KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals (Q28507994)

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scientific journal article

Language	Label	Description	Also known as
English	KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals	scientific journal article

Statements

scholarly article

1 reference

PubMed publication ID

24 January 2017

KSR2 is a calcineurin substrate that promotes ERK cascade activation in response to calcium signals (English)

1 reference

PubMed publication ID

24 January 2017

Protein phosphatase 3, catalytic subunit, alpha isoform

1 reference

GOA release 2020-03-11

Kinase suppressor of ras 2

1 reference

GOA release 2020-03-11

Kinase suppressor of ras 1

1 reference

GOA release 2020-03-11

author name string

Michele K. Dougherty

1

1 reference

PubMed publication ID

24 January 2017

Daniel A. Ritt

2

1 reference

PubMed publication ID

24 January 2017

Ming Zhou

3

1 reference

PubMed publication ID

24 January 2017

Suzanne I. Specht

4

1 reference

PubMed publication ID

24 January 2017

Daniel M. Monson

5

1 reference

PubMed publication ID

24 January 2017

Timothy D. Veenstra

6

1 reference

PubMed publication ID

24 January 2017

Deborah K. Morrison

7

1 reference

PubMed publication ID

24 January 2017

publication date

26 June 2009

1 reference

PubMed publication ID

24 January 2017

1 reference

PubMed publication ID

24 January 2017

34

1 reference

PubMed publication ID

24 January 2017

6

1 reference

PubMed publication ID

24 January 2017

652–662

1 reference

PubMed publication ID

24 January 2017

Regulation of cell signaling dynamics by the protein kinase-scaffold Ste5

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Ras regulates assembly of mitogenic signalling complexes through the effector protein IMP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Identification of a novel human kinase supporter of Ras (hKSR-2) that functions as a negative regulator of Cot (Tpl2) signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Protein phosphatase 2A positively regulates Ras signaling by dephosphorylating KSR1 and Raf-1 on critical 14-3-3 binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

A second calcineurin binding site on the NFAT regulatory domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Identification of constitutive and ras-inducible phosphorylation sites of KSR: implications for 14-3-3 binding, mitogen-activated protein kinase binding, and KSR overexpression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Two-site interaction of nuclear factor of activated T cells with activated calcineurin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Murine Ksr interacts with MEK and inhibits Ras-induced transformation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Activation of mitogen-activating protein kinase by glucose is not required for insulin secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

KSR modulates signal propagation within the MAPK cascade

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

KSR, a novel protein kinase required for RAS signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

19 March 2017

Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

7 April 2017

Coordinating ERK/MAPK signalling through scaffolds and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

7 April 2017

Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

7 April 2017

Transcriptional regulation by calcium, calcineurin, and NFAT

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

7 April 2017

Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

The MEK/ERK cascade: from signaling specificity to diverse functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Scaffold proteins in MAP kinase signaling: more than simple passive activating platforms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

hKSR-2 inhibits MEKK3-activated MAP kinase and NF-kappaB pathways in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Calcium activation of ERK mediated by calmodulin kinase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Calcineurin anchoring and cell signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Integration of calcium and Ras signalling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

KSR is a scaffold required for activation of the ERK/MAPK module

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

The Ste5p scaffold.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Signaling to the nucleus by an L-type calcium channel-calmodulin complex through the MAP kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Activity-dependent CREB phosphorylation: convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Calcium, calcineurin, and the control of transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

Scaffold proteins may biphasically affect the levels of mitogen-activated protein kinase signaling and reduce its threshold properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

29 September 2017

CK2 Is a component of the KSR1 scaffold complex that contributes to Raf kinase activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

2 June 2018

The protein kinase KSR interacts with 14-3-3 protein and Raf.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

2 June 2018

Identification of the major phosphorylation sites of the Raf-1 kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

2 June 2018

Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

2 June 2018

Kinase suppressor of Ras1 compartmentalizes hippocampal signal transduction and subserves synaptic plasticity and memory formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

27 November 2018

Regulation of ERK1 and ERK2 by glucose and peptide hormones in pancreatic beta cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

27 November 2018

RAS oncogenes: the first 30 years.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

27 November 2018

C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

27 November 2018

A Ras-mediated signal transduction pathway is involved in the control of sex myoblast migration in Caenorhabditis elegans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2737517

27 November 2018

MAP kinase pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/19560418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of NFAT activation by the second calcineurin binding site

1 reference

https://pubmed.ncbi.nlm.nih.gov/19560418

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.MOLCEL.2009.06.001

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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