FoxL2 and Smad3 coordinately regulate follistatin gene transcription (Q24655444)

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Nicholas J Justice

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Wylie W Vale

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Wolfgang H Fischer

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Louise M Bilezikjian

Journal of Biological Chemistry

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language of work or name

English

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publication date

20 March 2009

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published in

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volume

284

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issue

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page(s)

7631-45

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cites work

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Transcription activation of FLRG and follistatin by activin A, through Smad proteins, participates in a negative feedback loop to modulate activin A function

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Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in natural killer cell-depleted SCID mice

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A Smad-binding element in intron 1 participates in activin-dependent regulation of the follistatin gene

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The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance

7 April 2017

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The gonadotropin releasing hormone (GnRH) receptor activating sequence (GRAS) is a composite regulatory element that interacts with multiple classes of transcription factors including Smads, AP-1 and a forkhead DNA binding protein

7 April 2017

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7 April 2017

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Spectrum of FOXL2 gene mutations in blepharophimosis-ptosis-epicanthus inversus (BPES) families demonstrates a genotype--phenotype correlation

7 April 2017

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Follistatin: a multifunctional regulatory protein

7 April 2017

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Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

7 April 2017

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Smad4 and FAST-1 in the assembly of activin-responsive factor

7 April 2017

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Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development

7 April 2017

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7 April 2017

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Follistatin gene expression in the ovary and extragonadal tissues

7 April 2017

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7 April 2017

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7 April 2017

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Proteomic analysis of conditioned media from the PC3, LNCaP, and 22Rv1 prostate cancer cell lines: discovery and validation of candidate prostate cancer biomarkers

7 April 2017

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FOXL2 in the pituitary: molecular, genetic, and developmental analysis

28 September 2017

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Foxl2 function in ovarian development.

28 September 2017

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28 September 2017

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Autocrine/paracrine regulation of pituitary function by activin, inhibin and follistatin

28 September 2017

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28 September 2017

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Rat anterior pituitary folliculostellate cells are targets of interleukin-1beta and a major source of intrapituitary follistatin

28 September 2017

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28 September 2017

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28 September 2017

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Pituitary activin receptor subtypes and follistatin gene expression in female rats: differential regulation by activin and follistatin

28 September 2017

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Primary structure of the human follistatin precursor and its genomic organization

28 September 2017

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Structural characterization of follistatin: a novel follicle-stimulating hormone release-inhibiting polypeptide from the gonad

28 September 2017

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Follistatin binds to both activin and inhibin through the common subunit

28 September 2017

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Follistatin gene expression in the pituitary: localization in gonadotropes and folliculostellate cells in diestrous rats

28 September 2017

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Multiple defects and perinatal death in mice deficient in follistatin

28 September 2017

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28 September 2017

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30 May 2018

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Increased follistatin (activin-binding protein) gene expression in rat anterior pituitary tissue after ovariectomy may be mediated by pituitary activin

30 May 2018

1 reference

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Molecular heterogeneity of follistatin, an activin-binding protein. Higher affinity of the carboxyl-terminal truncated forms for heparan sulfate proteoglycans on the ovarian granulosa cell

30 May 2018

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Activin-binding protein from rat ovary is follistatin

30 May 2018

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Evidence for an autocrine role of activin B within rat anterior pituitary cultures

30 May 2018

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Activin-binding protein is present in pituitary

30 May 2018

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Immunohistochemical Localization of Follistatin in Rat Tissues

30 May 2018

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Intracellular Responses to Gonadotropin-Releasing Hormone in a Clonal Cell Line of the Gonadotrope Lineage

30 May 2018

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Regulation of steady-state follistatin mRNA levels in rat granulosa cells in vitro

30 May 2018

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Identification of 34 novel and 56 known FOXL2 mutations in patients with Blepharophimosis syndrome.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658057

Differential functional effects of novel mutations of the transcription factor FOXL2 in BPES patients

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658057

Design and cloning of lentiviral vectors expressing small interfering RNAs

28 November 2018

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28 November 2018

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Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658057

Evidence that pituitary adenylate cyclase activating polypeptide suppresses follicle-stimulating hormone-beta messenger ribonucleic acid levels by stimulating follistatin gene transcription

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2658057

Activin-A regulates follistatin secretion from cultured rat anterior pituitary cells

28 November 2018

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Activin effects on neoplastic proliferation of human pituitary tumors

28 November 2018

1 reference

PubMed

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The isolation of polypeptides with FSH suppressing activity from bovine follicular fluid which are structurally different to inhibin

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19106105

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Gonadotropin-releasing hormone regulates follicle-stimulating hormone-beta gene expression through an activin/follistatin autocrine or paracrine loop

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19106105