Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex (Q28569612)

31 January 2017

title

Munc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complex (English)

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31 January 2017

Josep Rizo

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31 January 2017

Cong Ma

1 reference

31 January 2017

Wei Li

series ordinal

1 reference

31 January 2017

Yibin Xu

series ordinal

1 reference

31 January 2017

publication date

1 May 2011

1 reference

Nature Structural & Molecular Biology

31 January 2017

published in

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31 January 2017

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31 January 2017

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31 January 2017

page(s)

542–549

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NMR View: A computer program for the visualization and analysis of NMR data

31 January 2017

cites work

1 reference

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Single-Vesicle Fusion Assay Reveals Munc18-1 Binding to the SNARE Core Is Sufficient for Stimulating Membrane Fusion

19 March 2017

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A Structure-Based Mechanism for Vesicle Capture by the Multisubunit Tethering Complex Dsl1

19 March 2017

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A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1

19 March 2017

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Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming

19 March 2017

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Membrane fusion: grappling with SNARE and SM proteins

19 March 2017

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Conformational switch of syntaxin-1 controls synaptic vesicle fusion

19 March 2017

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Munc18a controls SNARE assembly through its interaction with the syntaxin N-peptide

19 March 2017

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Binding of the Munc13-1 MUN domain to membrane-anchored SNARE complexes

19 March 2017

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Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminus

19 March 2017

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Munc18-1 binds directly to the neuronal SNARE complex

19 March 2017

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Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release

19 March 2017

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Structural basis for a Munc13-1 homodimer to Munc13-1/RIM heterodimer switch

19 March 2017

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A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?

19 March 2017

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The synaptic vesicle cycle

19 March 2017

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Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming

19 March 2017

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Three-dimensional structure of the complexin/SNARE complex

19 March 2017

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RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone

19 March 2017

1 reference

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Functional interaction of the active zone proteins Munc13-1 and RIM1 in synaptic vesicle priming

19 March 2017

1 reference

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Three-dimensional structure of the neuronal-Sec1-syntaxin 1a complex

19 March 2017

1 reference

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Drosophila UNC-13 is essential for synaptic transmission

19 March 2017

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A conformational switch in syntaxin during exocytosis: role of munc18.

19 March 2017

1 reference

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Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles

19 March 2017

1 reference

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Crystal structure of a SNARE complex involved in synaptic exocytosis at 2.4 A resolution

19 March 2017

1 reference

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Three-dimensional structure of an evolutionarily conserved N-terminal domain of syntaxin 1A

19 March 2017

1 reference

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Structure and conformational changes in NSF and its membrane receptor complexes visualized by quick-freeze/deep-etch electron microscopy

19 March 2017

1 reference

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Direct interaction of the rat unc-13 homologue Munc13-1 with the N terminus of syntaxin

19 March 2017

1 reference

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NMRPipe: a multidimensional spectral processing system based on UNIX pipes

19 March 2017

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Mammalian homologues of Caenorhabditis elegans unc-13 gene define novel family of C2-domain proteins

19 March 2017

1 reference

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SNAREs--engines for membrane fusion

19 March 2017

1 reference

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Synaptic assembly of the brain in the absence of neurotransmitter secretion

7 April 2017

1 reference

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SNARE bundle and syntaxin N-peptide constitute a minimal complement for Munc18-1 activation of membrane fusion.

7 April 2017

1 reference

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At the junction of SNARE and SM protein function

29 September 2017

1 reference

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Binding of the complexin N terminus to the SNARE complex potentiates synaptic-vesicle fusogenicity.

29 September 2017

1 reference

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Binding of Munc18-1 to synaptobrevin and to the SNARE four-helix bundle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

CAPS drives trans-SNARE complex formation and membrane fusion through syntaxin interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Methyl groups as probes of supra-molecular structure, dynamics and function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

The Janus-faced nature of the C(2)B domain is fundamental for synaptotagmin-1 function.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

29 September 2017

Synaptic vesicle fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Accessory proteins stabilize the acceptor complex for synaptobrevin, the 1:1 syntaxin/SNAP-25 complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Munc18-1 prevents the formation of ectopic SNARE complexes in living cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Unraveling the mechanisms of synaptotagmin and SNARE function in neurotransmitter release

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Structure and function of SNARE and SNARE-interacting proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

UNC-13 interaction with syntaxin is required for synaptic transmission.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Two distinct secretory vesicle-priming steps in adrenal chromaffin cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Synaptobrevin N-terminally bound to syntaxin-SNAP-25 defines the primed vesicle state in regulated exocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

NMR analysis of the closed conformation of syntaxin-1.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

A quaternary SNARE-synaptotagmin-Ca2+-phospholipid complex in neurotransmitter release

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

Selective activation of cognate SNAREpins by Sec1/Munc18 proteins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

A post-docking role for active zone protein Rim.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3087822

The synaptic SNARE complex is a parallel four-stranded helical bundle

3 June 2018

1 reference

UNC-13 is required for synaptic vesicle fusion in C. elegans

21 January 2018

1 reference

Identification of the minimal protein domain required for priming activity of Munc13-1.

21 January 2018

1 reference

A minimal domain responsible for Munc13 activity

21 January 2018

1 reference

SNARE assembly and disassembly exhibit a pronounced hysteresis

21 January 2018

1 reference

Remote homology between Munc13 MUN domain and vesicle tethering complexes

21 January 2018

1 reference

Line narrowing in methyl-TROSY using zero-quantum 1H-13C NMR spectroscopy

21 January 2018

1 reference

Facile detection of protein-protein interactions by one-dimensional NMR spectroscopy

21 January 2018

1 reference

31 March 2020

Identifiers

DOI

10.1038/NSMB.2047

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1 reference

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