It's all relative.

Travels With My Aunt by Graham Greene
Uncle Silas: A Tale of Bartram-Hough by J. Sheridan Le Fanu
The Granny by Brendan O'Carroll
Sons and Lovers by D. H. Lawrence
The Wednesday Sisters by Meg Waite Clayton

Cousin Phillis
Mon Oncle
Wives and Daughters
Kushiel's Scion
The Descendants

Sister Carrie by Theodore Dreiser
Brother Cadfael's Penance by Ellis Peters
Is your Mama a Llama? by Deborah Guarino
Daddy Long Legs by Jean Webster
The Magician's Nephew by CS Lewis

The Brothers Karamazov by Fyodor Dostoevsky
My Uncle Silas by H. E. Bates
Wyrd Sisters by Terry Pratchett
Faro's Daughter by Georgette Heyer
Shakespeare's Wife by Germaine Greer

Every Day Is Mother's Day, by Hilary Mantel
The Pogo Stepmother Goose, by Walt Kelly
Shakespeare's Sisters: Women Writers Bridge Five Centuries, by Gigi Bradford
Too Many Cousins, by Douglas G. Browne

and a three (or four?) -fer: I, Pierre Rivière, Having Slaughtered My Mother, My Sister, and My Brother ...: A Case of Parricide in the 19th Century, by Michel Foucault

The father hunt by Rex Stout
Cousine Bette by Honore de Balzac
The complete Uncle Abner by Melville Davisson Post
Mama's bank account by Katherine Forbes
Murder's little sister by Pamela Branch

Flags of Our Fathers by James Bradley
Grandmother and the Priests by Taylor Caldwell
Life With Father by Clarence Day
Around the World with Auntie Mame by Patrick Dennis
Sugar Daddy by Lisa Kleypas

Fathers and Sons by Ivan Turgenev
Dombey and Son by Charles Dickens
The Rice Mother by Rani Manicka
Brother Sun, Sister Moon by Katherine Patterson
Uncle Vanya by Anton Chekhov

Hitler's Niece by Ron Hansen
Stepfather's Slaves by Jack Warren
The Sibling Bond by Stephen P Bank
Once Removed by Mako Yoshikawa
Auntie Yang's Great Soybean Picnic by Ginnie Lo

Four Sisters of Hofei: A History by Ann-Ping Chin
Eight Cousins; Or, the Aunt-Hill by Louisa May Alcott
The Soul Brothers and Sister Lou by Kristin Hunter
Mama Day by Gloria Naylor
Native Son by Richard Wright

The Sisters Brothers by Patrick deWitt
Little Brother by Cory Doctorow
Brother Nature by Robert Llewellyn
The King of Elfland's Daughter by Lord Dunsany
First Family by Patrick Tilley

Wizard's Daughter by Catherine Coulter
Daddy Long Legs by Jean Webster
Motherless Brooklyn by Jonathan Lethem
Father and Son by Peter Maas
Her Mother's Keeper by Nora Roberts

Mother of Pearl by Melinda Haynes
The Hummingbird's Daughter by Luis Alberto Urrea
Founding Mothers: The Women Who Raised Our Nation by Cokie Roberts
Band of Brothers by Stephen E. Ambrose
Five Families: Mexican Case Studies in the Culture of Poverty byn Oscar Lewis

The Spice Merchant's Daughter by Christina Arokiasamy
The Doctor's Wife by Mary Elizabeth Braddon
The Weird Sisters by Eleanor Brown
The Adventures of Grandfather Frog by Thornton W. Burgess
Ramona and Her Father by Beverly Cleary

Elizabeth and Mary: Cousins, Rivals, Queens by Jane Dunn
The Three Incestuous Sisters by Audrey Niffenegger
My Sister's Keeper by Jodi Picoult
Not Becoming My Mother: and Other Things She Taught Me Along the Way by Ruth Reichl
The Time Traveler's Wife by Audrey Niffenegger

The Penderwicks : a summer tale of four sisters, two rabbits, and a very interesting boy by Jeanne Birdsall
Wyrd Sisters by Terry Pratchett
The summer of the great-grandmother by Madeleine L'Engle
Murphy must have been a mother! : (and other laws I live by) by Teresa Bloomingdale
Patches of Godlight: Father Tim's Favorite Quotes (Mitford Years) by Jan Karon

Uncle Tomʻs Cabin
by Harriet Beecher Stowe

Travels with my Aunt
by Graham Greene

Manʻs Poor Relations
by Ernest Hooton

The Brothers Ashkenazi
by Israel Joshua Singer

La Cousine Bette / Cousin Bette by Honore de Balzac

Take two for me:

Dearest Cousin Jane by Jill Pitkeathley
My granny went to market : a round-the-world counting rhyme by Stella Blackstone
Letters to my daughters by Mary Matalin
Dreams from my father by Barack Obama
The Care Bear Cousins' Mystery Adventure by Sonia Black

Strangers and Brothers by C.P. Snow
Buying a Fishing Rod for my Grandfather by Gao Xingjian
Not without my Daughter by Betty Mahmoody
The Son by Jo Nesbo
The Good Husband of Zebra Drive by Alexander McCall-Smith

Uncle Vanya
by Anton Chekhov

"Daddy" Grace
by Marie Dallam

Men and Brethren
by James Gould Cozzens

The Brothers Ashkenazi
by I. J. Singer

Sister Carrie
by Theodore Dreiser

Galileo's Daughter by Dava Sobel
Native Son by Richard Wright
The Confession of Brother Haluin by Ellis Peters
The Godfather by Mario Puzo
Daughter of Fortune by Isabel Allende

Shadows of Forgotten Ancestors by Carl Sagan
The Mother Tongue: English and How It Got That Way by Bill Bryson
The Peabody Sisters by Megan Marshall
The Annotated Brothers Grimm by Jacob Grimm
Founding Brothers: The Revolutionary Generation by Joseph J Ellis

The orphan master's son by Adam Johnson
Wild swans : three daughters of China by Jung Chang
The pregnant widow by Martin Amis
In praise of the stepmother by Mario Vargas Llosa
The scandal of Father Brown by G. K. Chesterton

Fathers and Sons
by Ivan Turgenev

Mother Night by Kurt Vonnegut

The Father (drama) by August Strindberg

The Case of the Sleepwalkers Niece
by Erle Stanley Gardner

The Father; (poetry) by Sharon Olds

Tales from Uncle Remus
by Joel Chandler Harris

Becoming Sister Wives: The Story of an Unconventional Marriage by Kody Brown
For My Brother Jesus by Irving Layton
Madame Bovary by Gustave Flaubert
Daughter of Time by Josephine Tey
An Ideal Husband by Oscar Wilde

Mijn Tante Coleta /
My Aunt Coleta
by* Geert Van Oorschot

Rennys Daughter
by Mazo de la Roche

Tante Lucietta / Aunt Lucietta by*

Father of the Bride
by Edward Streeter

A Son of the Middle Border
by Hamlin Garland

*Not guaranteeing that there is any English ed.

Too Many Mothers: A Memoir of an East End Childhood by Roberta Taylor
Sons of Fortune by Jeffrey Archer
The General's Daughter by Nelson DeMille
The Alphabet Sisters by Monica McInerney
Wolf's Brother by Megan Lindholm

De Tweeling = the Twin by Tessa de Loo
The Twin by Gerbrand Bakker
Brieven aan mijn kleinzoon by Abel J. Herzberg
De zoon uit Spanje by Tessa de Loo
Sirkusdirektørens datter = The Ringmasters Daughter by Jostein Gaarder

My Animals and Other Family by Clare Balding
The Rector's Wife by Joanna Trollope
A Clergyman's Daughter by George Orwell
Wedlock: how georgian Britain's worst husband met his match by Wendy Moore
The Complete Book of Aunts by Rupert Chritianson

By My Brother's Side by Tiki Barber
Auntie Mame by Jerome Lawrence
Grandfather's Journey by Allen Say
My Sister Eileen by Ruth McKenney
How My Parents Learned to Eat by Ina R. Friedman

Daddy-Long-Legs
Summer of the Great-Grandmother
Sister Carrie
Mama's Going to buy You a Mockingbird
Sons from Afar

The Great-grandmother by Nancy-Hale

Papa Small by Lois Lenski

Grandad, itʻs Morning by Bil Keane

An Auntʻs Story by Patrick White

Letters Written to his Brother Harold
by S. D. Rogers