The two faces of miR-29 (Q26996481)

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Language	Label	Description	Also known as
English	The two faces of miR-29	scientific article

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scholarly article

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Europe PubMed Central

The two faces of miR-29 (English)

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author name string

Anna Ślusarz

1

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Lakshmi Pulakat

2

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language of work or name

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publication date

July 2015

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Journal of Cardiovascular Medicine

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16

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7

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480-90

1 reference

Small molecules, big effects: the role of microRNAs in regulation of cardiomyocyte death

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21 March 2017

Identification of novel targets for miR-29a using miRNA proteomics

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21 March 2017

mTOR signaling in growth control and disease

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21 March 2017

Inhibition of microRNA-29b reduces murine abdominal aortic aneurysm development

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21 March 2017

Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia

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21 March 2017

MCL-1ES, a novel variant of MCL-1, associates with MCL-1L and induces mitochondrial cell death

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Widespread microRNA repression by Myc contributes to tumorigenesis

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21 March 2017

MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B

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21 March 2017

mir-29 regulates Mcl-1 protein expression and apoptosis

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21 March 2017

Human MicroRNA targets

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MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain

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21 March 2017

High glucose down-regulates miR-29a to increase collagen IV production in HK-2 cells

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Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181

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21 March 2017

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c

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21 March 2017

Regulation of cardiac expression of the diabetic marker microRNA miR-29

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21 March 2017

MicroRNA miR-29c down-regulation leading to de-repression of its target DNA methyltransferase 3a promotes ischemic brain damage

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21 March 2017

The orphan receptor TR3 participates in angiotensin II-induced cardiac hypertrophy by controlling mTOR signalling

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21 March 2017

FKBP12.6 disruption impairs glucose-induced insulin secretion

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21 March 2017

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

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7 April 2017

Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis

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7 April 2017

Atherosclerosis-related circulating miRNAs as novel and sensitive predictors for acute myocardial infarction

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28 September 2017

MiRiad Roles for MicroRNAs in Cardiac Development and Regeneration

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28 September 2017

Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers

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28 September 2017

MicroRNAs in diabetic cardiomyopathy and clinical perspectives

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28 September 2017

c-Myc suppresses microRNA-29b to promote tumor aggressiveness and poor outcomes in non-small cell lung cancer by targeting FHIT.

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28 September 2017

MicroRNA-29 fine-tunes the expression of key FOXA2-activated lipid metabolism genes and is dysregulated in animal models of insulin resistance and diabetes.

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28 September 2017

Linagliptin-mediated DPP-4 inhibition ameliorates kidney fibrosis in streptozotocin-induced diabetic mice by inhibiting endothelial-to-mesenchymal transition in a therapeutic regimen

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28 September 2017

miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling

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28 September 2017

Modulation of the pancreatic islet-stress axis as a novel potential therapeutic target in diabetes mellitus

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28 September 2017

Mammalian target of rapamycin signaling in cardiac physiology and disease.

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28 September 2017

Atrial fibrillation and microRNAs

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28 September 2017

Urinary miR-29 correlates with albuminuria and carotid intima-media thickness in type 2 diabetes patients

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 September 2017

The many faces of diabetes: a disease with increasing heterogeneity

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28 September 2017

miR-29b, miR-205 and miR-221 enhance chemosensitivity to gemcitabine in HuH28 human cholangiocarcinoma cells

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28 September 2017

Tailoring mTOR-based therapy: molecular evidence and clinical challenges

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28 September 2017

The increasing detection of asymptomatic left ventricular dysfunction in patients with type 2 diabetes mellitus without overt cardiac disease: data from the SHORTWAVE study

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28 September 2017

Evidence for rapamycin toxicity in pancreatic β-cells and a review of the underlying molecular mechanisms.

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28 September 2017

MicroRNA-29b regulation of abdominal aortic aneurysm development

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 September 2017

Mechanism of miRNA-mediated repression of mRNA translation.

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28 September 2017

Intestinal Salmonella typhimurium infection leads to miR-29a induced caveolin 2 regulation

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28 September 2017

Adipose tissue inflammation: feeding the development of type 2 diabetes mellitus

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28 September 2017

Deletion of MCL-1 causes lethal cardiac failure and mitochondrial dysfunction

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28 September 2017

MicroRNA-containing microvesicles regulating inflammation in association with atherosclerotic disease.

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28 September 2017

Obesity-associated low-grade inflammation in type 2 diabetes mellitus: causes and consequences

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28 September 2017

Management of the patient with diabetes and coronary artery disease: a contemporary review

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28 September 2017

Circulating microRNAs as novel biomarkers for diabetes mellitus

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28 September 2017

Therapeutic Delivery of MicroRNA-29b by Cationic Lipoplexes for Lung Cancer

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28 September 2017

Improving diabetes management with mobile health technology

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28 September 2017

MicroRNA29: a mechanistic contributor and potential biomarker in atrial fibrillation

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28 September 2017

The multiple origins of Type 1 diabetes

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28 September 2017

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma.

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28 September 2017

Cardiovascular risk factors in a patient with diabetes mellitus and coronary artery disease: therapeutic approaches to improve outcomes: perspectives of a preventive cardiologist

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28 September 2017

Acute coronary syndrome in patients with diabetes mellitus: perspectives of an interventional cardiologist

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28 September 2017

Regulation of Overnutrition-Induced Cardiac Inflammatory Mechanisms

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28 September 2017

MicroRNA-29a is up-regulated in beta-cells by glucose and decreases glucose-stimulated insulin secretion

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28 September 2017

MiRNA-29: a microRNA family with tumor-suppressing and immune-modulating properties

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28 September 2017

Circulating levels of microRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression.

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28 September 2017

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28 September 2017

Changes in microRNA expression contribute to pancreatic β-cell dysfunction in prediabetic NOD mice

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28 September 2017

Cardiovascular risk in double diabetes mellitus--when two worlds collide

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28 September 2017

MicroRNAs in metabolism and metabolic disorders

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28 September 2017

Circulating microRNAs: novel biomarkers and extracellular communicators in cardiovascular disease?

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28 September 2017

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28 September 2017

Inhibition of microRNA-29 enhances elastin levels in cells haploinsufficient for elastin and in bioengineered vessels--brief report

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28 September 2017

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28 September 2017

Cardiac insulin resistance and microRNA modulators

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28 September 2017

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28 September 2017

Adaptive mechanisms to compensate for overnutrition-induced cardiovascular abnormalities

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28 September 2017

miR-29a and miR-29b contribute to pancreatic beta-cell-specific silencing of monocarboxylate transporter 1 (Mct1)

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28 September 2017

MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy

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28 September 2017

MicroRNAs differentially expressed in postnatal aortic development downregulate elastin via 3' UTR and coding-sequence binding sites

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28 September 2017

Mammalian target of rapamycin (mTOR) inhibitors: potential uses and a review of haematological adverse effects

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28 September 2017

miR-29 is a major regulator of genes associated with pulmonary fibrosis.

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28 September 2017

Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis

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28 September 2017

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28 September 2017

Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes

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28 September 2017

MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice

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28 September 2017

The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML.

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28 September 2017

Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB.

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28 September 2017

miR-29 modulates Wnt signaling in human osteoblasts through a positive feedback loop.

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28 September 2017

Mcl-1; the molecular regulation of protein function

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28 September 2017

Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue

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28 September 2017

Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischaemia-reperfusion injury

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28 September 2017

miR-29 suppression of osteonectin in osteoblasts: regulation during differentiation and by canonical Wnt signaling

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28 September 2017

Sex-different and growth hormone-regulated expression of microRNA in rat liver

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28 September 2017

Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cells

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28 September 2017

Mcl-1 is a potential therapeutic target in multiple types of cancer

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28 September 2017

Sirolimus is associated with new-onset diabetes in kidney transplant recipients.

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28 September 2017

Antiproliferative effect of rapamycin on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomerase inhibition

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28 September 2017

Sirolimus-eluting coronary stents: a review

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28 September 2017

Glucose phosphorylation is required for insulin-dependent mTOR signalling in the heart

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28 September 2017

The heterogeneity of diabetes: unraveling a dispute: is systemic inflammation related to islet autoimmunity?

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28 September 2017

Diabetes mellitus and heart failure: epidemiology, mechanisms, and pharmacotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 September 2017

Metabolic syndrome and risk of cardiovascular disease: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 September 2017

RegRNA: an integrated web server for identifying regulatory RNA motifs and elements

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 September 2017

Diabetic cardiomyopathy: the search for a unifying hypothesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 September 2017

Rapamycin: an anti-cancer immunosuppressant?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 September 2017

Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 September 2017

miR-29 acts as a decoy in sarcomas to protect the tumor suppressor A20 mRNA from degradation by HuR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

31 May 2018

Loss of MCL-1 leads to impaired autophagy and rapid development of heart failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

31 May 2018

Overexpression of micro ribonucleic acid 29, highly up-regulated in diabetic rats, leads to insulin resistance in 3T3-L1 adipocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

31 May 2018

Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

31 May 2018

The Diabetic Zucker Fatty Rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

31 May 2018

The microRNA-132/212 family fine-tunes multiple targets in Angiotensin II signalling in cardiac fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

MicroRNA-29a-c decrease fasting blood glucose levels by negatively regulating hepatic gluconeogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

miR-29b participates in early aneurysm development in Marfan syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Cardiac raptor ablation impairs adaptive hypertrophy, alters metabolic gene expression, and causes heart failure in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Rapamycin impairs proliferation of transplanted islet β cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

miR-29a levels are elevated in the db/db mice liver and its overexpression leads to attenuation of insulin action on PEPCK gene expression in HepG2 cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Long-term administration of rapamycin reduces adiposity, but impairs glucose tolerance in high-fat diet-fed KK/HlJ mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Low-grade inflammation can partly explain the association between the metabolic syndrome and either coronary artery disease or severity of peripheral arterial disease: the CODAM study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Conversion to sirolimus in kidney-pancreas and pancreas transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Rapamycin impairs beta-cell proliferation in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Rapamycin impairs in vivo proliferation of islet beta-cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Sirolimus and cardiac transplantation: is it the "magic bullet"?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Low grade inflammation in juvenile obesity and type 1 diabetes associated with early signs of atherosclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4449311

28 November 2018

The effects of immunosuppressants on vascular function, systemic oxidative stress and inflammation in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25689084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Krüppel-like factor 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/25689084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compensatory recovery of blood glucose levels in KKA(y) mice fed a high-fat diet: insulin-sparing effects of PACAP overexpression in β cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25689084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirolimus therapy predisposes to new-onset diabetes mellitus after renal transplantation: a long-term analysis of various treatment regimens

1 reference

https://pubmed.ncbi.nlm.nih.gov/25689084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New insights into microRNA-29 regulation: a new key player in cardiovascular disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/25689084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The double-faced metabolic and inflammatory effects of standard drug therapy in patients after percutaneous treatment with drug-eluting stent

1 reference

https://pubmed.ncbi.nlm.nih.gov/25689084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Myocardial hypertrophy and enhanced left ventricular contractility in Zucker diabetic fatty rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25689084

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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