Disruption of the Diaphanous-related formin Drf1 gene encoding mDia1 reveals a role for Drf3 as an effector for Cdc42 (Q28188673)

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Bradley J Wallar

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Akiko Flanders

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Pamela J Swiatek

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Arthur S Alberts

FH proteins as cytoskeletal organizers

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language of work or name

English

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publication date

1 April 2003

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534-45

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cites work

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Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis

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7 January 2021

p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

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Rho1p-Bni1p-Spa2p interactions: implication in localization of Bni1p at the bud site and regulation of the actin cytoskeleton in Saccharomyces cerevisiae

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7 January 2021

Roles of the fission yeast formin for3p in cell polarity, actin cable formation and symmetric cell division

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7 January 2021

Nonsyndromic deafness DFNA1 associated with mutation of a human homolog of the Drosophila gene diaphanous

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A human homologue of the Drosophila melanogaster diaphanous gene is disrupted in a patient with premature ovarian failure: evidence for conserved function in oogenesis and implications for human sterility

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7 January 2021

Analysis of RhoA-binding proteins reveals an interaction domain conserved in heterotrimeric G protein beta subunits and the yeast response regulator protein Skn7

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7 January 2021

Cooperation between mDia1 and ROCK in Rho-induced actin reorganization

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Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain

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7 January 2021

Distinct actions and cooperative roles of ROCK and mDia in Rho small G protein-induced reorganization of the actin cytoskeleton in Madin-Darby canine kidney cells

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7 January 2021

mDia mediates Rho-regulated formation and orientation of stable microtubules

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7 January 2021

Rho GTPases and the actin cytoskeleton

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Dynamic localization and function of Bni1p at the sites of directed growth in Saccharomyces cerevisiae

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Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction

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7 January 2021

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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7 January 2021

WIP regulates N-WASP-mediated actin polymerization and filopodium formation

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Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

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7 January 2021

Cellular control of actin nucleation

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N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

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Cdc42 induces filopodia by promoting the formation of an IRSp53:Mena complex

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7 January 2021

Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility

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7 January 2021

Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2

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7 January 2021

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

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A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

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7 January 2021

Multiple sequence alignment with Clustal X

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Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

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GFP imaging: methodology and application to investigate cellular compartmentation in plants

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Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKCzeta

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Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization

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7 January 2021

Interaction of Rho1p target Bni1p with F-actin-binding elongation factor 1alpha: implication in Rho1p-regulated reorganization of the actin cytoskeleton in Saccharomyces cerevisiae

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7 January 2021

The diaphanous-related formin mDia1 controls serum response factor activity through its effects on actin polymerization

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7 January 2021

An actin nucleation mechanism mediated by Bni1 and profilin

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7 January 2021

Role of formins in actin assembly: nucleation and barbed-end association

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7 January 2021

Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity

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7 January 2021

mDia-interacting protein acts downstream of Rho-mDia and modifies Src activation and stress fiber formation

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7 January 2021

Nerve growth cone lamellipodia contain two populations of actin filaments that differ in organization and polarity

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7 January 2021

Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone

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7 January 2021

Effect of capping protein on the kinetics of actin polymerization.

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7 January 2021

The formin/diaphanous-related protein, FHOS, interacts with Rac1 and activates transcription from the serum response element

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7 January 2021

Srf(-/-) ES cells display non-cell-autonomous impairment in mesodermal differentiation

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7 January 2021

Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells

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7 January 2021

A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42

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7 January 2021