The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion Diseases (Q30234448)

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English	The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion Diseases	scientific article

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507517%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

1 reference

Europe PubMed Central

The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion Diseases (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507517%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

prion protein family

0 references

neurodegeneration

1 reference

based on heuristic

inferred from title

Syed Zahid Ali Shah

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507517%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

author name string

Deming Zhao

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507517%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Tariq Hussain

3

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507517%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

Lifeng Yang

4

1 reference

Europe PubMed Central

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20 March 2020

publication date

1 May 2017

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Europe PubMed Central

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20 March 2020

Frontiers in Aging Neuroscience

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Europe PubMed Central

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20 March 2020

9

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20 March 2020

120

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PMC publication ID

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20 March 2020

Arsenic trioxide mediates HAPI microglia inflammatory response and subsequent neuron apoptosis through p38/JNK MAPK/STAT3 pathway

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3 June 2018

Secretory pathway retention of mutant prion protein induces p38-MAPK activation and lethal disease in mice

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3 June 2018

The stress of prion disease

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REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling

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3 June 2018

Suppression of MAPK attenuates neuronal cell death induced by activated glia-conditioned medium in alpha-synuclein overexpressing SH-SY5Y cells.

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Prion Infectivity Plateaus and Conversion to Symptomatic Disease Originate from Falling Precursor Levels and Increased Levels of Oligomeric PrPSc Species.

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Unfolded Protein Response Pathways in Neurodegenerative Diseases.

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p38 MAPK and PI3K/AKT Signalling Cascades inParkinson's Disease

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Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity

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Compromised MAPK signaling in human diseases: an update

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Pathological axonal death through a MAPK cascade that triggers a local energy deficit

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Mitogen-activated protein kinase signaling pathways are involved in regulating α7 nicotinic acetylcholine receptor-mediated amyloid-β uptake in SH-SY5Y cells

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A novel synthetic HTB derivative, BECT inhibits lipopolysaccharide-mediated inflammatory response by suppressing the p38 MAPK/JNK and NF-κB activation pathways.

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p38 MAPK and ERK1/2 pathways are involved in the pro-apoptotic effect of notoginsenoside Ft1 on human neuroblastoma SH-SY5Y cells

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Nuclear and cytosolic JNK signalling in neurons

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3 June 2018

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases

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3 June 2018

The role of MAPK signalling pathways in the response to endoplasmic reticulum stress

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3 June 2018

Tau in MAPK activation

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3 June 2018

Oral treatment targeting the unfolded protein response prevents neurodegeneration and clinical disease in prion-infected mice

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3 June 2018

Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T.

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3 June 2018

MAP kinase phosphatase 1 (MKP-1/DUSP1) is neuroprotective in Huntington's disease via additive effects of JNK and p38 inhibition

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3 June 2018

Snord 3A: a molecular marker and modulator of prion disease progression

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3 June 2018

Critical role of p38 MAPK for regeneration of the sciatic nerve following crush injury in vivo

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The Role of p38 MAPK and Its Substrates in Neuronal Plasticity and Neurodegenerative Disease

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3 June 2018

Sustained translational repression by eIF2α-P mediates prion neurodegeneration

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3 June 2018

Over-expression of map kinase phosphatase-1 (MKP-1) suppresses neuronal death through regulating JNK signaling in hypoxia/re-oxygenation

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3 June 2018

Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons

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3 June 2018

Axon regeneration requires coordinate activation of p38 and JNK MAPK pathways

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3 June 2018

Role of calcineurin in neurodegeneration produced by misfolded proteins and endoplasmic reticulum stress

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3 June 2018

Curcumin enhances neuronal survival in N-methyl-d-aspartic acid toxicity by inducing RANTES expression in astrocytes via PI-3K and MAPK signaling pathways

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3 June 2018

Calcineurin Inhibition at the Clinical Phase of Prion Disease Reduces Neurodegeneration, Improves Behavioral Alterations and Increases Animal Survival

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The MAP kinase phosphatase MKP-1 regulates BDNF-induced axon branching

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The intricate mechanisms of neurodegeneration in prion diseases.

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Differential regulation of AKT, MAPK and GSK3β during C2-ceramide-induced neuronal death

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3 June 2018

Memory impairment in transgenic Alzheimer mice requires cellular prion protein

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3 June 2018

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The c-Jun N-terminal kinase 1 (JNK1) in spinal astrocytes is required for the maintenance of bilateral mechanical allodynia under a persistent inflammatory pain condition

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Cellular prion protein mediates impairment of synaptic plasticity by amyloid-beta oligomers

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Endocytosis of prion protein is required for ERK1/2 signaling induced by stress-inducible protein 1.

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Role of Erk1/2 activation in prion disease pathogenesis: absence of CCR1 leads to increased Erk1/2 activation and accelerated disease progression

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3 June 2018

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3 June 2018

Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis.

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3 June 2018

Resistance of cell lines to prion toxicity aided by phospho-ERK expression

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3 June 2018

Involvement of mitochondria in endoplasmic reticulum stress-induced apoptotic cell death pathway triggered by the prion peptide PrP(106-126).

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3 June 2018

A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model.

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3 June 2018

Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein

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3 June 2018

MKP-1 contributes to oxidative stress-induced apoptosis via inactivation of ERK1/2 in SH-SY5Y cells

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3 June 2018

Nitric oxide induces prion protein via MEK and p38 MAPK signaling

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3 June 2018

MKP-8, a novel MAPK phosphatase that inhibits p38 kinase

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3 June 2018

Activation and signaling of the p38 MAP kinase pathway

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3 June 2018

Prion replication alters the distribution of synaptophysin and caveolin 1 in neuronal lipid rafts

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3 June 2018

MAPK recruitment by beta-amyloid in organotypic hippocampal slice cultures depends on physical state and exposure time

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3 June 2018

The roles of MAPK cascades in synaptic plasticity and memory in Aplysia: facilitatory effects and inhibitory constraints

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3 June 2018

MAPK activation in nociceptive neurons and pain hypersensitivity

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3 June 2018

Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells

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3 June 2018

JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated Proteins

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3 June 2018

Unfolding the role of protein misfolding in neurodegenerative diseases

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3 June 2018

p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells

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3 June 2018

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

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3 June 2018

alpha-Synuclein affects the MAPK pathway and accelerates cell death

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3 June 2018

Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiation

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3 June 2018

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3 June 2018

Sustained MAP kinase activation is required for the expression of cyclin D1, p21Cip1 and a subset of AP-1 proteins in CCL39 cells

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3 June 2018

The repertoire of fos and jun proteins expressed during the G1 phase of the cell cycle is determined by the duration of mitogen-activated protein kinase activation

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3 June 2018

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3 June 2018

The transcription factor E2F-1 is a downstream target of RB action

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3 June 2018

Synthesis and trafficking of prion proteins in cultured cells

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3 June 2018

JNK3 is abundant in insulin-secreting cells and protects against cytokine-induced apoptosis

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21 January 2018

Mitogen-activated protein kinase phosphatase 1 negatively regulates MAPK signaling in mouse hypothalamus

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21 January 2018

Activation of the JNK-c-Jun pathway during the early phase of neuronal apoptosis induced by PrP106-126 and prion infection.

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21 January 2018

Minocycline attenuates Aβ oligomers-induced pro-inflammatory phenotype in primary microglia while enhancing Aβ fibrils phagocytosis.

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21 January 2018

The release of calcium from the endoplasmic reticulum induced by amyloid-beta and prion peptides activates the mitochondrial apoptotic pathway.

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21 January 2018

An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity.

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21 January 2018

Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK), stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38 kinase expression in Parkinson's disease and Dementia with Lewy bodies.

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21 January 2018

Repeated intra-hippocampal injection of beta-amyloid 25–35 induces a reproducible impairment of learning and memory: considering caspase-3 and MAPKs activity.

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21 January 2018

Inhibition of p38 pathway-dependent MPTP-induced dopaminergic neurodegeneration in estrogen receptor alpha knockout mice

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21 January 2018

Activation of mitogen-activated protein kinases in hamster brains infected with 263K scrapie agent

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21 January 2018

Ozone (O3) elicits neurotoxicity in spinal cord neurons (SCNs) by inducing ER Ca(2+) release and activating the CaMKII/MAPK signaling pathway.

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https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

The 5-HT7 receptor triggers cerebellar long-term synaptic depression via PKC-MAPK.

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

Protective effects of the p38 MAPK inhibitor SB203580 on NMDA‑induced injury in primary cerebral cortical neurons

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

Clustering of cellular prion protein induces ERK1/2 and stathmin phosphorylation in GT1-7 neuronal cells.

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

Rutin ameliorates cyclophosphamide induced oxidative stress and inflammation in Wistar rats: role of NFκB/MAPK pathway

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

FK506 reduces abnormal prion protein through the activation of autolysosomal degradation and prolongs survival in prion-infected mice.

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

Role of p38 and inducible nitric oxide synthase in the in vivo dopaminergic cells' degeneration induced by inflammatory processes after lipopolysaccharide injection

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

P38 MAP kinase is activated at early stages in Alzheimer's disease brain

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

In vitro self-propagation of recombinant PrPSc-like conformation generated in the yeast cytoplasm

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

Neuroprotective effect of berberine is mediated by MAPK signaling pathway in experimental diabetic neuropathy in rats

1 reference

https://api.crossref.org/works/10.3389%2FFNAGI.2017.00120

21 January 2018

Bcl-2 overexpression protects against amyloid-beta and prion toxicity in GT1-7 neural cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5410568

26 November 2018

Cellular tolerance of prion protein PrP in yeast involves proteolysis and the unfolded protein response

1 reference

https://pubmed.ncbi.nlm.nih.gov/28507517

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated glia induce neuron death via MAP kinase signaling pathways involving JNK and p38

1 reference

https://pubmed.ncbi.nlm.nih.gov/28507517

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3389/FNAGI.2017.00120

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507517%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507517%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507517%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

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