Constitutive activation of IkappaB kinase alpha and NF-kappaB in prostate cancer cells is inhibited by ibuprofen (Q28377754)

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S K Calderwood

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C N Coleman

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B D Price

bcl-2 overexpression combined with p53 protein accumulation correlates with hormone-refractory prostate cancer

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language of work or name

English

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publication date

2 December 1999

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7389-94

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cites work

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NF-kappa B: ten years after

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The DNA-dependent protein kinase participates in the activation of NF kappa B following DNA damage

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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IKAP is a scaffold protein of the IkappaB kinase complex

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Bcl-2 activates the transcription factor NFkappaB through the degradation of the cytoplasmic inhibitor IkappaBalpha

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7 January 2021

Yes, but do they still get headaches?

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Inhibition of NF-kappa B by sodium salicylate and aspirin

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Molecular mechanisms of constitutive NF-kappaB/Rel activation in Hodgkin/Reed-Sternberg cells.

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The correlation between blood levels of ibuprofen and clinical analgesic response

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MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

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NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

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TNF-mediated cytotoxicity and resistance in human prostate cancer cell lines

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Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

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Mutual transcriptional interference between RelA and androgen receptor

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Overexpression of RelA in transgenic mouse thymocytes: specific increase in levels of the inhibitor protein I kappa B alpha

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Reciprocal effects of pro-inflammatory stimuli and anti-inflammatory drugs on the activity of heat shock factor-1 in human monocytes

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NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

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Nuclear factor kappa B functions as a negative regulator for the rat androgen receptor gene and NF-kappa B activity increases during the age-dependent desensitization of the liver

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7 January 2021

Phosphorylation of human I kappa B-alpha on serines 32 and 36 controls I kappa B-alpha proteolysis and NF-kappa B activation in response to diverse stimuli

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7 January 2021

TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

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IEX-1L, an apoptosis inhibitor involved in NF-kappaB-mediated cell survival

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The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

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Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

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