Mark P Mattson

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Europe PubMed Central

PMC publication ID

15 August 2017

author name string

Dong Liu

1

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Michael Pitta

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Haiyang Jiang

3

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Jong-Hwan Lee

4

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Guofeng Zhang

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Xinzhi Chen

6

1 reference

Europe PubMed Central

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15 August 2017

Elisa M Kawamoto

7

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Europe PubMed Central

PMC publication ID

15 August 2017

publication date

25 December 2012

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Europe PubMed Central

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15 August 2017

Neurobiology of Aging

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Europe PubMed Central

PMC publication ID

15 August 2017

34

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Europe PubMed Central

PMC publication ID

15 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1564-1580

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Europe PubMed Central

PMC publication ID

15 August 2017

The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity

1 reference

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A reversible early oxidized redox state that precedes macromolecular ROS damage in aging nontransgenic and 3xTg-AD mouse neurons

1 reference

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Nicotinamide-induced mitophagy: event mediated by high NAD+/NADH ratio and SIRT1 protein activation

1 reference

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Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

1 reference

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Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits

1 reference

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Autophagy and aging

1 reference

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Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease

1 reference

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CREB and ChREBP oppositely regulate SIRT1 expression in response to energy availability

1 reference

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Lysosomal proteolysis inhibition selectively disrupts axonal transport of degradative organelles and causes an Alzheimer's-like axonal dystrophy

1 reference

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Autophagy in the cellular energetic balance

1 reference

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Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage

1 reference

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Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons

1 reference

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1 reference

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Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits

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Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease

1 reference

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Neuroprotective strategies involving ROS in Alzheimer disease

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CREB: a multifaceted regulator of neuronal plasticity and protection

1 reference

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Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications

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Mitochondrial autophagy in neural function, neurodegenerative disease, neuron cell death, and aging

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The KATP Channel Activator Diazoxide Ameliorates Amyloid-β and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer's Disease

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Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions.

1 reference

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Nicotinamide improves motor deficits and upregulates PGC-1α and BDNF gene expression in a mouse model of Huntington's disease

1 reference

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Insulin signaling meets mitochondria in metabolism

1 reference

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A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions

1 reference

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Autophagy in Alzheimer's disease

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Autophagy gone awry in neurodegenerative diseases

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Autophagy dysfunction in Alzheimer's disease

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Lysosomal proteolysis and autophagy require presenilin 1 and are disrupted by Alzheimer-related PS1 mutations

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Termination of autophagy and reformation of lysosomes regulated by mTOR

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Induction of reactive oxygen species-mediated autophagy by a novel microtubule-modulating agent

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Review: autophagy and neurodegeneration: survival at a cost?

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NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death

1 reference

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1 reference

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Role of oxidative stress in the progression of Alzheimer's disease

1 reference

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Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes.

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Simvastatin-mediated upregulation of VEGF and BDNF, activation of the PI3K/Akt pathway, and increase of neurogenesis are associated with therapeutic improvement after traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

Inappropriate activation of the TSC/Rheb/mTOR/S6K cassette induces IRS1/2 depletion, insulin resistance, and cell survival deficiencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

Regulation of brain mitochondrial H2O2 production by membrane potential and NAD(P)H redox state.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

beta-Amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

Oxidative damage is the earliest event in Alzheimer disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

Mitochondrial abnormalities in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

Deficits in cerebral glucose metabolism demonstrated by positron emission tomography in individuals at risk of familial Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3596471

26 November 2018

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23273573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NAD+ treatment induces delayed autophagy in Neuro2a cells partially by increasing oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/23273573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc-induced cortical neuronal death: contribution of energy failure attributable to loss of NAD(+) and inhibition of glycolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23273573

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.NEUROBIOLAGING.2012.11.020

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

0 references

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