MIF signal transduction initiated by binding to CD74 (Q24303802)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0035691

macrophage migration inhibitory factor receptor complex

1 reference

Gene Ontology release 2020-05-02

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Macrophage migration inhibitory factor

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positive regulation of ERK1 and ERK2 cascade

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CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

1 reference

Richard Bucala

Richard

Bucala

1 reference

ORCID Public Data File 2021

19 October 2023

1 reference

Lin Leng

Lin

Leng

1 reference

19 October 2023

Christine N Metz

0 references

Yan Fang

Yan

Fang

1 reference

19 October 2023

Jing Xu

Jing

1 reference

19 October 2023

Seamas Donnelly

Seamas

Donnelly

1 reference

19 October 2023

John Baugh

John

Baugh

1 reference

19 October 2023

Thomas Delohery

Thomas

Delohery

1 reference

19 October 2023

Yibang Chen

Yibang

Chen

1 reference

19 October 2023

Robert A Mitchell

Robert A

Mitchell

1 reference

Journal of Experimental Medicine

19 October 2023

language of work or name

English

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publication date

2 June 2003

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published in

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volume

197

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issue

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page(s)

1467-76

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cites work

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The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction

19 March 2017

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Molecular cloning of a cDNA encoding a human macrophage migration inhibitory factor

19 March 2017

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Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1

19 March 2017

1 reference

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MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia

19 March 2017

1 reference

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Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

19 March 2017

1 reference

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Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: regulatory role in the innate immune response

19 March 2017

1 reference

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Sustained mitogen-activated protein kinase (MAPK) and cytoplasmic phospholipase A2 activation by macrophage migration inhibitory factor (MIF). Regulatory role in cell proliferation and glucocorticoid action

19 March 2017

1 reference

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Mutation screening of the macrophage migration inhibitory factor gene: positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis

19 March 2017

1 reference

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Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Expression of the functional mature chloroplast triose phosphate translocator in yeast internal membranes and purification of the histidine-tagged protein by a single metal-affinity chromatography step

27 September 2017

1 reference

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Invariant chain induces B cell maturation by activating a TAF(II)105-NF-kappaB-dependent transcription program

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Migration-inhibitory factor gene-deficient mice are susceptible to cutaneous Leishmania major infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Attenuation of pulmonary neuroendocrine differentiation in mice lacking Clara cell secretory protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Macrophage migration inhibitory factor (MIF): its essential role in the immune system and cell growth

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Enzymatically inactive macrophage migration inhibitory factor inhibits monocyte chemotaxis and random migration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Macrophage migration inhibitory factor: cytokine, hormone, or enzyme?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

A role for the transmembrane domain in the trimerization of the MHC class II-associated invariant chain.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Alexa dyes, a series of new fluorescent dyes that yield exceptionally bright, photostable conjugates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

An essential role for macrophage migration inhibitory factor (MIF) in angiogenesis and the growth of a murine lymphoma.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Antisense macrophage migration inhibitory factor (MIF) prevents anti-IgM mediated growth arrest and apoptosis of a murine B cell line by regulating cell cycle progression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Targeted disruption of migration inhibitory factor gene reveals its critical role in sepsis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Specific reduction of insulin disulfides by macrophage migration inhibitory factor (MIF) with glutathione and dihydrolipoamide: potential role in cellular redox processes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

An essential regulatory role for macrophage migration inhibitory factor in T-cell activation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

An essential role for macrophage migration inhibitory factor in the tuberculin delayed-type hypersensitivity reaction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

CD44 and its interaction with extracellular matrix.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

The chondroitin sulfate form of invariant chain can enhance stimulation of T cell responses through interaction with CD44.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Assembly, transport, and function of MHC class II molecules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Characterization of a lymphocyte factor which alters macrophage functions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Expression cloning of the murine erythropoietin receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Surface expression of the invariant chain (CD74) is independent of concomitant expression of major histocompatibility complex class II antigens

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

MIF as a glucocorticoid-induced modulator of cytokine production

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Purification, bioactivity, and secondary structure analysis of mouse and human macrophage migration inhibitory factor (MIF).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Biosynthetic relationships of the chondroitin sulfate proteoglycan with Ia and invariant chain glycoproteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Macrophage migration inhibitory factor: a regulator of glucocorticoid activity with a critical role in inflammatory disease.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Recombinant IL-6 activates p42 and p44 mitogen-activated protein kinases in the IL-6 responsive B cell line, AF-10.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Transport properties of free and MHC class II-associated oligomers containing different isoforms of human invariant chain

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Two forms of the Ia antigen-associated invariant chain result from alternative initiations at two in-phase AUGs

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Human major histocompatibility complex class II invariant chain is expressed on the cell surface.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Control of fibroblast-like synoviocyte proliferation by macrophage migration inhibitory factor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Regulation of synoviocyte phospholipase A2 and cyclooxygenase 2 by macrophage migration inhibitory factor

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Quantitative analyses of binding affinity and specificity for glycolipid receptors by surface plasmon resonance.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Structure of a trimeric domain of the MHC class II-associated chaperonin and targeting protein Ii.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Requirement for invariant chain in B cell maturation and function.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193907

Protection from septic shock by neutralization of macrophage migration inhibitory factor

29 November 2018

1 reference

12 December 2020

Macrophage migration inhibitory factor antagonizes hydrocortisone-induced increases in cytosolic IkappaBalpha

1 reference

12 December 2020

Potent effects of low levels of MHC class II-associated invariant chain on CD4+ T cell development

1 reference

12 December 2020

Development of chronic colitis is dependent on the cytokine MIF

1 reference

12 December 2020

Regulation of macrophage migration inhibitory factor by endogenous glucocorticoids in rat adjuvant-induced arthritis

1 reference

12 December 2020

Characterization of catalytic centre mutants of macrophage migration inhibitory factor (MIF) and comparison to Cys81Ser MIF

1 reference

12 December 2020

Mechanism of a Reaction in Vitro Associated with Delayed-Type Hypersensitivity

1 reference

12 December 2020

Biochemical and Mutational Investigations of the Enzymatic Activity of Macrophage Migration Inhibitory Factor†

1 reference

12 December 2020

Migration inhibitory factor induces killing of Leishmania major by macrophages: dependence on reactive nitrogen intermediates and endogenous TNF-alpha

1 reference

12 December 2020

Macrophage migration inhibitory factor in rheumatoid arthritis: evidence of proinflammatory function and regulation by glucocorticoids

1 reference

12 December 2020

Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome

1 reference

12 December 2020

Differential expression of the invariant chain in mouse tumor cells: relationship to B lymphoid development

1 reference

12 December 2020

MIF regulates innate immune responses through modulation of Toll-like receptor 4

1 reference

12 December 2020

In vitro cell migration as a model for delayed hypersensitivity

1 reference

12 December 2020

A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20030286

1 reference

release_4tdlouja4jc3nexpvr2nz6swzq

Fatcat ID

0 references

1 reference

1 reference

1 reference