FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development (Q24321511)

positive regulation of transcription by RNA polymerase II

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Harold E Varmus

0 references

Ali Hemmati-Brivanlou

object named as

Ali H Brivanlou

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author name string

Mario N Chamorro

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Donald R Schwartz

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Alin Vonica

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Kathleen R Cho

Wnt11 signaling promotes proliferation, transformation, and migration of IEC6 intestinal epithelial cells

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language of work or name

English

0 references

publication date

12 January 2005

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73-84

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cites work

1 reference

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The beta-catenin/TCF-4 complex imposes a crypt progenitor phenotype on colorectal cancer cells

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Nr-CAM is a target gene of the beta-catenin/LEF-1 pathway in melanoma and colon cancer and its expression enhances motility and confers tumorigenesis

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A transcriptional response to Wnt protein in human embryonic carcinoma cells

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Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling

19 March 2017

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Use of chromatin immunoprecipitation to clone novel E2F target promoters

19 March 2017

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Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

19 March 2017

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Tyrosine kinase signalling in breast cancer: fibroblast growth factors and their receptors

19 March 2017

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Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein

19 March 2017

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Identification of c-MYC as a target of the APC pathway

19 March 2017

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A beta-catenin/XTcf-3 complex binds to the siamois promoter to regulate dorsal axis specification in Xenopus

19 March 2017

1 reference

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Association of the APC gene product with beta-catenin

19 March 2017

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Loss of Apc heterozygosity and abnormal tissue building in nascent intestinal polyps in mice carrying a truncated Apc gene

19 March 2017

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A system for stable expression of short interfering RNAs in mammalian cells

19 March 2017

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19 March 2017

Wnt signaling and cancer

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Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

19 March 2017

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Identification of a novel human fibroblast growth factor and characterization of its role in oncogenesis

19 March 2017

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The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

19 March 2017

1 reference

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LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

19 March 2017

1 reference

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FGF4, a direct target of LEF1 and Wnt signaling, can rescue the arrest of tooth organogenesis in Lef1(-/-) mice

19 March 2017

1 reference

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Naked cuticle targets dishevelled to antagonize Wnt signal transduction

19 March 2017

1 reference

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Fibroblast growth factors, their receptors and signaling

19 March 2017

1 reference

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Characterization of a novel member of the FGF family, XFGF-20, in Xenopus laevis

19 March 2017

1 reference

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Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

19 March 2017

1 reference

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Regulation of Wnt signaling by Sox proteins: XSox17 alpha/beta and XSox3 physically interact with beta-catenin

19 March 2017

1 reference

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Secreted antagonists of the Wnt signalling pathway

19 March 2017

1 reference

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Linking colorectal cancer to Wnt signaling

7 April 2017

1 reference

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Wnt signaling in oncogenesis and embryogenesis--a look outside the nucleus

7 April 2017

1 reference

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

7 April 2017

1 reference

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Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

7 April 2017

1 reference

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Regulation of intracellular beta-catenin levels by the adenomatous polyposis coli (APC) tumor-suppressor protein

7 April 2017

1 reference

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Wnt target genes identified by DNA microarrays in immature CD34+ thymocytes regulate proliferation and cell adhesion.

7 April 2017

1 reference

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Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex

27 September 2017

1 reference

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A role for maternal beta-catenin in early mesoderm induction in Xenopus.

27 September 2017

1 reference

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Novel candidate targets of beta-catenin/T-cell factor signaling identified by gene expression profiling of ovarian endometrioid adenocarcinomas.

27 September 2017

1 reference

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Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

27 September 2017

1 reference

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The Wnt signalling pathway

27 September 2017

1 reference

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The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Silencing of Wnt signaling and activation of multiple metabolic pathways in response to thyroid hormone-stimulated cell proliferation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

New aspects of Wnt signaling pathways in higher vertebrates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Curbing the nuclear activities of beta-catenin. Control over Wnt target gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Neural crest-directed gene transfer demonstrates Wnt1 role in melanocyte expansion and differentiation during mouse development.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Mapping chromosomal proteins in vivo by formaldehyde-crosslinked-chromatin immunoprecipitation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Mesoderm induction in Xenopus is a zygotic event regulated by maternal VegT via TGFbeta growth factors.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Development of a flexible and specific gene delivery system for production of murine tumor models

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

The EV-O-derived cell line DF-1 supports the efficient replication of avian leukosis-sarcoma viruses and vectors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

The DF-1 chicken fibroblast cell line: transformation induced by diverse oncogenes and cell death resulting from infection by avian leukosis viruses

27 September 2017

1 reference

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Siamois is required for formation of Spemann's organizer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Expression of a dominant-negative Wnt blocks induction of MyoD in Xenopus embryos

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

eFGF regulates Xbra expression during Xenopus gastrulation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Xwnt-8, a Xenopus Wnt-1/int-1-related gene responsive to mesoderm-inducing growth factors, may play a role in ventral mesodermal patterning during embryogenesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Expression of a xenopus homolog of Brachyury (T) is an immediate-early response to mesoderm induction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Formation and function of Spemann's organizer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

30 May 2018

1 reference

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Characterization of a human colonic adenocarcinoma cell line, LS123.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

A mouse model for glioma: biology, pathology, and therapeutic opportunities.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Zygotic Wnt activity is required for Brachyury expression in the early Xenopus laevis embryo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Diverse mechanisms of beta-catenin deregulation in ovarian endometrioid adenocarcinomas.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Difference in XTcf-3 dependency accounts for change in response to beta-catenin-mediated Wnt signalling in Xenopus blastula.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Region-specific activation of the Xenopus brachyury promoter involves active repression in ectoderm and endoderm: a study using transgenic frog embryos.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

TCF is the nuclear effector of the beta-catenin signal that patterns the sea urchin animal-vegetal axis.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

Chromosomal translocations and leukaemia: a role for LMO2 in T cell acute leukaemia, in transcription and in erythropoiesis

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=544900

The homeobox gene Siamois is a target of the Wnt dorsalisation pathway and triggers organiser activity in the absence of mesoderm

29 November 2018

1 reference

12 December 2020

Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor

1 reference

12 December 2020

Axis induction by wnt signaling: Target promoter responsiveness regulates competence

1 reference

12 December 2020

Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated beta-catenin

1 reference

12 December 2020

Cyclin D1 is not an essential target of beta-catenin signaling during intestinal tumorigenesis, but it may act as a modifier of disease severity in multiple intestinal neoplasia (Min) mice

1 reference

12 December 2020

Injected Xwnt-8 RNA acts early in Xenopus embryos to promote formation of a vegetal dorsalizing center

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600460

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/SJ.EMBOJ.7600460

1 reference

1 reference

1 reference

PubMed publication ID

15592430

1 reference