Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex (Q24629899)

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English	Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex	scientific article

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scholarly article

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Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex (English)

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drug resistance

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Enoch P Baldwin

4

object named as

Enoch P Baldwin

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author name string

James A Endrizzi

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Hanseong Kim

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Paul M Anderson

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Enoch P Baldwin

4

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language of work or name

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publication date

18 October 2005

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44

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41

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13491-9

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1 reference

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Crystal structure of Escherichia coli cytidine triphosphate synthetase, a nucleotide-regulated glutamine amidotransferase/ATP-dependent amidoligase fusion protein and homologue of anticancer and antiparasitic drug targets

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Mammalian mutants genetically altered in CTP synthetase activity.

1 reference

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30 May 2018

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1 reference

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CTP synthetase of bovine calf liver

1 reference

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Alternative IMP binding in feedback inhibition of hypoxanthine-guanine phosphoribosyltransferase from Thermoanaerobacter tengcongensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2891682

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1 reference

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1 reference

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1 reference

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28 November 2018

Nucleotide-dependent tetramerization of CTP synthetase from Saccharomyces cerevisiae

1 reference

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28 November 2018

Cyclopentenyluridine and cyclopentenylcytidine analogs as inhibitors of uridine-cytidine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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based on heuristic

inferred from PubMed ID database lookup

Role of an allosteric effector. Guanosine triphosphate activation in cytosine triphosphate synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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based on heuristic

inferred from PubMed ID database lookup

Substrate specificity of CTP synthetase from Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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based on heuristic

inferred from PubMed ID database lookup

Cytidine 5'-triphosphate synthetase as a target for inhibition by the antitumor agent 3-deazauridine

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies on the antitumor activity and biochemical actions of cyclopentenyl cytosine against human colon carcinoma HT-29 in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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based on heuristic

inferred from PubMed ID database lookup

Cytidine triphosphate synthetase of Escherichia coli B. I. Purification and kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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based on heuristic

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CTP synthetase from Ehrlich ascites tumor cells. Subunit stoichiometry and regulation of activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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based on heuristic

inferred from PubMed ID database lookup

TNT refinement package

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of glutamine in the biosynthesis of cytidine nucleotides in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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Ligand-induced dimer-to-tetramer transformation in cytosine triphosphate synthetase

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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based on heuristic

inferred from PubMed ID database lookup

In situ regulation of mammalian CTP synthetase by allosteric inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/16216072

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based on heuristic

inferred from PubMed ID database lookup

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10.1021/BI051282O

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